(Q36685114)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Robert H C Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sabine Wislet-Gendebien

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Filsy Samuel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Gang Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Diana Marsilio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Tammy Langman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Paul E Fraser

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Anurag Tandon

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

23 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

11

1 reference

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22 February 2020

page(s)

7438-7449

1 reference

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describes a project that uses

22 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3597785/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

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Alpha-synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis

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Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells

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Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs

30 September 2017

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Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis

30 September 2017

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Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein

30 September 2017

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Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

30 September 2017

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Regulation of secretory vesicle traffic by Rab small GTPases

30 September 2017

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

30 September 2017

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30 September 2017

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

30 September 2017

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

30 September 2017

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30 September 2017

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The structural and mechanistic basis for recycling of Rab proteins between membrane compartments.

30 September 2017

1 reference

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Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.

30 September 2017

1 reference

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Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

30 September 2017

1 reference

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The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.

30 September 2017

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The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation

30 September 2017

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Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain

30 September 2017

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Geranylgeranyl switching regulates GDI-Rab GTPase recycling

30 September 2017

1 reference

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Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex

30 September 2017

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

30 September 2017

1 reference

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Evidence that alpha-synuclein functions as a negative regulator of Ca(++)-dependent alpha-granule release from human platelets

30 September 2017

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Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion

30 September 2017

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A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling

30 September 2017

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Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

30 September 2017

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

30 September 2017

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

30 September 2017

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Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

30 September 2017

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

30 September 2017

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

30 September 2017

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Structure and mutational analysis of Rab GDP-dissociation inhibitor

30 September 2017

1 reference

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Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor.

30 September 2017

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C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Isoprenoid modification of rab proteins terminating in CC or CXC motifs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Amino acid residues in the Ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Molecular dissection of guanine nucleotide dissociation inhibitor function in vivo. Rab-independent binding to membranes and role of Rab recycling factors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

The geranylgeranyl moiety but not the methyl moiety of the smg-25A/rab3A protein is essential for the interactions with membrane and its inhibitory GDP/GTP exchange protein

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Neural activity controls the synaptic accumulation of alpha-synuclein.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

A combinatorial code for the interaction of alpha-synuclein with membranes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Alpha-synuclein binding to rab3a in multiple system atrophy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

A complete genetic analysis of neuronal Rab3 function.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Membrane binding and self-association of alpha-synucleins.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Conformational properties of alpha-synuclein in its free and lipid-associated states

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597785

Use of Hsp90 inhibitors to disrupt GDI-dependent Rab recycling

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23344955

12 December 2020

inferred from PubMed ID database lookup

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23344955

12 December 2020

inferred from PubMed ID database lookup

alpha-Synuclein membrane interactions and lipid specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23344955

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M112.439497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23344955%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23344955

1 reference