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Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo.
scientific article published on 8 May 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
title
Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
main subject
neuroblastoma
1 reference
based on heuristic
inferred from title
tretinoin
1 reference
based on heuristic
inferred from title
author
Jane L Armstrong
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
Alan V. Boddy
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
Christopher Redfern
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
Gareth J Veal
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
author name string
G A Taylor
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
H D Thomas
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
language of work or name
English
0 references
publication date
8 May 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
published in
British Journal of Cancer
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
volume
96
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
page(s)
1675-1683
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
cites work
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - a study of the United Kingdom Children's Cancer Study Group.
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PubMed Central
reference URL
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Skin retinoid concentrations are modulated by CYP26AI expression restricted to basal keratinocytes in normal human skin and differentiated 3D skin models
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30 September 2017
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30 September 2017
Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells
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13-cis retinoic acid and isomerisation in paediatric oncology--is changing shape the key to success?
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Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells
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Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.
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A Novel Human Cytochrome P450, CYP26C1, Involved in Metabolism of 9-cis and All-trans Isomers of Retinoic Acid
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Retinoid therapy of high-risk neuroblastoma.
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30 September 2017
Cytochrome p450 retinoic acid 4-hydroxylase inhibitors: potential agents for cancer therapy
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PubMed Central
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30 September 2017
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
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PubMed Central
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30 September 2017
Influence of isomerisation on the growth inhibitory effects and cellular activity of 13-cis and all-trans retinoic acid in neuroblastoma cells
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PubMed Central
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30 September 2017
Cellular metabolism and actions of 13-cis-retinoic acid
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30 September 2017
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites
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30 September 2017
13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors
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30 September 2017
Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism
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30 September 2017
Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group
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30 September 2017
cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
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30 September 2017
Phase I trial of 13-cis-retinoic acid in children with neuroblastoma following bone marrow transplantation
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30 September 2017
A human retinoic acid receptor which belongs to the family of nuclear receptors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359919
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30 September 2017
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid
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30 September 2017
Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia
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Regulation of cutaneous drug-metabolizing enzymes and cytoprotective gene expression by topical drugs in human skin in vivo.
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20 September 2018
Activation of retinoic acid receptor-dependent transcription by all-trans-retinoic acid metabolites and isomers
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20 September 2018
Human cytochrome P450s involved in the metabolism of 9-cis- and 13-cis-retinoic acids
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20 September 2018
The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo
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stated in
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20 September 2018
Antitumor activity, distribution, and metabolism of 13-cis-retinoic acid as a single agent or in combination with tamoxifen in established human MCF-7 xenografts in mice.
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20 September 2018
Identifiers
DOI
10.1038/SJ.BJC.6603779
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
PMC publication ID
2359919
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
PubMed publication ID
17486130
1 reference
stated in
Europe PubMed Central
PMC publication ID
2359919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486130%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
ResearchGate publication ID
6345533
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