(Q36618965)

English

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

scientific article published on February 1999

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG). (English)

1 reference

Europe PubMed Central

15 August 2017

author name string

Kuin A

1

1 reference

Europe PubMed Central

15 August 2017

Aalders M

2

1 reference

Europe PubMed Central

15 August 2017

Lamfers M

3

1 reference

Europe PubMed Central

15 August 2017

van Zuidam DJ

4

1 reference

Europe PubMed Central

15 August 2017

Essers M

5

1 reference

Europe PubMed Central

15 August 2017

Beijnen JH

6

1 reference

Europe PubMed Central

15 August 2017

Smets LA

7

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

1 February 1999

1 reference

Europe PubMed Central

15 August 2017

British Journal of Cancer

1 reference

Europe PubMed Central

15 August 2017

79

1 reference

Europe PubMed Central

15 August 2017

793-801

1 reference

Europe PubMed Central

15 August 2017

5-6

1 reference

Europe PubMed Central

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690127

0 references

Molecular targeting of mitomycin C chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

pH in human tumour xenografts: effect of intravenous administration of glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

Melphalan tissue concentrations in patients treated with regional isolated perfusion for melanoma of the lower limb

1 reference

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30 September 2017

In vivo metabolic effects of hyperglycemia in murine radiation-induced fibrosarcoma: a 31P NMR investigation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

The relevance of tumour pH to the treatment of malignant disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1 reference

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In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

Thermosensitization by increasing intracellular acidity with amiloride and its analogs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

30 September 2017

Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Tumor-selective modification of cellular microenvironment in vivo: effect of glucose infusion on the pH in normal and malignant rat tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

A new mouse tumor model system (RIF-1) for comparison of end-point studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Extracellular pH, transmembrane distribution and cytotoxicity of chlorambucil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Influence of microenvironmental pH on adriamycin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Modulation of murine radiation-induced fibrosarcoma-1 tumor metabolism and blood flow in situ via glucose and mannitol administration monitored by 31P and 2H nuclear magnetic resonance spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362690

28 June 2018

Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of intratumoral pH by the mitochondrial inhibitor m-iodobenzylguanidine and moderate hyperglycemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of chlorambucil cytotoxicity by combination with flavone acetic acid in a murine tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of tumour intracellular pH and enhancement of melphalan cytotoxicity by the ionophore Nigericin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EO9 phase II study in advanced breast, gastric, pancreatic and colorectal carcinoma by the EORTC Early Clinical Studies Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical characterization and comparative cellular effects of meta-iodobenzyl guanidine and benzyl guanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal toxicity of the neuron-blocking and mitochondriotropic agent m-iodobenzylguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphofructokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta-difluorochlorambucil (CB 7103) in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of compounds that interfere with the regulation of intracellular pH: a potential new class of anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proton-mediated liberation of aldophosphamide from a nontoxic prodrug: a strategy for tumor-selective activation of cytocidal drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial respiration and stimulated glycolysis by m-iodobenzylguanidine (MIBG)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hypoxia and low pH on the cytotoxicity of chlorambucil

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of DNA-adduct formation and cytotoxicity of platinum-containing drugs by low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of human tumor pH by elevation of blood glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/10070871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6690127

1 reference

Europe PubMed Central

15 August 2017

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0 references

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

ResearchGate publication ID

0 references

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