(Q36643636)

English

Target cell death triggered by cytotoxic T lymphocytes: a target cell mutant distinguishes passive pore formation and active cell suicide mechanisms

scientific article published on January 1994

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Target cell death triggered by cytotoxic T lymphocytes: a target cell mutant distinguishes passive pore formation and active cell suicide mechanisms (English)

1 reference

Europe PubMed Central

15 August 2017

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1 reference

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author name string

D S Ucker

1

1 reference

Europe PubMed Central

15 August 2017

J D Wilson

2

1 reference

Europe PubMed Central

15 August 2017

L D Hebshi

3

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Europe PubMed Central

15 August 2017

language of work or name

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publication date

1 January 1994

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Europe PubMed Central

15 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

15 August 2017

14

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Europe PubMed Central

15 August 2017

1

1 reference

Europe PubMed Central

15 August 2017

427-436

1 reference

Europe PubMed Central

15 August 2017

High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Cytolysis of nucleated cells by complement: cell death displays multi-hit characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Murine T lymphocyte clones with distinct immunological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Beta 2-microglobulin is not required for cell surface expression of the murine class I histocompatibility antigen H-2Db or of a truncated H-2Db

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Self-sparing of long-term in vitro-cloned or uncloned cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

High activity of N-alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine esterase and cytolytic perforin in cloned cell lines is not demonstrable in in-vivo-induced cytotoxic effector cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Hybrid antibodies can target sites for attack by T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Purified perforin induces target cell lysis but not DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Extracellular ATP in T-lymphocyte activation: possible role in effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Purification and characterization of cytolytic and noncytolytic human natural killer cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Death by suicide: one way to go in mammalian cellular development?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Evidence that glucocorticoid- and cyclic AMP-induced apoptotic pathways in lymphocytes share distal events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Susceptibility to cell death is a dominant phenotype: triggering of activation-driven T-cell death independent of the T-cell antigen receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Highly lytic in vivo primed cytolytic T lymphocytes devoid of lytic granules and BLT-esterase activity acquire these constituents in the presence of T cell growth factors upon blast transformation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

30 September 2017

Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Cell-mediated and glucocorticoid-mediated target cell lysis do not appear to share common pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Resistance of primary CD8+ cytotoxic T lymphocytes to lysis by cytotoxic granules from cloned T cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Cytolytic T-lymphocyte response to isolated class I H-2 proteins and influenza peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Evidence for multiple lytic pathways used by cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Expression of mRNAs for pore-forming protein and two serine esterases in murine primary and cloned effector lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Reversible cell damage by T-cell perforins. Calcium influx and propidium iodide uptake into K562 cells in the absence of lysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Differential effects of protein synthesis inhibition on CTL and targets in cell-mediated cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Subcellular localization of perforin and serine esterase in lymphokine-activated killer cells and cytotoxic T cells by immunogold labeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Free fatty acids are produced in and secreted from target cells very early in cytotoxic T lymphocyte-mediated killing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Differences between ATP-mediated cytotoxicity and cell-mediated cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Transfection of mouse cytotoxic T lymphocyte with an antisense granzyme A vector reduces lytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Poly-(ADP-ribose) polymerase partially contributes to target cell death triggered by cytolytic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Multiple cytolytic mechanisms displayed by activated human peripheral blood T cell subsets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

28 June 2018

Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

20 September 2018

Consequences of self-presentation of peptide antigen by cytolytic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358392

21 October 2018

Activation-driven T cell death. I. Requirements for de novo transcription and translation and association with genome fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic inhibitors distinguish cytolytic activity of CD4 and CD8 clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Responses of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell type-dependent lysis and DNA fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytolytic lymphocytes induce both apoptosis and necrosis in target cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peritoneal exudate lymphocyte and mixed lymphocyte culture hybridomas are cytolytic in the absence of cytotoxic cell proteinases and perforin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of an anti-H-2 monoclonal antibody and its use in large-scale antigen purification

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a "heteroclitic" cytotoxic lymphocyte clone: heterogeneity of receptors or signals?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NK and ADCC activity by antibodies against purified cytoplasmic granules from rat LGL tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of DNA degradation in target cells lysed by granules derived from cytolytic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic lymphocyte-derived lytic granules do not induce DNA fragmentation in target cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8264610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.14.1.427

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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