(Q36691070)

15 August 2017

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title

The natural history of cervical HPV infection: unresolved issues (English)

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15 August 2017

Ciaran B J Woodman

1

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15 August 2017

Stuart I Collins

series ordinal

2

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15 August 2017

Lawrence S Young

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 January 2007

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15 August 2017

Nature Reviews Cancer

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15 August 2017

7

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15 August 2017

11-22

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15 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrc2050

15 August 2017

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cites work

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Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma

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Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers

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31 March 2020

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Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study.

31 March 2020

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Clearance of HPV infection in middle aged men and women after 9 years' follow up.

31 March 2020

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Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia

31 March 2020

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Concurrent and sequential acquisition of different genital human papillomavirus types

31 March 2020

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A prospective study of human papillomavirus (HPV) type 16 DNA detection by polymerase chain reaction and its association with acquisition and persistence of other HPV types

31 March 2020

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Cervical Coinfection with Human Papillomavirus (HPV) Types as a Predictor of Acquisition and Persistence of HPV Infection

31 March 2020

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Risk factors for subsequent cervicovaginal human papillomavirus (HPV) infection and the protective role of antibodies to HPV-16 virus-like particles.

31 March 2020

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A longitudinal study of genital human papillomavirus infection in a cohort of closely followed adolescent women

31 March 2020

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Cervical Coinfection with Human Papillomavirus (HPV) Types and Possible Implications for the Prevention of Cervical Cancer by HPV Vaccines

31 March 2020

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31 March 2020

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Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis

31 March 2020

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31 March 2020

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Chapter 13: Current findings from prophylactic HPV vaccine trials

31 March 2020

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A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection

31 March 2020

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Human papillomavirus infection is transient in young women: a population-based cohort study

31 March 2020

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Natural history of cervicovaginal papillomavirus infection in young women.

31 March 2020

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Detection of human papillomavirus DNA in cytologically normal women and subsequent cervical squamous intraepithelial lesions

31 March 2020

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Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: a prospective study

31 March 2020

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Type-specific persistence of human papillomavirus DNA before the development of invasive cervical cancer

31 March 2020

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Human papillomavirus detection by the hybrid capture II assay: a reliable test to select women with normal cervical smears at risk for developing cervical lesions

31 March 2020

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A population-based five-year follow-up study of cervical human papillomavirus infection

31 March 2020

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High risk human papillomavirus in women with normal cervical cytology prior to the development of abnormal cytology and colposcopy

31 March 2020

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Prevalence, incidence, and type-specific persistence of human papillomavirus in human immunodeficiency virus (HIV)-positive and HIV-negative women

31 March 2020

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Risk of invasive cervical cancer associated with polymorphic HLA DR/DQ haplotypes

31 March 2020

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Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study

31 March 2020

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Human papillomavirus and the long-term risk of cervical neoplasia

31 March 2020

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Human papillomavirus 16 load in normal and abnormal cervical scrapes: an indicator of CIN II/III and viral clearance

31 March 2020

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HPV infection and number of lifetime sexual partners are strong predictors for 'natural' regression of CIN 2 and 3.

31 March 2020

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Dietary intake and risk of persistent human papillomavirus (HPV) infection: the Ludwig-McGill HPV Natural History Study

31 March 2020

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Human papillomavirus type specific DNA and RNA persistence--implications for cervical disease progression and monitoring

31 March 2020

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Cervical HPV infection and neoplasia in a large population-based prospective study: the Manchester cohort

31 March 2020

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Folate is associated with the natural history of high-risk human papillomaviruses

31 March 2020

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Determination of Human Papillomavirus (HPV) Load and Type in High-Grade Cervical Lesions Surgically Resected from HIV-Infected Women during Follow-up of HPV Infection

31 March 2020

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Risks for incident human papillomavirus infection and low-grade squamous intraepithelial lesion development in young females

31 March 2020

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A critique of cohort studies examining the role of human papillomavirus infection in cervical neoplasia

31 March 2020

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Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students

31 March 2020

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Human papillomavirus DNA detection in cervical specimens by hybrid capture: correlation with cytologic and histologic diagnoses of squamous intraepithelial lesions of the cervix

31 March 2020

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Human papillomavirus distribution in cervical tissues of different morphology as determined by hybrid capture assay and PCR

31 March 2020

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Viral characteristics of human papillomavirus infection and antioxidant levels as risk factors for cervical dysplasia

31 March 2020

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Dynamics of human papillomavirus infection between biopsy and excision of cervical intraepithelial neoplasia: results from the ZYC101a protocol

31 March 2020

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HPV DNA patterns and disease implications in the follow-up of patients treated for HPV16 high-grade carcinoma in situ

31 March 2020

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Amplification of human papillomavirus types 16 and 18 in invasive cervical cancer.

