(Q36615006)

15 August 2017

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title

CFTR (ABCC7) is a hydrolyzable-ligand-gated channel (English)

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15 August 2017

Andrei A Aleksandrov

1

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PubMed ID

17021796

15 August 2017

Luba A Aleksandrov

series ordinal

2

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PubMed ID

17021796

15 August 2017

John R Riordan

series ordinal

3

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15 August 2017

26 September 2006

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15 August 2017

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15 August 2017

453

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15 August 2017

5

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15 August 2017

693-702

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https://scigraph.springernature.com/pub.10.1007/s00424-006-0140-z

15 August 2017

0 references

cites work

Cyclic nucleotide-gated ion channels

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00424-006-0140-Z

Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme

21 January 2018

1 reference

12 December 2020

Identification of the cystic fibrosis gene: chromosome walking and jumping

1 reference

12 December 2020

The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover

1 reference

12 December 2020

A recombinant polypeptide model of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator functions as an active ATPase, GTPase and adenylate kinase.

1 reference

12 December 2020

The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

1 reference

12 December 2020

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain

1 reference

12 December 2020

Chloride impermeability in cystic fibrosis

1 reference

12 December 2020

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

1 reference

12 December 2020

Expression and functional properties of the second predicted nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator fused to glutathione-S-transferase.

1 reference

12 December 2020

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

12 December 2020

Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis

1 reference

12 December 2020

Purification and crystallization of the cystic fibrosis transmembrane conductance regulator (CFTR).

1 reference

12 December 2020

Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.

1 reference

12 December 2020

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1 reference

12 December 2020

Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis

1 reference

12 December 2020

Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.

1 reference

12 December 2020

Nucleotide Dependent Monomer/Dimer Equilibrium of OpuAA, the Nucleotide-binding Protein of the Osmotically Regulated ABC Transporter OpuA from Bacillus subtilis

1 reference

12 December 2020

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells

1 reference

12 December 2020

Nucleotide-binding domain 1 of cystic fibrosis transmembrane conductance regulator production of a suitable protein for structural studies

1 reference

12 December 2020

ATP alters current fluctuations of cystic fibrosis transmembrane conductance regulator: evidence for a three-state activation mechanism

1 reference

12 December 2020

PKC-mediated stimulation of amphibian CFTR depends on a single phosphorylation consensus site. insertion of this site confers PKC sensitivity to human CFTR.

1 reference

12 December 2020

Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis.

1 reference

12 December 2020

Dibasic phosphorylation sites in the R domain of CFTR have stimulatory and inhibitory effects on channel activation

1 reference

12 December 2020

Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle

1 reference

12 December 2020

Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)

1 reference

12 December 2020

Regulation of CFTR Cl- channel gating by ADP and ATP analogues

1 reference

12 December 2020

Protein kinase-independent activation of CFTR by phosphatidylinositol phosphates

1 reference

12 December 2020

ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR.

1 reference

12 December 2020

Regulation of CFTR ion channel gating by MgATP.

1 reference

12 December 2020

Regulation of CFTR channel gating

1 reference

12 December 2020

Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia

1 reference

12 December 2020

Nucleoside triphosphates are required to open the CFTR chloride channel.

1 reference

12 December 2020

cAMP-independent phosphorylation activation of CFTR by G proteins in native human sweat duct

1 reference

12 December 2020

Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating

1 reference

12 December 2020

Phosphorylation fails to activate chloride channels from cystic fibrosis airway cells

1 reference

12 December 2020

ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity.

1 reference

12 December 2020

A Maxwell's Demon type of membrane transport: possibility for active transport by ABC-type transporters?

1 reference

12 December 2020

On the mechanism of MgATP-dependent gating of CFTR Cl- channels

1 reference

12 December 2020

Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding

1 reference

12 December 2020

A conditional probability analysis of cystic fibrosis transmembrane conductance regulator gating indicates that ATP has multiple effects during the gating cycle

1 reference

12 December 2020

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

1 reference

12 December 2020

A recombinant polypeptide model of the second predicted nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator is a GTP-binding protein

1 reference

12 December 2020

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains

1 reference

12 December 2020

Cl- channels in CF: lack of activation by protein kinase C and cAMP-dependent protein kinase

1 reference

12 December 2020

Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis.

1 reference

12 December 2020

Apical heterotrimeric g-proteins activate CFTR in the native sweat duct

1 reference

12 December 2020

The CFTR chloride channel: nucleotide interactions and temperature-dependent gating

1 reference

12 December 2020

Biosynthesis and degradation of CFTR.

1 reference

12 December 2020

Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

1 reference

12 December 2020

The ABC protein turned chloride channel whose failure causes cystic fibrosis

1 reference

12 December 2020

Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains

1 reference

12 December 2020

Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure

1 reference

12 December 2020

Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Lack of conventional ATPase properties in CFTR chloride channel gating

1 reference

12 December 2020

Nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator, an ABC transporter, catalyze adenylate kinase activity but not ATP hydrolysis.

1 reference

12 December 2020

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.

1 reference

12 December 2020

Differential interactions of nucleotides at the two nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

12 December 2020

Nucleoside triphosphate pentose ring impact on CFTR gating and hydrolysis

1 reference

12 December 2020

Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum

1 reference

12 December 2020

Structure and function of the CFTR chloride channel

1 reference

12 December 2020

ATPase activity of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia

1 reference

12 December 2020

The first nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator can function as an active ATPase

1 reference

12 December 2020

Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Degradation of CFTR by the ubiquitin-proteasome pathway

1 reference

12 December 2020

Abnormal Ion Permeation Through Cystic Fibrosis Respiratory Epithelium

1 reference

12 December 2020

Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters

1 reference

12 December 2020

ATP hydrolysis by a CFTR domain: pharmacology and effects of G551D mutation

1 reference

12 December 2020

The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating

1 reference

12 December 2020

Assembly of functional CFTR chloride channels

1 reference

12 December 2020

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1 reference

12 December 2020

Mutation of R555 in CFTR-delta F508 enhances function and partially corrects defective processing.

1 reference

12 December 2020

Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells

1 reference

12 December 2020

CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.

1 reference

12 December 2020

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1 reference

12 December 2020

10.1007/S00424-006-0140-Z

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17021796