(Q36679348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

review article

1 reference

title

Molecular and cellular pathogenesis of autosomal recessive polycystic kidney disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

autosomal recessive polycystic kidney

22 December 2019

main subject

0 references

author

Luiz F Onuchic

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

L F Menezes

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

language of work or name

English

0 references

publication date

1 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

Brazilian Journal of Medical and Biological Research

22 December 2019

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

page(s)

1537-1548

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17160262%20AND%20SRC:MED&resulttype=core&format=json

Autosomal Recessive Polycystic Kidney Disease: The Clinical Experience in North America

22 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Comprehensive genomic analysis of PKHD1 mutations in ARPKD cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Congenital diseases of intrahepatic bile ducts: variations on the theme "ductal plate malformation"

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Spectrum of mutations in the gene for autosomal recessive polycystic kidney disease (ARPKD/PKHD1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

A physiological view of the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Bending the MDCK cell primary cilium increases intracellular calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Defective planar cell polarity in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

A transcriptional network in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

A role for ERK1/2 in EGF- and ATP-dependent regulation of amiloride-sensitive sodium absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Na transport in autosomal recessive polycystic kidney disease (ARPKD) cyst lining epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Clinical consequences of PKHD1 mutations in 164 patients with autosomal-recessive polycystic kidney disease (ARPKD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004

Milder Presentation of Recessive Polycystic Kidney Disease Requires Presence of Amino Acid Substitution Mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006001200004