(Q36670602)

15 August 2017

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title

Creating a cardiac pacemaker by gene therapy (English)

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15 August 2017

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Traian M Anghel

1

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15 August 2017

Steven M Pogwizd

series ordinal

2

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15 August 2017

publication date

1 December 2006

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Medical & Biological Engineering & Computing

15 August 2017

published in

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15 August 2017

volume

45

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15 August 2017

issue

2

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15 August 2017

page(s)

145-155

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Gap junctional channels in adult mammalian sinus nodal cells. Immunolocalization and electrophysiology

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

Voltage‐clamp investigations of membrane currents underlying pace‐maker activity in rabbit sino‐atrial node

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

The pacemaker current in the sinus node

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

G proteins in the heart. A redundant and diverse transmembrane signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking: insights from stability and bifurcation analyses of a mathematical model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

Sustained inward current during pacemaker depolarization in mammalian sinoatrial node cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS11517-006-0135-0

21 January 2018

12 December 2020

Nomenclature of voltage-gated calcium channels.

1 reference

12 December 2020

Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs

1 reference

12 December 2020

Passive electrical properties of atrial fibers of the rabbit heart

1 reference

12 December 2020

Biological pacemaker implanted in canine left bundle branch provides ventricular escape rhythms that have physiologically acceptable rates

1 reference

12 December 2020

Mechanism of pacemaking in I(K1)-downregulated myocytes.

1 reference

12 December 2020

Does the "pacemaker current" generate the diastolic depolarization in the rabbit SA node cells?

1 reference

12 December 2020

Disturbed atrio-ventricular conduction and normal contractile function in isolated hearts from Cav1.3-knockout mice.

1 reference

12 December 2020

Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine Heart

1 reference

12 December 2020

Structure and mechanism of the G protein-coupled receptor kinases.

1 reference

12 December 2020

The sustained inward current in sino-atrial node cells of guinea-pig heart

1 reference

12 December 2020

Functional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activity

1 reference

12 December 2020

Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes

1 reference

12 December 2020

The sinoatrial node, a heterogeneous pacemaker structure

1 reference

12 December 2020

Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness

1 reference

12 December 2020

1 reference

12 December 2020

Heart failure hospitalization is more common in pacemaker patients with sinus node dysfunction and a prolonged paced QRS duration.

1 reference

12 December 2020

Membrane potential fluctuations resulting from submembrane Ca2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state

1 reference

12 December 2020

Molecular enhancement of porcine cardiac chronotropy

1 reference

12 December 2020

Cardiovascular gene therapy: angiogenesis and beyond

1 reference

12 December 2020

Rapidly and slowly activating components of delayed rectifier K(+) current in guinea-pig sino-atrial node pacemaker cells.

1 reference

12 December 2020

Reversal of potassium channel deficiency in cells from failing hearts by adenoviral gene transfer: a prototype for gene therapy for disorders of cardiac excitability and contractility

1 reference

12 December 2020

HCN2 overexpression in newborn and adult ventricular myocytes: distinct effects on gating and excitability

1 reference

12 December 2020

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

1 reference

12 December 2020

Pacemaker mechanisms in cardiac tissue.

1 reference

12 December 2020

Permanent pacing is a risk factor for the development of heart failure

1 reference

12 December 2020

Removal of sialic acid alters both T- and L-type calcium currents in cardiac myocytes

1 reference

12 December 2020

Molecular cloning of multiple subtypes of a novel rat brain isoform of the α1 subunit of the voltage-dependent calcium channel

1 reference

12 December 2020

Dose dependent effects of cardiac beta2 adrenoceptor gene therapy

1 reference

12 December 2020

Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering.

1 reference

12 December 2020

Comparison of a calcium antagonist, CD-349, with nifedipine, diltiazem, and verapamil in rabbit spontaneously beating sinoatrial node cells

1 reference

12 December 2020

Impact of transforming growth factor-beta1 on atrioventricular node conduction modification by injected autologous fibroblasts in the canine heart

1 reference

12 December 2020

Prospects for genetic manipulation of cardiac excitability.

1 reference

12 December 2020

Existence of a low-threshold and sustained inward current in rabbit atrio-ventricular node cells

1 reference

12 December 2020

Transplanted neonatal cardiomyocytes as a potential biological pacemaker in pigs with complete atrioventricular block.

