(Q36654010)

15 August 2017

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title

Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors (English)

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15 August 2017

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Kyle N Utecht

1

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15 August 2017

Jon J Hiles

series ordinal

2

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15 August 2017

Jill Kolesar

series ordinal

3

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15 August 2017

publication date

1 December 2006

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American Journal of Health-System Pharmacy

15 August 2017

published in

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15 August 2017

volume

63

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15 August 2017

issue

23

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15 August 2017

page(s)

2340-2348

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Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Adequate early cyclosporin exposure is critical to prevent renal allograft rejection: patients monitored by absorption profiling

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

The genetic determinants of the CYP3A5 polymorphism

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Genetic contribution to variable human CYP3A-mediated metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Identification of functionally variant MDR1 alleles among European Americans and African Americans

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Influence of CYP3A5 and MDR1 polymorphisms on tacrolimus concentration in the early stage after renal transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

The effect of variable CYP3A5 expression on cyclosporine dosing, blood pressure and long-term graft survival in renal transplant patients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

Single nucleotide polymorphism genotyping: biochemistry, protocol, cost and throughput

31 March 2020

1 reference

https://api.crossref.org/works/10.2146%2FAJHP060080

31 March 2020

Identifiers

DOI

10.2146/AJHP060080

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15 August 2017

1 reference