(Q36621987)

15 August 2017

2 references

22 October 2022

The coronavirus replicase: insights into a sophisticated enzyme machinery (English)

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15 August 2017

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John Ziebuhr

1

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15 August 2017

language of work or name

English

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publication date

1 January 2006

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Advances in Experimental Medicine and Biology

15 August 2017

published in

2 references

15 August 2017

22 October 2022

581

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15 August 2017

page(s)

3-11

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Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer

15 August 2017

cites work

1 reference

12 December 2020

Virus-encoded proteinases and proteolytic processing in the Nidovirales.

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12 December 2020

The nucleoprotein is required for efficient coronavirus genome replication.

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12 December 2020

The nsp9 replicase protein of SARS-coronavirus, structure and functional insights

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12 December 2020

Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease.

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12 December 2020

Design of wide-spectrum inhibitors targeting coronavirus main proteases

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12 December 2020

Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily

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12 December 2020

An efficient ribosomal frame-shifting signal in the polymerase-encoding region of the coronavirus IBV.

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12 December 2020

Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations

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12 December 2020

Major genetic marker of nidoviruses encodes a replicative endoribonuclease

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12 December 2020

Coronavirus mRNA synthesis involves fusion of non-contiguous sequences

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12 December 2020

Conservation of substrate specificities among coronavirus main proteases

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12 December 2020

Characterization of the expression, intracellular localization, and replication complex association of the putative mouse hepatitis virus RNA-dependent RNA polymerase.

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12 December 2020

Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase

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12 December 2020

Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus Avian infectious bronchitis virus and characterization of the cleavage products

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12 December 2020

Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication

1 reference

12 December 2020

The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.

1 reference

12 December 2020

Identification of mouse hepatitis virus papain-like proteinase 2 activity

1 reference

12 December 2020

Big nidovirus genome. When count and order of domains matter.

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12 December 2020

Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

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12 December 2020

Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice

1 reference

12 December 2020

Selective replication of coronavirus genomes that express nucleocapsid protein

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12 December 2020

Nidovirales: a new order comprising Coronaviridae and Arteriviridae

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12 December 2020

Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

1 reference

12 December 2020

ADP-ribose-1"-monophosphatase: a conserved coronavirus enzyme that is dispensable for viral replication in tissue culture

1 reference

12 December 2020

Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5'-triphosphatase activities

1 reference

12 December 2020

Characterization of the two overlapping papain-like proteinase domains encoded in gene 1 of the coronavirus infectious bronchitis virus and determination of the C-terminal cleavage site of an 87-kDa protein

1 reference

12 December 2020

Molecular biology of severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses

1 reference

12 December 2020

Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors

1 reference

12 December 2020

The human coronavirus 229E superfamily 1 helicase has RNA and DNA duplex-unwinding activities with 5'-to-3' polarity

1 reference

12 December 2020

Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis.

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12 December 2020

The coronavirus replicase.

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12 December 2020

Expression, purification, and characterization of SARS coronavirus RNA polymerase.

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12 December 2020

Proteolytic processing at the amino terminus of human coronavirus 229E gene 1-encoded polyproteins: identification of a papain-like proteinase and its substrate.

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12 December 2020

Viral and cellular proteins involved in coronavirus replication.

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12 December 2020

A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae.

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12 December 2020

The predicted metal-binding region of the arterivirus helicase protein is involved in subgenomic mRNA synthesis, genome replication, and virion biogenesis.

1 reference

12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

12 December 2020

The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond.

1 reference

12 December 2020

Mechanisms and enzymes involved in SARS coronavirus genome expression

1 reference

12 December 2020

Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus.

1 reference

12 December 2020

Guanosine triphosphatase activity of the human coronavirus helicase

1 reference

12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Virus-encoded RNA helicases

1 reference

12 December 2020

The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.

1 reference

12 December 2020

Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication

1 reference

12 December 2020

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

1 reference

12 December 2020

A complex zinc finger controls the enzymatic activities of nidovirus helicases

1 reference

12 December 2020

Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition

1 reference

12 December 2020

The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor

1 reference

12 December 2020

Biochemical characterization of the equine arteritis virus helicase suggests a close functional relationship between arterivirus and coronavirus helicases

1 reference

12 December 2020

1 reference

12 December 2020

The carboxyl-terminal part of the putative Berne virus polymerase is expressed by ribosomal frameshifting and contains sequence motifs which indicate that toro- and coronaviruses are evolutionarily related

1 reference

12 December 2020

The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication

1 reference

12 December 2020

An 'elaborated' pseudoknot is required for high frequency frameshifting during translation of HCV 229E polymerase mRNA.

1 reference

12 December 2020

Identification of the mutations responsible for the phenotype of three MHV RNA-negative ts mutants

1 reference

12 December 2020

10.1007/978-0-387-33012-9_1

Identifiers

DOI

0 references

PMC publication ID

7123892

0 references

1 reference