(Q36607286)

15 August 2017

1 reference

title

Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics (English)

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15 August 2017

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1 reference

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Natalie J Serkova

1

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PubMed ID

17009906

15 August 2017

Claus U Niemann

series ordinal

2

1 reference

15 August 2017

1 September 2006

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

15 August 2017

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15 August 2017

6

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15 August 2017

717-731

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15 August 2017

5

1 reference

Metabolic profiles to define the genome: can we hear the phenotypes?

15 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolic profiles of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolomics: the principles and potential applications to transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomic modeling of drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomics in toxicology: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolomics reviewed: a new "omics" platform technology for systems biology and implications for natural products research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

High-resolution serum proteomic features for ovarian cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Cancer diagnosis using proteomic patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Use of proteomic patterns in serum to identify ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Differential exoprotease activities confer tumor-specific serum peptidome patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolomics takes its place as latest up-and-coming "omic" science.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

1H NMR analysis for metabolites in serum and urine from rats administrated chronically with La(NO3)3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

NMR spectroscopic studies on the late onset form of 3-methylglutaconic aciduria type I and other defects in leucine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

beta-Ureidopropionase deficiency: a novel inborn error of metabolism discovered using NMR spectroscopy on urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolomics: an emerging post-genomic tool for nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolic profiling of livers and blood from obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

A biochemical prognostic model of outcome in paracetamol-induced acute liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

A decrease in 1H nuclear magnetic resonance spectroscopically determined citrate in human seminal fluid accompanies the development of prostate adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

High-resolution 1H nuclear magnetic resonance spectroscopy analysis of bile samples obtained from a patient after orthotopic liver transplantation: new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Potential biological markers for cerebrovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

High-resolution (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Non-destructive quantitation of spermine in human prostate tissue samples using HRMAS 1H NMR spectroscopy at 9.4 T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

A comparison of cell and tissue extraction techniques using high-resolution 1H-NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolite concentrations in human term placentae and their changes due to delayed collection after delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Quantification of phosphocholine and glycerophosphocholine with 31P edited 1H NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Improved signal to noise in high-resolution magic angle spinning total correlation spectroscopy studies of prostate tissues using rotor-synchronized adiabatic pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Chemometric contributions to the evolution of metabonomics: mathematical solutions to characterising and interpreting complex biological NMR spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomic investigations into hydrazine toxicity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Intracellular transport mechanisms: a critique of diffusion theory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabonomics: a platform for studying drug toxicity and gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Drug-related hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

31P MRS of heart grafts provides metabolic markers of early dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolic differences between primary and recurrent human brain tumors: a 1H NMR spectroscopic investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Pattern recognition analysis of 1H NMR spectra from perchloric acid extracts of human brain tumor biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Analysis of volume MRI and MR spectroscopic imaging data for the evaluation of patients with brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Magnetic resonance imaging and spectroscopic imaging: Improved patient selection and potential for metabolic intermediate endpoints in prostate cancer chemoprevention trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Single-voxel oversampled J-resolved spectroscopy of in vivo human prostate tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Real-time changes in 1H and 31P NMR spectra of malignant human mammary epithelial cells during treatment with the anti-inflammatory agent indomethacin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

In vivo quantification of choline compounds in the breast with 1H MR spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Specificity of choline metabolites for in vivo diagnosis of breast cancer using 1H MRS at 1.5 T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Detection of resistance to imatinib by metabolic profiling: clinical and drug development implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

1H-NMR and 13C-NMR lipid profiles of human renal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

High-resolution proton nuclear magnetic resonance spectroscopy of ovarian cyst fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolomic identification of novel biomarkers of myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

An NMR metabolomic investigation of early metabolic disturbances following traumatic brain injury in a mammalian model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Novel Risk Markers and Clinical Practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Frontiers in nutrigenomics, proteomics, metabolomics and cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Noninvasive monitoring of citrate, acetate, lactate, and renal medullary osmolyte excretion in urine as biomarkers of exposure to ischemic reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Metabolite identification in human liver needle biopsies by high-resolution magic angle spinning 1H NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.5.717

21 January 2018

Identifiers

DOI

10.1586/14737159.6.5.717

1 reference

15 August 2017

1 reference

PubMed ID

17009906