(Q36647435)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Genes, ageing and longevity in humans: problems, advantages and perspectives (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Fabiola Olivieri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Maurizio Cardelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Aurelia Santoro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Michele Mishto

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Francesco Lescai

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Giuseppe Paolisso

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Daniela Monti

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Salvioli S

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Marchegiani F

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Bellavista E

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Invidia L

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Valensin S

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Sevini F

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Cevenini E

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Celani L

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Gonos E

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Caruso C

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

De Benedictis G

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Franceschi C

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

1 reference

1 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

published in

Free Radical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1303-1323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090420%20AND%20SRC:MED&resulttype=core&format=json

Aging: a theory based on free radical and radiation chemistry

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Thematic review series: The immune system and atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The pathogenesis of atherosclerosis--an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

PON1 paraoxonase activity is reduced during HDL oxidation and is an indicator of HDL antioxidant capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

On the physiological role(s) of the paraoxonases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Paraoxonase activity and genotype predispose to successful aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Structural organization of the human PON1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The molecular basis of the human serum paraoxonase activity polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The PON1192RR genotype is associated with a higher prevalence of arterial hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic association analysis of human longevity in cohort studies of elderly subjects: an example of the PON1 gene in the Danish 1905 birth cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Study of factors influencing the decreased HDL associated PON1 activity with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic associations with human longevity at the APOE and ACE loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Unique lipoprotein phenotype and genotype associated with exceptional longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Apolipoprotein J: structure and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Polymorphisms in the human apolipoprotein-J/clusterin gene: ethnic variation and distribution in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Clusterin/apolipoprotein J in human aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Cloning and identification of genes that associate with mammalian replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Differential effects of clusterin/apolipoprotein J on cellular growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Advanced protein glycosylation induces transendothelial human monocyte chemotaxis and secretion of platelet-derived growth factor: role in vascular disease of diabetes and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Receptor-specific induction of insulin-like growth factor I in human monocytes by advanced glycosylation end product-modified proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Low insulin resistance and preserved beta-cell function contribute to human longevity but are not associated with TH-INS genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Endogenous hormones and carotid atherosclerosis in elderly men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mechanisms of life span determination in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Insulin/IGF signalling and ageing: seeing the bigger picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The endocrine regulation of aging by insulin-like signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

A conserved regulatory system for aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Array-based expression analysis of mouse liver genes: effect of age and of the longevity mutant Prop1df

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Reduced insulin/IGF-1 signalling and human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Reactive oxygen species-regulated signaling pathways in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: therapeutical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Reversible glutathionylation of complex I increases mitochondrial superoxide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Quantifying the relevance of different mediators in the human immune cell network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Transforming growth factor-beta1 down-regulates expression of chemokine stromal cell-derived factor-1: functional consequences in cell migration and adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Oxidative stress and advancing age: results in healthy centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Glucose regulation and oxidative stress in healthy centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Serum antioxidants, inflammation, and total mortality in older women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Serum IL-6 level and the development of disability in older persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Modest implication of interleukin-6 promoter polymorphisms in longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Interleukin 6-174 G/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Gender-specific association between -1082 IL-10 promoter polymorphism and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

IL-10 and TNF-alpha polymorphisms in a sample of Sicilian patients affected by tuberculosis: implication for ageing and life span expectancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype: effect of multiple gene interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Interleukin-6-174 G > C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genotypes and haplotypes in the IL-1 gene cluster: analysis of two genetically and diagnostically distinct groups of Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Superoxide dismutase evolution and life span regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Human copper-containing superoxide dismutase of high molecular weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The manganese superoxide dismutase gene of Drosophila: structure, expression, and evidence for regulation by MAP kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Low activity of superoxide dismutase and high activity of glutathione reductase in erythrocytes from centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Plasma antioxidants and longevity: a study on healthy centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Cellular resistance to homocysteine: a key for longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Reduced susceptibility to peroxidation of erythrocyte plasma membranes from centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Evidence for reduction of pro-atherosclerotic properties in platelets from healthy centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

21 January 2018

Glutathione transferases

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Glutathione S-transferase polymorphisms and survival from head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Physiology and pathophysiology of poly(ADP-ribosyl)ation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Poly(ADP-ribosyl)ation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Comparative characterisation of poly(ADP-ribose) polymerase-1 from two mammalian species with different life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

PARP-1: a regulator of genomic stability linked with mammalian longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Poly(ADP-Ribose) polymerase-1 in acute neuronal death and inflammation: a strategy for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Primary structure polymorphism at amino acid residue 72 of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Two polymorphic variants of wild-type p53 differ biochemically and biologically

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

p53 polymorphic variants at codon 72 exert different effects on cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Polymorphisms of H-ras-1 and p53 in breast cancer and lung cancer: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

P53 codon 72 polymorphism and longevity: additional data on centenarians from continental Italy and Sardinia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

p53 variants predisposing to cancer are present in healthy centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Variation in the human TP53 gene affects old age survival and cancer mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Oxidative damage and mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Role of nuclear background and in vivo environment in variable segregation behavior of the aging-dependent T414G mutation at critical control site for human fibroblast mtDNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The organization and inheritance of the mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA, aconitase 'wraps' it up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The mitochondrial theory of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Point mutations of the mtDNA control region in normal and neurodegenerative human brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Control region mtDNA variants: longevity, climatic adaptation, and a forensic conundrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA sequence variation in human evolution and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Effects of purifying and adaptive selection on regional variation in human mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA polymorphisms associated with longevity in a Finnish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Golden mean to longevity: rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Age dependent impact of LMP polymorphisms on TNFalpha-induced apoptosis in human peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Immunoproteasomes and immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Clinical phenotype of families with longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic contribution to biological aging: the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Parental longevity and mortality amongst Japanese men and women: the JACC Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Life-long sustained mortality advantage of siblings of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The network and the remodeling theories of aging: historical background and new perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The unusual genetics of human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

The interleukin-6 −174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Cardiovascular Advantages Among the Offspring of Centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Genetic Influence on Inflammation Variables in the Elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136

Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600917136