(Q36704477)

15 August 2017

1 reference

title

Interleukin-18 genetics and inflammatory disease susceptibility (English)

1 reference

15 August 2017

Thompson SR

1

1 reference

PubMed ID

17215860

15 August 2017

Humphries SE

series ordinal

2

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15 August 2017

11 January 2007

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15 August 2017

1 reference

15 August 2017

8

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15 August 2017

2

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15 August 2017

91-99

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.gene.6364366

15 August 2017

0 references

cites work

IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

Lung function and long term exposure to air pollutants in Switzerland. Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) Team

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

Cardiovascular disease burden increases, NIH funding decreases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Atherosclerosis — An Inflammatory Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Immune mechanisms in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Inflammation and atherosclerosis: novel insights into plaque formation and destabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Cloning of a new cytokine that induces IFN-gamma production by T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Regulation of human IL-18 gene expression: interaction of PU.1 with GC-box binding protein is involved in human IL-18 expression in myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Purification and characterization of the human interleukin-18 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 regulates both Th1 and Th2 responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 activates NF-kappaB in murine T helper type 1 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association between interleukin-18 gene polymorphism 105A/C and asthma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL-18 gene polymorphisms affect IL-18 production capability by monocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Reduced transcriptional activity in individuals with IL-18 gene variants detected from functional but not association study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 and the risk of coronary heart disease in European men: the Prospective Epidemiological Study of Myocardial Infarction (PRIME).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Associations of serum IL-18 levels with carotid intima-media thickness

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin 18 in acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 promoter polymorphisms in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association between IL-18 gene promoter polymorphisms and CTLA-4 gene 49A/G polymorphism in Japanese patients with type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Analysis of Polymorphisms of the Interleukin-18 Gene in Type 1 Diabetes and Hardy-Weinberg Equilibrium Testing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: hint for genotyping error?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Re: "Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions"

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association of IL-18 promoter polymorphisms with predisposition to Type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL-18 in patients with multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Increased serum levels of interleukin-18 in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interferon-gamma-inducing activity of interleukin-18 in the joint with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima et al

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Single‐nucleotide polymorphisms of the interleukin‐18 gene promoter region in rheumatoid arthritis patients: protective effect of AA genotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association study of polymorphisms within interleukin-18 in juvenile idiopathic arthritis and bronchial asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL-18 might reflect disease activity in mild and moderate asthma exacerbation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Increased secretion of IL-18 in vitro by peripheral blood mononuclear cells of patients with bronchial asthma and atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 is elevated in the sera from patients with atopic dermatitis and from atopic dermatitis model mice, NC/Nga

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Expression of IL-18 mRNA and secretion of IL-18 are reduced in monocytes from patients with atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

SAPALDIA: Methods and participation in the cross-sectional part of the Swiss Study on Air Pollution and Lung Diseases in Adults

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Immunohistochemical and immuno-electron-microscopic detection of interferon-gamma-inducing factor ("interleukin-18") in mouse intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

IL18 polymorphism is associated with an increased risk of Crohn's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

The immunopathophysiology of acute graft-versus-host-disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Kinetics of interferon-gamma secretion and its regulatory factors in the early phase of acute graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Elevated interleukin (IL)-18 levels during acute graft-versus-host disease after allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Serum levels of soluble IL-2 receptor, IL-12, IL-18, and IFN-gamma in patients with acute graft-versus-host disease after allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Patient interleukin-18 GCG haplotype associates with improved survival and decreased transplant-related mortality after unrelated-donor bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364366

7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6364366

1 reference

15 August 2017

1 reference

PubMed ID

17215860