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Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.
scientific article published on 4 January 2013
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
title
Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
main subject
autophagy
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cell line
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author
Sharon Tooze
series ordinal
3
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Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
author name string
Fiona McAlpine
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1
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Europe PubMed Central
PMC publication ID
3590256
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
Leon E Williamson
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2
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PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
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21 February 2020
Edmond Y W Chan
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4
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3590256
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
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21 February 2020
publication date
4 January 2013
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Europe PubMed Central
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3590256
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
published in
Autophagy
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stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
volume
9
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Europe PubMed Central
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3590256
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21 February 2020
issue
3
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PMC publication ID
3590256
reference URL
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retrieved
21 February 2020
page(s)
361-373
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Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
describes a project that uses
ULK1 KO MEF (SIM)
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ULK1 KO MEF (SV40)
0 references
ULK1/2 WT MEF (SIM)
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ULK1/2 WT MEF (SV40)
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ULK1+ULK2 DKO MEF (SIM)
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ULK1+ULK2 DKO MEF (SV40)
0 references
ULK2 KO MEF (SIM)
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ULK2 KO MEF (SV40)
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ImageJ
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Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3590256/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy
1 reference
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PubMed Central
reference URL
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30 September 2017
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy
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30 September 2017
Canonical and non-canonical autophagy: variations on a common theme of self-eating?
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30 September 2017
Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation.
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30 September 2017
Regulation and function of uncoordinated-51 like kinase proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.
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30 September 2017
Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy
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30 September 2017
The role of Atg proteins in autophagosome formation
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30 September 2017
ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
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30 September 2017
Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
1 reference
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PubMed Central
reference URL
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30 September 2017
Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.
1 reference
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PubMed Central
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30 September 2017
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
1 reference
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PubMed Central
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30 September 2017
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.
1 reference
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PubMed Central
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30 September 2017
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
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PubMed Central
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30 September 2017
Trafficking and signaling in mammalian autophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Membrane trafficking events that partake in autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Discovery of Atg5/Atg7-independent alternative macroautophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Atg101, a novel mammalian autophagy protein interacting with Atg13
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Evolution of Atg1 function and regulation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Autophagy mediates the mitotic senescence transition
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
The role of autophagy during the early neonatal starvation period
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Role of Unc51.1 and its binding partners in CNS axon outgrowth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
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30 September 2017
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
30 September 2017
The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590256
retrieved
20 September 2018
The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23291478
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/AUTO.23066
1 reference
stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PMC publication ID
3590256
1 reference
stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PubMed publication ID
23291478
1 reference
stated in
Europe PubMed Central
PMC publication ID
3590256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23291478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
ResearchGate publication ID
234067460
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