(Q36707796)

15 August 2017

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title

Cybrid models of mtDNA disease and transmission, from cells to mice (English)

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15 August 2017

Ian A Trounce

1

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15 August 2017

Carl A Pinkert

series ordinal

2

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15 August 2017

publication date

1 January 2007

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Current Topics in Developmental Biology

15 August 2017

published in

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15 August 2017

volume

77

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15 August 2017

page(s)

157-183

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An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA.

15 August 2017

cites work

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7 January 2021

Respiratory complex III is required to maintain complex I in mammalian mitochondria

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7 January 2021

The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme

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7 January 2021

Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria

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7 January 2021

Translocation of active mitochondria during hamster preimplantation embryo development studied by confocal laser scanning microscopy

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7 January 2021

Mitochondria in human offspring derived from ooplasmic transplantation

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7 January 2021

Mitochondrial distribution and function in oocytes and early embryos

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https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Rat strain differences in gluconeogenesis by isolated hepatocytes

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7 January 2021

Diabetes and nutrition: the mitochondrial part

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7 January 2021

Uniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution

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7 January 2021

Different nucleotide changes in the large rRNA gene of the mitochondrial DNA confer chloramphenicol resistance on two human cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA of chloramphenicol-resistant mouse cells contains a single nucleotide change in the region encoding the 3' end of the large ribosomal RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's hereditary optic neuropathy mitochondrial DNA mutation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cytoplasmic inheritance of chloramphenicol resistance in mouse tissue culture cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Xenomitochondrial embryonic stem cells and mice: modeling human mitochondrial biology and disease

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https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Maternally-inherited Leigh syndrome-related mutations bolster mitochondrial-mediated apoptosis

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https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial dynamics in mammals

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

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7 January 2021

In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Replication and Transcription of Vertebrate Mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Structure and function of the mitochondrial genome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

The influence of nuclear background on the biochemical expression of 3460 Leber's hereditary optic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Birth of infant after transfer of anucleate donor oocyte cytoplasm into recipient eggs.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA in mammalian reproduction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Fate of genetically marked mitochondrial DNA from spermatocytes microinjected into mouse zygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-Induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Ethidium bromide-induced loss of mitochondrial DNA from primary chicken embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Functional constraints of nuclear-mitochondrial DNA interactions in xenomitochondrial rodent cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Sequence of the intron and flanking exons of the mitochondrial 21S rRNA gene of yeast strains having different alleles at the ω and rib-1 loci

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Nutrient-gene interactions in mitochondrial function: vitamin A needs are increased in BHE/Cdb rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Maternal inheritance of human mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Paternal inheritance of mitochondrial DNA in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Lipid enrichment and fusion of mitochondrial inner membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Erwin Baur or Carl Correns: who really created the theory of plastid inheritance?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Identification of mitochondrial DNA species in interspecific cybrids and reconstituted cells using restriction endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Human mitochondria and mitochondrial genome function as a single dynamic cellular unit

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Accumulation of mtDNA with a mutation at position 3271 in tRNA(Leu)(UUR) gene introduced from a MELAS patient to HeLa cells lacking mtDNA results in progressive inhibition of mitochondrial respiratory function

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Eukaryotic genome evolution: rearrangement and coevolution of compartmentalized genetic information

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Transmitochondrial differences and varying levels of heteroplasmy in nuclear transfer cloned cattle.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Glycine-231 residue of the mouse mitochondrial protonmotive cytochrome b: mutation to aspartic acid deranges electron transport

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mutational analysis of the mouse mitochondrial cytochrome b gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Sequence analysis of mouse mitochondrial chloramphenicol-resistant mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial chloramphenicol-resistant mutants can have deficiencies in energy metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Developmental fate of mitochondria microinjected into murine zygotes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Isolation and microinjection of somatic cell-derived mitochondria and germline heteroplasmy in transmitochondrial mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Expanding the functional human mitochondrial DNA database by the establishment of primate xenomitochondrial cybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Development of Mitochondrial Gene Replacement Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Construction of heteroplasmic mice containing two mitochondrial DNA genotypes by micromanipulation of single-cell embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Comparative studies on lipogenesis and cholesterogenesis in lipemic BHE rats and normal wistar rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Transfer of chloramphenicol-resistant mitochondrial DNA into the chimeric mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Inheritance of a mitochondrial DNA defect and impaired glucose tolerance in BHE/Cdb rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Expression of Rattus norvegicus mtDNA in Mus musculus cells results in multiple respiratory chain defects

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Functional respiratory chain analyses in murid xenomitochondrial cybrids expose coevolutionary constraints of cytochrome b and nuclear subunits of complex III.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Production of homoplasmic xenomitochondrial mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA copy number in bovine oocytes and somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Decreased physical performance of congenic mice with mismatch between the nuclear and the mitochondrial genome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Complete replacement of mitochondrial DNA in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Active digestion of sperm mitochondrial DNA in single living sperm revealed by optical tweezers

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Assignment of two mitochondrially synthesized polypeptides to human mitochondrial DNA and their use in the study of intracellular mitochondrial interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Number of mitochondria and some properties of mitochondrial DNA in the mouse egg

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Production of transmitochondrial mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondria transfer into mouse ova by microinjection

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Effects of purifying and adaptive selection on regional variation in human mtDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Altered calcium homeostasis in cells transformed by mitochondria from individuals with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Ethidium bromide induced mutation of yeast mitochondria: complete transformation of cells into respiratory deficient non-chromosomal "petites"

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Sequence analysis of mitochondrial DNA in a mouse cell line resistant to chloramphenicol and oligomycin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

The genetics and pathology of oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Chloramphenicol-resistant mutants of human HeLa cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Origin and functional consequences of the complex I defect in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Dominant distribution of mitochondrial DNA from recipient oocytes in bovine embryos and offspring after nuclear transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial activity in response to serum starvation in bovine (Bos taurus) cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Microinjection of cytoplasm or mitochondria derived from somatic cells affects parthenogenetic development of murine oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Production of transmitochondrial mouse cell lines by cybrid rescue of rhodamine-6G pre-treated L-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Development and initial characterization of xenomitochondrial mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial diseases in man and mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mouse models for mitochondrial disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cytoplasmic transfer of chloramphenicol resistance in human tissue culture cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Cytoplasmic inheritance in mammalian tissue culture cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

A novel system for assigning the mode of inheritance in mitochondrial disorders using cybrids and rhodamine 6G.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Transformation of isolated mammalian mitochondria by bacterial conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Assessment of membrane potentials of mitochondrial populations in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Elimination of mitochondrial elements and improved viability in hybrid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Maternal inheritance of mitochondrial DNA during backcrossing of two species of mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2977006-5

7 January 2021

10.1016/S0070-2153(06)77006-5

Identifiers

DOI

1 reference

15 August 2017

1 reference