1 reference

12 December 2020

Inactivation properties of T-type calcium current in canine cardiac Purkinje cells

1 reference

12 December 2020

Phosphatase inhibition by calyculin A increases i(f) in canine Purkinje fibers and myocytes

1 reference

12 December 2020

Rhythmic Ca2+ oscillations drive sinoatrial nodal cell pacemaker function to make the heart tick.

1 reference

12 December 2020

Pacemaker mechanism of mammalian sinoatrial node cells

1 reference

12 December 2020

Human mesenchymal stem cells as a gene delivery system to create cardiac pacemakers

1 reference

12 December 2020

Virus-mediated modification of cellular excitability

1 reference

12 December 2020

Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels

1 reference

12 December 2020

Regional differences in the role of the Ca2+ and Na+ currents in pacemaker activity in the sinoatrial node.

1 reference

12 December 2020

Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation

1 reference

12 December 2020

Serious workings of the funny current.

1 reference

12 December 2020

Modification of cellular communication by gene transfer

1 reference

12 December 2020

Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: role of the immune response

1 reference

12 December 2020

Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process.

1 reference

12 December 2020

Contribution of L-type Ca2+ current to electrical activity in sinoatrial nodal myocytes of rabbits

1 reference

12 December 2020

Biological pacemaker created by gene transfer

1 reference

12 December 2020

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

1 reference

12 December 2020

[Electrophysiological properties of stem cells]

1 reference

12 December 2020

Propagation through electrically coupled cells. How a small SA node drives a large atrium

1 reference

12 December 2020

Immunohistochemical delineation of the conduction system. I: The sinoatrial node

1 reference

12 December 2020

Facilitation of the L-type calcium current in rabbit sino-atrial cells: effect on cardiac automaticity

1 reference

12 December 2020

Expression and function of a biological pacemaker in canine heart

1 reference

12 December 2020

Focal modification of electrical conduction in the heart by viral gene transfer

1 reference

12 December 2020

Synchronous occurrence of spontaneous localized calcium release from the sarcoplasmic reticulum generates action potentials in rat cardiac ventricular myocytes at normal resting membrane potential

1 reference

12 December 2020

MiRP1 modulates HCN2 channel expression and gating in cardiac myocytes

1 reference

12 December 2020

15th annual Gordon K. Moe Lecture. Biological pacemaking: in our lifetime?

1 reference

12 December 2020

Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart

1 reference

12 December 2020

Functional Roles of Ca(v)1.3 (alpha(1D)) calcium channel in sinoatrial nodes: insight gained using gene-targeted null mutant mice

1 reference

12 December 2020

Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

1 reference

12 December 2020

Human mesenchymal stem cells make cardiac connexins and form functional gap junctions

1 reference

12 December 2020

Biological pacemaker created by fetal cardiomyocyte transplantation

1 reference

12 December 2020

Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes

1 reference

12 December 2020

Association of prolonged QRS duration with death in a clinical trial of pacemaker therapy for sinus node dysfunction.

1 reference

12 December 2020

Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver). A novel strategy for modifying excitability

1 reference

12 December 2020

Enhancement of murine cardiac chronotropy by the molecular transfer of the human beta2 adrenergic receptor cDNA.

1 reference

12 December 2020

Sino-atrial nodal cells of mammalian hearts: ionic currents and gene expression of pacemaker ionic channels

1 reference

12 December 2020

Characteristics of L- and T-type Ca2+ currents in canine cardiac Purkinje cells

1 reference

12 December 2020

Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells

1 reference

12 December 2020

Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers

1 reference

12 December 2020

Ionic basis of the chronotropic effect of acetylcholine on the rabbit sinoatrial node

1 reference

12 December 2020

ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antirrhythmia Devices: Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committe

1 reference

12 December 2020

Gene therapy for cardiac arrhythmias.

1 reference

12 December 2020

The emergence of a general theory of the initiation and strength of the heartbeat

1 reference

12 December 2020

Electrophysiological properties of human mesenchymal stem cells

1 reference

12 December 2020

Review of Early Pacemaker Development

1 reference

12 December 2020

Fibroblasts can be genetically modified to produce excitable cells capable of electrical coupling.

1 reference

12 December 2020

Spatial and functional relationship between myocytes and fibroblasts in the rabbit sinoatrial node

1 reference

12 December 2020

Stem cell-derived cardiomyocytes demonstrate arrhythmic potential

1 reference

12 December 2020

Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance

1 reference

12 December 2020

10.1007/S11517-006-0135-0

Identifiers

DOI

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15 August 2017

DBLP publication ID

journals/mbec/AnghelP07

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DBLP Dataset 2021-01-02

28 January 2021

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