(Q36618916)

15 August 2017

SecYEG activates GTPases to drive the completion of cotranslational protein targeting (English)

1 reference

15 August 2017

David Akopian

1

1 reference

15 August 2017

Kush Dalal

2

1 reference

15 August 2017

Kuang Shen

3

1 reference

15 August 2017

Franck Duong

4

1 reference

15 August 2017

Shu-ou Shan

5

1 reference

15 August 2017

language of work or name

English

0 references

publication date

11 February 2013

1 reference

15 August 2017

9

1 reference

inferred from page(s)

published in

Journal of Cell Biology

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15 August 2017

200

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15 August 2017

4

1 reference

15 August 2017

397-405

1 reference

Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

A single copy of SecYEG is sufficient for preprotein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Site-specific fluorescent labeling of nascent proteins on the translating ribosome.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The oligomeric state and arrangement of the active bacterial translocon

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Genetic evidence for functional interaction of the Escherichia coli signal recognition particle receptor with acidic lipids in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The action of cardiolipin on the bacterial translocon.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Signal recognition particle (SRP) and SRP receptor: a new paradigm for multistate regulatory GTPases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The lateral gate of SecYEG opens during protein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Delivering proteins for export from the cytosol

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Multiple conformational switches in a GTPase complex control co-translational protein targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Ribosome binding of a single copy of the SecY complex: implications for protein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Protein translocation across the bacterial cytoplasmic membrane.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Preprotein-controlled catalysis in the helicase motor of SecA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Membrane binding of the bacterial signal recognition particle receptor involves two distinct binding sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Signal recognition particle receptor exposes the ribosomal translocon binding site.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Mechanism of association and reciprocal activation of two GTPases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The core Escherichia coli signal recognition particle receptor contains only the N and G domains of FtsY

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Substrate twinning activates the signal recognition particle and its receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

X-ray structure of a protein-conducting channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Structural determinants of SecB recognition by SecA in bacterial protein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

SRbeta coordinates signal sequence release from SRP with ribosome binding to the translocon

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Anionic phospholipids are involved in membrane association of FtsY and stimulate its GTPase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Signal sequence recognition in cotranslational translocation by protein components of the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Crystal structure of the NG domain from the signal-recognition particle receptor FtsY

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Preserving the membrane barrier for small molecules during bacterial protein translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Demonstration of a multistep mechanism for assembly of the SRP x SRP receptor complex: implications for the catalytic role of SRP RNA.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Generation of ribosome nascent chain complexes for structural and functional studies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Helical distribution of the bacterial chemoreceptor via colocalization with the Sec protein translocation machinery

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Subcellular sites for bacterial protein export

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

An E. coli Ribonucleoprotein Containing 4.5 S RNA Resembles Mammalian Signal Recognition Particle

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575545

Reconstitution of the SecY translocon in nanodiscs.

28 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Colorimetric Method for Determination of Sugars and Related Substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Expression, crystallization and preliminary X-ray diffraction study of FtsY, the docking protein of the signal recognition particle of E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Role of SRP RNA in the GTPase cycles of Ffh and FtsY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Phosphatidylethanolamine and phosphatidylglycerol are segregated into different domains in bacterial membrane. A study with pyrene-labelled phospholipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Reconstitution of Purified Bacterial Preprotein Translocase in Liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

The Bacterial SRP Receptor, SecA and the Ribosome Use Overlapping Binding Sites on the SecY Translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201208045

Visualization of membrane domains in Escherichia coli

21 January 2018

1 reference

12 December 2020

Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel

1 reference

12 December 2020

A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane

1 reference

12 December 2020

Interaction between SecA and SecYEG in Micellar Solution and Formation of the Membrane-Inserted State†

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.201208045

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23401005

1 reference