(Q36659847)

English

Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes

scientific article published on November 1993

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7902564%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7902564%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

1 reference

based on heuristic

inferred from title

0 references

Toshinori Nakayama

1

1 reference

Europe PubMed Central

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28 October 2019

author name string

D L Wiest

2

1 reference

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28 October 2019

K M Abraham

3

1 reference

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28 October 2019

T I Munitz

4

1 reference

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28 October 2019

R M Perlmutter

5

1 reference

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28 October 2019

A Singer

6

1 reference

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28 October 2019

language of work or name

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publication date

1 November 1993

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28 October 2019

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

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28 October 2019

90

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28 October 2019

22

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28 October 2019

10534-10538

1 reference

Europe PubMed Central

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28 October 2019

The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Identification of a monoclonal antibody specific for a murine T3 polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Molecular and cellular events of T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Short related sequences in the cytoplasmic domains of CD4 and CD8 mediate binding to the amino-terminal domain of the p56lck tyrosine protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Mice lacking MHC class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

30 September 2017

Engagement of the CD4 molecule influences cell surface expression of the T-cell receptor on thymocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

28 June 2018

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

28 June 2018

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

28 June 2018

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

28 June 2018

Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

28 June 2018

Peptide sequences of T-cell receptor δ and γ chains are identical to predicted X and γ proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47811

4 December 2018

Participation of CD4 coreceptor molecules in T-cell repertoire selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of CD8-dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7902564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.90.22.10534

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7902564%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

1993PNAS...9010534N

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7902564%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7902564%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

ResearchGate publication ID

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