(Q36702987)

English

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate

scientific article published on 31 March 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

based on heuristic

inferred from title

author name string

N P Dhammika Nanayakkara

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Arba L Ager

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Marilyn S Bartlett

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Vanessa Yardley

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Simon L Croft

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ikhlas A Khan

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

James D McChesney

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Larry A Walker

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

0 references

publication date

31 March 2008

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

52

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2130-2137

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

8-Aminoquinolines: future role as antiprotozoal drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Primaquine therapy for malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Primaquine-induced hemolytic anemia: susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Primaquine sensitivity. Glucose-6-phosphate dehydrogenase deficiency: an inborn error of metabolism of medical and biological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

In vitro activity of tafenoquine alone and in combination with artemisinin against Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

In vitro and in vivo models of Pneumocystis carinii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

8-aminoquinolines effective against Pneumocystis carinii in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Phase 2 efficacy trial of an oral 8-aminoquinoline (WR6026) for treatment of visceral leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Methemoglobinemia Provoked by Malarial Chemoprophylaxis in Vietnam

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Oxidants, oxidant drugs, and malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Studies on the mechanisms of oxidation in the erythrocyte by metabolites of primaquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

1 Antimalarial Activity of the 8-Aminoquinolines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Comparison of the Curative Antimalarial Activities and Toxicities of Primaquine and Its d and l Isomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

30 September 2017

Randomized trial of 3-dose regimens of tafenoquine (WR238605) versus low-dose primaquine for preventing Plasmodium vivax malaria relapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Relations among antimalarial drugs: results of studies with cycloguanil-, sulfone-, or chloroquine-resistant Plasmodium berghei in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Effects of nine synthetic putative metabolites of primaquine on activity of the hexose monophosphate shunt in intact human red blood cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Antimalarial activity and inhibition of monoamine oxidases A and B by exo-erythrocytic antimalarials. Optical isomers of primaquine, N-acylated congeners, primaquine metabolites and 5-phenoxy-substituted analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Primaquine is lethal for intracellular but not extracellular Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Clindamycin/primaquine for treatment of Pneumocystis carinii pneumonia in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

28 June 2018

Studies in the quinoline series; the preparation of some 8-(omega-alkylaminoalkylamino)-quinolines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

A phase II dose-ranging study of sitamaquine for the treatment of visceral leishmaniasis in India.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

A phase II dose-increasing study of sitamaquine for the treatment of visceral leishmaniasis in Kenya

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

Primaquine-induced hemolytic anemia: formation of free radicals in rat erythrocytes exposed to 6-methoxy-8-hydroxylaminoquinoline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

Methemoglobin reductase activity and in vitro sensitivity towards oxidant induced methemoglobinemia in swiss mice and beagle dogs erythrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

Phase 2 trial of WR6026, an orally administered 8-aminoquinoline, in the treatment of visceral leishmaniasis caused by Leishmania chagasi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

Antimalarials. 14. 5-(aryloxy)-4-methylprimaquine analogues. A highly effective series of blood and tissue schizonticidal agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

5 September 2018

Primaquine analogues that are potent anti-Trypanosoma cruzi agents in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2415774

4 December 2018

Susceptibility of glucose-6-phosphate dehydrogenase deficient red cells to primaquine enantiomers and two putative metabolites--I. Effect on reduced glutathione, methemoglobin content and release of hemoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin with primaquine for Pneumocystis carinii pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin/primaquine therapy and secondary prophylaxis against Pneumocystis carinii pneumonia in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effects of primaquine and primaquine metabolites on exoerythrocytic stages of Plasmodium berghei

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin and primaquine as primary treatment for mild and moderately severePneumocystis carinii pneumonia in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of intermittent dosage of 8-aminoquinolines for therapy or prophylaxis of Pneumocystis pneumonia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inoculated mouse model of Pneumocystis carinii infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antileishmanial activity of lepidines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships of putative primaquine metabolites causing methemoglobin formation in canine hemolysates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The disposition of primaquine in the isolated perfused rat liver. Stereoselective formation of the carboxylic acid metabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential Metabolism of the Enantiomers of Primaquine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primaquine-induced methemoglobinemia during treatment of Pneumocystis carinii pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin/primaquine versus trimethoprim-sulfamethoxazole as primary therapy for Pneumocystis carinii pneumonia in AIDS: a randomized, double-blind pilot trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Clindamycin-primaquine in the treatment of Pneumocystis carinii pneumonia]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin and Primaquine Therapy for Mild-to-Moderate Episodes of Pneumocystis carinii Pneumonia in Patients with AIDS: AIDS Clinical Trials Group 044

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to an absence of NAT genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00645-07

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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