(Q36671633)

English

Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome P450 3A4 substrate, in patients with chronic myeloid leukaemia

scientific article published on November 17, 2003

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia (English)

1 reference

Europe PubMed Central

15 August 2017

Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome P450 3A4 substrate, in patients with chronic myeloid leukaemia (English)

1 reference

10.1038/SJ.BJC.6601152

https://api.crossref.org/works/10.1038/SJ.BJC.6601152

31 March 2024

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

10.1038/SJ.BJC.6601152

https://api.crossref.org/works/10.1038/SJ.BJC.6601152

31 March 2024

author name string

S. G. O'Brien

1

1 reference

Europe PubMed Central

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31 March 2024

P. Meinhardt

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

E. Bond

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

J. Beck

4

1 reference

Europe PubMed Central

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31 March 2024

B. Peng

5

1 reference

Europe PubMed Central

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31 March 2024

C. Dutreix

6

1 reference

Europe PubMed Central

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31 March 2024

G. Mehring

7

1 reference

Europe PubMed Central

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31 March 2024

S. Milosavljev

8

1 reference

Europe PubMed Central

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31 March 2024

C. Huber

9

1 reference

Europe PubMed Central

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31 March 2024

R. Capdeville

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

T. Fischer

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

language of work or name

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publication date

1 November 2003

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Europe PubMed Central

15 August 2017

17 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14612892

31 March 2024

full work available at URL

https://doi.org/10.1038/sj.bjc.6601152

online access status

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Europe PubMed Central

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31 March 2024

https://europepmc.org/articles/PMC2394453

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

https://europepmc.org/articles/PMC2394453?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612892

31 March 2024

http://www.nature.com/articles/6601152.pdf

Portable Document Format

1 reference

10.1038/SJ.BJC.6601152

https://api.crossref.org/works/10.1038/SJ.BJC.6601152

31 March 2024

http://www.nature.com/articles/6601152

1 reference

10.1038/SJ.BJC.6601152

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31 March 2024

British Journal of Cancer

1 reference

Europe PubMed Central

15 August 2017

89

1 reference

Europe PubMed Central

15 August 2017

1855-1859

1 reference

Europe PubMed Central

15 August 2017

10

1 reference

Europe PubMed Central

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601152

0 references

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

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30 September 2017

A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias

1 reference

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30 September 2017

ARG tyrosine kinase activity is inhibited by STI571.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

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30 September 2017

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

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30 September 2017

Drug-grapefruit juice interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors

1 reference

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30 September 2017

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

Simvastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia

1 reference

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30 September 2017

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

1 reference

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30 September 2017

Rhabdomyolysis with simvastatin use

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394453

30 September 2017

In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase

1 reference

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30 September 2017

HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies

1 reference

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30 September 2017

Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

1 reference

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30 September 2017

Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

1 reference

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28 June 2018

Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.

1 reference

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20 September 2018

Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study

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20 September 2018

[Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of the hepatic cytochrome P450 enzyme system activity]

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612892

12 December 2020

based on heuristic

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Phenytoin--allopurinol interaction: Michaelis--Menten kinetic parameters of phenytoin with and without allopurinol in a child with Lesch--Nyhan syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin: the clinical profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schweizerische medizinische Wochenschrift

18

125

1342

author name string

C Meier

publication date

1995

1 reference

10.1038/SJ.BJC.6601152

https://api.crossref.org/works/10.1038/SJ.BJC.6601152

31 March 2024

Drug Metabolism and Disposition

22

25

1191

author name string

T Prueksaritanont

publication date

1997

1 reference

10.1038/SJ.BJC.6601152

https://api.crossref.org/works/10.1038/SJ.BJC.6601152

31 March 2024

Drug Metabolism and Disposition

25

25

1228

author name string

P Schmiedlin-Ren

publication date

1997

1 reference

10.1038/SJ.BJC.6601152

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Drug Metabolism and Disposition

31

18

476

author name string

S Vickers

publication date

1990

1 reference

10.1038/SJ.BJC.6601152

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31 March 2024

Identifiers

10.1038/SJ.BJC.6601152

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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