(Q36704140)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion (English)

1 reference

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29 December 2019

3

1 reference

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29 December 2019

author name string

Zachary P Evans

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Justin D Ellett

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Rick G Schnellmann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Kenneth D Chavin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

17 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 December 2019

published in

1 reference

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29 December 2019

volume

283

1 reference

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29 December 2019

issue

13

1 reference

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29 December 2019

page(s)

8573-8579

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

Nonalcoholic Fatty liver disease and obesity

29 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Apoptosis and necrosis in the liver: a tale of two deaths?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Anti-endotoxin monoclonal antibodies are protective against hepatic ischemia/reperfusion injury in steatotic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Lipid metabolism in hepatic steatosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Fatty acid synthase blockade protects steatotic livers from warm ischemia reperfusion injury and transplantation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Nonalcoholic fatty liver disease: pathogenesis and the role of antioxidants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Superoxide activates mitochondrial uncoupling proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Etiopathogenesis of nonalcoholic steatohepatitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Use of fatty donor liver is associated with diminished early patient and graft survival.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

PPARalpha-mediated upregulation of uncoupling protein-2 switches cyanide-induced apoptosis to necrosis in primary cortical cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Enhancement of cyanide-induced mitochondrial dysfunction and cortical cell necrosis by uncoupling protein-2.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Steatotic liver allografts up-regulate UCP-2 expression and suffer necrosis in rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Impact of donor, recipient, and graft features on the development of primary dysfunction in liver transplants

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Regulation of cellular oncosis by uncoupling protein 2.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

Fat-storing cell abnormalities associated with endothelial cell damage after cold ischemic storage of rat liver in UW solution.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2417178

UW solution protects against reperfusion injury by inhibiting lipid peroxidation

5 September 2018

1 reference

12 December 2020

Lipid peroxidation of parenchymal hepatocytes during cold preservation and after reoxygenation in rats

1 reference

12 December 2020

The effect of graded steatosis on flow in the hepatic parenchymal microcirculation

1 reference

12 December 2020

Are parenchymal changes in early post-transplant biopsies related to preservation-reperfusion injury or rejection?

1 reference

12 December 2020

Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study

1 reference

12 December 2020

Mechanisms of ischemic injury are different in the steatotic and normal rat liver

1 reference

12 December 2020

Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

1 reference

12 December 2020

Steatotic liver transplantation in the mouse: a model of primary nonfunction

1 reference

12 December 2020

Mechanisms of t-butyl hydroperoxide-induced toxicity to rabbit renal proximal tubules

1 reference

12 December 2020

Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M706784200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086675%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

18086675

1 reference