31 March 2020

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Progression from productive infection to integration and oncogenic transformation in human papillomavirus type 59-immortalized foreskin keratinocytes

31 March 2020

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Detection and quantitation of human papillomavirus type 16, 18 and 52 DNA in the peripheral blood of cervical cancer patients

31 March 2020

1 reference

Human papillomavirus type 18 and rapidly progressing cervical intraepithelial neoplasia

31 March 2020

1 reference

Relationships of human papillomavirus type, qualitative viral load, and age with cytologic abnormality.

31 March 2020

1 reference

Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis

31 March 2020

1 reference

Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN).

31 March 2020

1 reference

Integrated human papillomavirus type 16 is frequently found in cervical cancer precursors as demonstrated by a novel quantitative real-time PCR technique

31 March 2020

1 reference

Integration of human papillomavirus type 16 into cellular DNA of cervical carcinoma: preferential deletion of the E2 gene and invariable retention of the long control region and the E6/E7 open reading frames

31 March 2020

1 reference

HPV 16 DNA in normal and malignant cervical epithelium: implications for the aetiology and behaviour of cervical neoplasia

31 March 2020

1 reference

Human papillomavirus 16 DNA in cervical cancers and in lymph nodes of cervical cancer patients: a diagnostic marker for early metastases?

31 March 2020

1 reference

Both episomal and integrated forms of human papillomavirus type 16 are involved in invasive cervical cancers

31 March 2020

1 reference

In situ evidence for HPV 16, 18, 33 integration in cervical squamous cell cancer in Britain and South Africa.

31 March 2020

1 reference

Integration of human papillomavirus types 16 and 18 in cervical adenocarcinoma

31 March 2020

1 reference

Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions

31 March 2020

1 reference

Analysis of deletion of the integrated human papillomavirus 16 sequence in cervical cancer: a rapid multiplex polymerase chain reaction approach

31 March 2020

1 reference

Coexistence of episomal and integrated HPV16 DNA in squamous cell carcinoma of the cervix

31 March 2020

1 reference

Changes in the physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analysed by PCR.

31 March 2020

1 reference

Physical status and expression of HPV genes in cervical cancers.

31 March 2020

1 reference

Analysis of HPV16, 18, 31, and 35 DNA in pre-invasive and invasive lesions of the uterine cervix

31 March 2020

1 reference

Association of human papillomavirus type 16 integration in the E2 gene with poor disease-free survival from cervical cancer.

31 March 2020

1 reference

Disruption of the E1 and E2 reading frames of HPV 16 in cervical carcinoma is associated with poor prognosis.

31 March 2020

1 reference

Asian-american variants of human papillomavirus type 16 have extensive mutations in the E2 gene and are highly amplified in cervical carcinomas.

31 March 2020

1 reference

The integration of HPV-18 DNA in cervical carcinoma

31 March 2020

1 reference

The antibody response to HPV proteins and the genomic state of HPVs in patients with cervical cancer.

31 March 2020

1 reference

HPV-16 E2 gene disruption and sequence variation in CIN 3 lesions and invasive squamous cell carcinomas of the cervix: relation to numerical chromosome abnormalities.

31 March 2020

1 reference

Variation in the E2-binding domain of HPV 16 is associated with high-grade squamous intraepithelial lesions of the cervix

31 March 2020

1 reference

Physical status of the E2 human papilloma virus 16 viral gene in cervical preneoplastic and neoplastic lesions

31 March 2020

1 reference

Biotinyl-tyramide-based in situ hybridization signal patterns distinguish human papillomavirus type and grade of cervical intraepithelial neoplasia

31 March 2020

1 reference

Rapid and sensitive detection of physical status of human papillomavirus type 16 DNA by quantitative real-time PCR.

31 March 2020

1 reference

Sequence variation and physical state of human papillomavirus type 16 cervical cancer isolates from Australia and New Caledonia

31 March 2020

1 reference

HPV 16 detection in cervical lesions, physical state of viral DNA and changes in p53 gene.

31 March 2020

1 reference

Study of viral integration of HPV-16 in young patients with LSIL.

31 March 2020

1 reference

Human papillomavirus type 16 status in cervical carcinoma cell DNA assayed by multiplex PCR.

31 March 2020

1 reference

Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome

31 March 2020

1 reference

Physical state and expression of HPV DNA in benign and dysplastic cervical tissue: different levels of viral integration are correlated with lesion grade

31 March 2020

1 reference

Human papillomavirus 16 E6/E7 transcript and E2 gene status in patients with cervical neoplasia.

31 March 2020

1 reference

Human papillomavirus type 16 E2 and E6/E7 variants

31 March 2020

1 reference

Human papillomavirus type 16 integration in cervical carcinoma in situ and in invasive cervical cancer.

31 March 2020

1 reference

HPV16 E2 gene disruption and polymorphisms of E2 and LCR: some significant associations with cervical cancer in Indian women.

