(Q36642410)

English

5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor

scientific article published on 14 December 2012

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor (English)

1 reference

Europe PubMed Central

15 August 2017

1 reference

based on heuristic

inferred from title

author name string

Nagarekha Pasupuleti

1

1 reference

Europe PubMed Central

15 August 2017

Leonardo Leon

2

1 reference

Europe PubMed Central

15 August 2017

Kermit L Carraway

3

1 reference

Europe PubMed Central

15 August 2017

Fredric Gorin

4

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

14 December 2012

1 reference

Europe PubMed Central

15 August 2017

Journal of Pharmacology and Experimental Therapeutics

1 reference

Europe PubMed Central

15 August 2017

344

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Europe PubMed Central

15 August 2017

3

1 reference

Europe PubMed Central

15 August 2017

600-615

1 reference

Europe PubMed Central

15 August 2017

2-Amidino analogs of glycine-amiloride conjugates: inhibitors of urokinase-type plasminogen activator

1 reference

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Cancer therapy trials employing level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1.

1 reference

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The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion

1 reference

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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

1 reference

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Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas

1 reference

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30 September 2017

Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis.

1 reference

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AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

1 reference

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Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition

1 reference

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Human cancers converge at the HIF-2alpha oncogenic axis.

1 reference

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30 September 2017

The urokinase plasminogen activator system: a target for anti-cancer therapy.

1 reference

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30 September 2017

An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas

1 reference

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30 September 2017

Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas

1 reference

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30 September 2017

The roles of therapy-induced autophagy and necrosis in cancer treatment

1 reference

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30 September 2017

Central nervous system tumors

1 reference

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30 September 2017

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

1 reference

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30 September 2017

Cell death by necrosis: towards a molecular definition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Poly(ADP-ribose) (PAR) polymer is a death signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

1 reference

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30 September 2017

Amiloride peptide conjugates: prodrugs for sodium-proton exchange inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population

1 reference

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30 September 2017

The neurosurgeon as local oncologist: cellular and molecular neurosurgery in malignant glioma therapy

1 reference

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30 September 2017

Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

1 reference

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30 September 2017

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

1 reference

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30 September 2017

Na+ :H+ exchange inhibition induces intracellular acidosis and differentially impairs cell growth and viability of human and rat hepatocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Mitochondria and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Mitochondrial control of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

30 September 2017

Modulation of growth and radiochemosensitivity of human malignant glioma cells by acidosis

1 reference

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28 June 2018

A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

1 reference

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28 June 2018

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

20 September 2018

Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

20 September 2018

Perinecrotic glioma proliferation and metabolic profile within an intracerebral tumor xenograft

1 reference

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20 September 2018

Effects of amiloride on tumor growth and intracellular element content of tumor cells in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3583503

20 September 2018

Identifiers

10.1124/JPET.112.200519

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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