(Q36610161)

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Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes

scientific article published on 6 March 2007

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Europe PubMed Central

PMC publication ID

15 August 2017

Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes (English)

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Europe PubMed Central

PMC publication ID

15 August 2017

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C Feder-Mengus

1

1 reference

Europe PubMed Central

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15 August 2017

S Ghosh

2

1 reference

Europe PubMed Central

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15 August 2017

W P Weber

3

1 reference

Europe PubMed Central

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15 August 2017

S Wyler

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

P Zajac

5

1 reference

Europe PubMed Central

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15 August 2017

L Terracciano

6

1 reference

Europe PubMed Central

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15 August 2017

D Oertli

7

1 reference

Europe PubMed Central

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15 August 2017

M Heberer

8

1 reference

Europe PubMed Central

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15 August 2017

I Martin

9

1 reference

Europe PubMed Central

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15 August 2017

G C Spagnoli

10

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Europe PubMed Central

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15 August 2017

A Reschner

11

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Europe PubMed Central

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15 August 2017

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publication date

6 March 2007

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Europe PubMed Central

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15 August 2017

British Journal of Cancer

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Europe PubMed Central

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15 August 2017

96

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Europe PubMed Central

PMC publication ID

15 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1072-1082

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Cancer's molecular sweet tooth and the Warburg effect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Tumor hypoxia and cancer progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Comparison of alamar blue and MTT assays for high through-put screening

1 reference

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30 September 2017

Quiescent phenotype of tumor-specific CD8+ T cells following immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Active-specific immunization against melanoma: is the problem at the receiving end?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Intranodal Administration of Peptide-Pulsed Mature Dendritic Cell Vaccines Results in Superior CD8+T-Cell Function in Melanoma Patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

On the Origin of Cancer Cells

1 reference

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30 September 2017

Increased TIA-1 gene expression in the tumor microenvironment after locoregional administration of tumor necrosis factor-alpha to patients with soft tissue limb sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Tumors as elusive targets of T-cell-based active immunotherapy

1 reference

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30 September 2017

Induction of "antigen silencing" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Genetic models in applied physiology: invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

High density oligonucleotide array analysis of interferon- alpha2a sensitivity and transcriptional response in melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

A listing of human tumor antigens recognized by T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Forecasting the growth of multicell tumour spheroids: implications for the dynamic growth of solid tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Multicellular resistance: a paradigm for clinical resistance?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Generation of human T-cell responses to an HLA-A2.1-restricted peptide epitope derived from alpha-fetoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Three-dimensional spheroid model in tumor biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Nuclear targeting of the serine protease granzyme A (fragmentin-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Suboptimal activation of melanoma infiltrating lymphocytes (TIL) due to low avidity of TCR/MHC-tumor peptide interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Transcriptional regulation of HLA-A and -B: differential binding of members of the Rel and IRF families of transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

c-myc down-regulates class I HLA expression in human melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Cell and environment interactions in tumor microregions: the multicell spheroid model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

30 September 2017

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

1 reference

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28 June 2018

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

28 June 2018

Role of cell shape in growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

28 June 2018

Culture of melanoma cells in 3-dimensional architectures results in impaired immunorecognition by cytotoxic T lymphocytes specific for Melan-A/MART-1 tumor-associated antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Real-time polymerase chain reaction determination of cytokine mRNA expression profiles in Hodgkin's lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Rapid induction of specific cytotoxic T lymphocytes against melanoma-associated antigens by a recombinant vaccinia virus vector expressing multiple immunodominant epitopes and costimulatory molecules in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360115

20 September 2018

Size-dependent oxygenation and energy status in multicellular tumor spheroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanoma antigen recognition by tumour-infiltrating T lymphocytes (TIL): effect of differential expression of melan-A/MART-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of self-recognition in multiple sclerosis by single-cell analysis of cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of human bladder cancer cell architecture on autologous T-lymphocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship of natural killer cell counts, perforin mRNA and CD2 expression to post-exercise natural killer cell activity in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of interferon-alpha on gene expression of chemokines and members of the tumour necrosis factor superfamily in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peritoneal exudate lymphocyte and mixed lymphocyte culture hybridomas are cytolytic in the absence of cytotoxic cell proteinases and perforin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nIFN beta and rIFN gamma on growth and morphology of two human melanoma cell lines: comparison between two- and three-dimensional culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17342088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

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7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.BJC.6603664

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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