31 March 2020

1 reference

Detection of specific human papillomavirus types in paraffin-embedded sections of cervical carcinomas

31 March 2020

1 reference

Integrated human papillomavirus types 52 and 58 are infrequently found in cervical cancer, and high viral loads predict risk of cervical cancer

31 March 2020

1 reference

Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology

31 March 2020

1 reference

Clonal history of papillomavirus-induced dysplasia in the female lower genital tract

31 March 2020

1 reference

FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites

31 March 2020

1 reference

Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers

31 March 2020

1 reference

Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma.

31 March 2020

1 reference

Common fragile sites are preferential targets for HPV16 integrations in cervical tumors

31 March 2020

1 reference

Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13

31 March 2020

1 reference

The role of viral integration in the development of cervical cancer.

31 March 2020

1 reference

Characterization of viral-cellular fusion transcripts in a large series of HPV16 and 18 positive anogenital lesions

31 March 2020

1 reference

A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques.

31 March 2020

1 reference

Systematic review of genomic integration sites of human papillomavirus genomes in epithelial dysplasia and invasive cancer of the female lower genital tract

31 March 2020

1 reference

MYC activation associated with the integration of HPV DNA at the MYC locus in genital tumors

31 March 2020

1 reference

DNA aneuploidy and integration of human papillomavirus type 16 e6/e7 oncogenes in intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix uteri

31 March 2020

1 reference

Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response.

31 March 2020

1 reference

Human papillomavirus type 16 E2 protein has no effect on transcription from episomal viral DNA.

31 March 2020

1 reference

Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants.

31 March 2020

1 reference

Acquisition and persistence of human papillomavirus infection in younger men: a prospective follow-up study among Danish soldiers

31 March 2020

1 reference

Determinants of Prevalence, Acquisition, and Persistence of Human Papillomavirus in Healthy Mexican Military Men

31 March 2020

1 reference

Oncogenic human papillomavirus DNA loads in human immunodeficiency virus-positive women with high-grade cervical lesions are strongly elevated

31 March 2020

1 reference

Methylation Patterns of Papillomavirus DNA, Its Influence on E2 Function, and Implications in Viral Infection

31 March 2020

1 reference

The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation

31 March 2020

1 reference

Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia

31 March 2020

1 reference

Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression?

31 March 2020

1 reference

CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimens: genomic hypomethylation correlates with carcinogenic progression

31 March 2020

1 reference

Clonal selection for transcriptionally active viral oncogenes during progression to cancer.

31 March 2020

1 reference

Epigenetics provides a new generation of oncogenes and tumour-suppressor genes

31 March 2020

1 reference

Epstein-Barr virus in gastric adenocarcinomas: association with ethnicity and CDKN2A promoter methylation

31 March 2020

1 reference

p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma.

31 March 2020

1 reference

High-density methylation of p14ARF and p16INK4A in Epstein-Barr virus-associated gastric carcinoma

31 March 2020

1 reference

Promoter hypermethylation of E-cadherin and its abnormal expression in Epstein-Barr virus-associated gastric carcinoma

31 March 2020

1 reference

Epstein-Barr virus and p16INK4A methylation in squamous cell carcinoma and precancerous lesions of the cervix uteri

31 March 2020

1 reference

Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection.

31 March 2020

1 reference

CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus

31 March 2020

1 reference

Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma

31 March 2020

1 reference

Epigenetic instability and chromosomal instability in hepatocellular carcinoma

31 March 2020

1 reference

Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus

31 March 2020

1 reference

p73 is over-expressed in vulval cancer principally as the Delta 2 isoform

31 March 2020

1 reference

Epigenetic inactivation of theSFRP genes is associated with drinking, smoking and HPV in head and neck squamous cell carcinoma

31 March 2020

1 reference

Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy

31 March 2020

1 reference

Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix

31 March 2020

1 reference

The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases

31 March 2020

1 reference

Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1.

31 March 2020

1 reference

Epigenetic changes in virus-associated human cancers.

31 March 2020

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Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma

31 March 2020

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

31 March 2020

1 reference

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

31 March 2020

1 reference

Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway

31 March 2020

1 reference

Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression.

31 March 2020

1 reference

SOCS1 [corrected] inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein

31 March 2020

1 reference

DNA methylation profiling of cervical squamous intraepithelial lesions using liquid-based cytology specimens: an approach that utilizes receiver-operating characteristic analysis

31 March 2020

1 reference

Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylation

31 March 2020

1 reference

Human papillomavirus (HPV) DNA copy number is dependent on grade of cervical disease and HPV type

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of human papillomavirus transcription by the differentiation-dependent epithelial factor Epoc-1/skn-1a.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC2050

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Dimensions Publication ID

15 August 2017

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