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Acutely dysregulated, chronically disabled by the enemy within: T-cell responses to HIV-1 infection.
scientific article published on 5 December 2006
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Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
review article
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title
Acutely dysregulated, chronically disabled by the enemy within: T-cell responses to HIV-1 infection
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
main subject
disability
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author
Cynthia Mee Ling Munier
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
author name string
A D Kelleher
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2
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Europe PubMed Central
PubMed ID
17146463
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22 December 2019
publication date
5 December 2006
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Europe PubMed Central
PubMed ID
17146463
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22 December 2019
published in
Immunology & Cell Biology
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Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
volume
85
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Europe PubMed Central
PubMed ID
17146463
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
page(s)
6-15
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Europe PubMed Central
PubMed ID
17146463
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
issue
1
1 reference
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Europe PubMed Central
PubMed ID
17146463
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retrieved
22 December 2019
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Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/ L in HIV Type 1--Infected Individuals Receiving Potent Antiretroviral Therapy
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Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia
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Peripheral blood mononuclear cell abnormalities and their relationship to clinical course in homosexual men with HIV infection
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Effects of primary HIV-1 infection on subsets of CD4+ and CD8+ T lymphocytes
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Increased losses of CD4+CD45RA+ cells in late stages of HIV infection is related to increased risk of death: evidence from a cohort of 347 HIV-infected individuals.
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7 January 2021
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Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals
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7 January 2021
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HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
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7 January 2021
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Identification of a major co-receptor for primary isolates of HIV-1
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7 January 2021
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The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
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7 January 2021
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A model of primary HIV-1 infection.
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Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy
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7 January 2021
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HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies
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T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS.
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Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection
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Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
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7 January 2021
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Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
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7 January 2021
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Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir
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7 January 2021
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Immune reconstitution after highly active anti-retroviral treatment of HIV infection.
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7 January 2021
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Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
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7 January 2021
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Restoration of the immune system with anti-retroviral therapy
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7 January 2021
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Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age.
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7 January 2021
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Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection.
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7 January 2021
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CD4+ and CD8+ T cell receptor repertoire perturbations with normal levels of T cell receptor excision circles in HIV-infected, therapy-naive adolescents.
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7 January 2021
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Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children
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7 January 2021
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T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy
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Longitudinal changes in CD4+ T cell antigen receptor diversity and naive/memory cell phenotype during 9 to 26 months of antiretroviral therapy of HIV-infected patients.
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Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
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7 January 2021
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T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Relative significance of different pathways of immune reconstitution in HIV type 1 infection as estimated by mathematical modeling.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Naïve T Cells Are Maintained in the Periphery During the First3 Months of Acute HIV-1 Infection: Implications for Analysis of Thymus Function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in thymic function with age and during the treatment of HIV infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
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Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Quantification of thymic function by measuring T cell receptor excision circles within peripheral blood and lymphoid tissues in monkeys
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
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Identification of a human recent thymic emigrant phenotype
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7 January 2021
based on heuristic
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IL-7 is critical for homeostatic proliferation and survival of naive T cells
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reference URL
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7 January 2021
based on heuristic
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Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
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7 January 2021
based on heuristic
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Expression of CD31 epitopes on human lymphocytes: CD31 monoclonal antibodies differentiate between naive (CD45RA+) and memory (CD45RA-) CD4-positive T cells
1 reference
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7 January 2021
based on heuristic
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Distinct Mechanisms of T Cell Reconstitution Can Be Identified by Estimating Thymic Volume in Adult HIV‐1 Disease
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reference URL
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7 January 2021
based on heuristic
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Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of IL-7Ralpha is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection as measured by Ki-67 antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell subset alterations in HIV-infected homosexual men: NIAID Multicenter AIDS cohort study
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
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Programmed cell death in HIV infection: dysregulation of BCL-2 and Fas pathways and contribution to AIDS pathogenesis
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
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inferred from DOI database lookup
Nonproliferating bystander CD4+ T cells lacking activation markers support HIV replication during immune activation
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
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7 January 2021
based on heuristic
inferred from DOI database lookup
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ lymphocyte function with early human immunodeficiency virus infection
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition
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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of CD4+ T cell proliferative ability but not loss of human immunodeficiency virus type 1 specificity equates with progression to disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune control of HIV-1 after early treatment of acute infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cells that proliferate in vitro detected in samples from most viremic subjects and inversely associated with plasma HIV-1 levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of sustained HIV-1 plasma viremia on HIV-1 Gag-specific CD4+ T cell maturation and function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early induction and maintenance of Env-specific T-helper cells following human immunodeficiency virus type 1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A prospective trial of structured treatment interruptions in human immunodeficiency virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early proliferation of CCR5(+) CD38(+++) antigen-specific CD4(+) Th1 effector cells during primary HIV-1 infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD127+CCR5+CD38+++ CD4+ Th1 effector cells are an early component of the primary immune response to vaccinia virus and precede development of interleukin-2+ memory CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV preferentially infects HIV-specific CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular immune responses to HIV.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Skewed maturation of memory HIV-specific CD8 T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral immune evasion due to persistence of activated T cells without effector function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restoring function in exhausted CD8 T cells during chronic viral infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency and function of HIV-specific CD8(+) T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigenic oscillations and shifting immunodominance in HIV-1 infections.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolution and transmission of stable CTL escape mutations in HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune restoration disease after antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytomegalovirus (CMV) Retinitis Immune Restoration Disease Occurs during Highly Active Antiretroviral Therapy–Induced Restoration of CMV‐Specific Immune Responses within a Predominant Th2 Cytokine Environment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Levels of IL-6 and soluble IL-6 receptor are increased in HIV patients with a history of immune restoration disease after HAART
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plasma bioavailable interleukin-6 is elevated in human immunodeficiency virus-infected patients who experience herpesvirus-associated immune restoration disease after start of highly active antiretroviral therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of thymic regeneration in mice and humans following androgen blockade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ICB.7100015
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ICB.7100015
1 reference
stated in
Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
PubMed ID
17146463
1 reference
stated in
Europe PubMed Central
PubMed ID
17146463
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17146463%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 December 2019
ResearchGate publication ID
6653547
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