(Q36650046)

English

Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.

scientific article published on July 1993

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scholarly article

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Europe PubMed Central

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13 October 2019

Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles (English)

1 reference

Europe PubMed Central

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13 October 2019

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author name string

A H Kaplan

1

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13 October 2019

J A Zack

2

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13 October 2019

M Knigge

3

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13 October 2019

D A Paul

4

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13 October 2019

D J Kempf

5

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13 October 2019

D W Norbeck

6

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13 October 2019

R Swanstrom

7

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13 October 2019

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publication date

1 July 1993

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13 October 2019

Journal of Virology

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13 October 2019

67

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13 October 2019

4050-4055

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13 October 2019

7

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13 October 2019

A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins.

1 reference

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30 September 2017

Myristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virus

1 reference

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30 September 2017

Active human immunodeficiency virus protease is required for viral infectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237772

30 September 2017

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1 reference

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30 September 2017

Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity

1 reference

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30 September 2017

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

1 reference

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30 September 2017

Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity.

1 reference

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30 September 2017

Unmyristylated Moloney murine leukemia virus Pr65gag is excluded from virus assembly and maturation events

1 reference

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30 September 2017

A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation

1 reference

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30 September 2017

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1

1 reference

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30 September 2017

HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure

1 reference

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30 September 2017

An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection

1 reference

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30 September 2017

Structure-based, C2 symmetric inhibitors of HIV protease

1 reference

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30 September 2017

Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease

1 reference

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30 September 2017

Rational design of peptide-based HIV proteinase inhibitors

1 reference

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30 September 2017

Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments

1 reference

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30 September 2017

Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor

1 reference

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30 September 2017

Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237772

30 September 2017

Specific inhibitor of human immunodeficiency virus proteinase prevents the cytotoxic effects of a single-chain proteinase dimer and restores particle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237772

30 September 2017

Identification and characterization of human immunodeficiency virus type 1 gag-pol fusion protein in transfected mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237772

30 September 2017

Role of the gag polyprotein precursor in packaging and maturation of Rous sarcoma virus genomic RNA

1 reference

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30 September 2017

Properties of avian retrovirus particles defective in viral protease

1 reference

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30 September 2017

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

1 reference

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30 September 2017

Progression of early steps of human immunodeficiency virus type 1 replication in the presence of an inhibitor of viral protease

1 reference

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30 September 2017

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle

1 reference

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30 September 2017

Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins

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Immunological and chemical analysis of P6, the carboxyl-terminal fragment of HIV P15.

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The preparation and biochemical characterization of intact capsids of equine infectious anemia virus

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28 June 2018

Enzymatically active forms of reverse transcriptase of the human immunodeficiency virus

1 reference

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Murine leukemia virus maturation: protease region required for conversion from "immature" to "mature" core form and for virus infectivity

1 reference

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Analysis of non-infectious HIV particles produced in presence of HIV proteinase inhibitor

1 reference

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Characterization of an HIV-1 Isolate Displaying an Apparent Absence of Virion-Associated Reverse Transcriptase Activity

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Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.

1 reference

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Identification of protein intermediates in the processing of the p55 HIV-1 gag precursor in cells infected with recombinant vaccinia virus

1 reference

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20 September 2018

Identifiers

10.1128/JVI.67.7.4050-4055.1993

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8510215%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8510215%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

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