(Q36617473)

15 August 2017

Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53 (English)

1 reference

15 August 2017

1 reference

F S Wyllie

1

1 reference

15 August 2017

M F Haughton

series ordinal

2

1 reference

15 August 2017

J M Rowson

series ordinal

3

1 reference

15 August 2017

D Wynford-Thomas

series ordinal

4

1 reference

15 August 2017

language of work or name

English

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publication date

1 March 1999

1 reference

British Journal of Cancer

15 August 2017

1 reference

15 August 2017

79

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15 August 2017

7-8

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15 August 2017

1111-1120

1 reference

Molecular genetics of thyroid cancer

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

An information-intensive approach to the molecular pharmacology of cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

The tumour suppressor gene p53 as a regulator of proliferative life-span and tumour progression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Spontaneous de-differentiation correlates with extended lifespan in transformed thyroid epithelial cells: an epigenetic mechanism of tumour progression?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Interference with p53 protein inhibits hematopoietic and muscle differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Effects of p53 mutants on wild-type p53-mediated transactivation are cell type dependent.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Monoclonal antibodies specific for simian virus 40 tumor antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Strontium phosphate transfection of human cells in primary culture: stable expression of the simian virus 40 large-T-antigen gene in primary human bronchial epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

A genetic model for colorectal tumorigenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Suppression of human colorectal carcinoma cell growth by wild-type p53

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Participation of p53 protein in the cellular response to DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Involvement of wild-type p53 in pre-B-cell differentiation in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Mutation of the p53 gene in a differentiated human thyroid carcinoma cell line, but not in primary thyroid tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Conditional immortalization of human thyroid epithelial cells: a tool for analysis of oncogene action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Mutant p53 is not fully dominant over endogenous wild type p53 in a colorectal adenoma cell line as demonstrated by induction of MDM2 protein and retention of a p53 dependent G1 arrest after gamma irradiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

A mutated p53 gene alters thyroid cell differentiation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Sensitivity to genotoxic effects of bleomycin in humans: possible relationship to environmental carcinogenesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Frequent association of p53 gene mutation in invasive bladder cancer

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Expression of the normal p53 gene induces differentiation of K562 cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Interaction between p53 and TGF beta 1 in control of epithelial cell proliferation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Structure and expression of nuclear oncogenes in multi-stage thyroid tumorigenesis

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Thyroid epithelial cell transformation by a retroviral vector expressing SV40 large T.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362227

Cloning of human thyroglobulin complementary DNA

20 September 2018

1 reference

12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

12 December 2020

Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SDI1/WAF1

1 reference

12 December 2020

Immunohistochemical detection of p53 protein in mammary carcinoma: an important new independent indicator of prognosis?

1 reference

12 December 2020

Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland

1 reference

12 December 2020

Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms

1 reference

12 December 2020

Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells

1 reference

12 December 2020

Sunburn and p53 in the onset of skin cancer

1 reference

12 December 2020

Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

Anaplastic thyroid carcinoma. A study of 70 cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

Characterization and radiosensitivity at high or low dose rate of four cell lines derived from human thyroid tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 gene is up-regulated during skeletal muscle cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 mutations: gains or losses?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53 protein accumulation and gene mutation in the progression of human prostate carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

Direct growth stimulation of normal human epithelial cells by mutant p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

p53: guardian of cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690177

7 January 2021

Identifiers

DOI

10.1038/SJ.BJC.6690177

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

10098744

1 reference