(Q36710748)

15 August 2017

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title

Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility (English)

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15 August 2017

Jessica R K Seifert

1

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PubMed ID

17230199

15 August 2017

Marek Mlodzik

series ordinal

2

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15 August 2017

1 February 2007

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15 August 2017

Nature Reviews Genetics

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15 August 2017

8

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15 August 2017

126-138

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15 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/nrg2042

15 August 2017

0 references

cites work

The genetic control of tissue polarity in Drosophila

1 reference

Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila

31 March 2020

1 reference

Planar signaling and morphogenesis in Drosophila

31 March 2020

1 reference

Planar cell polarization: an emerging model points in the right direction

31 March 2020

1 reference

Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

31 March 2020

1 reference

Frizzled signalling and cell polarisation in Drosophila and vertebrates

31 March 2020

1 reference

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

31 March 2020

1 reference

Convergent extension: the molecular control of polarized cell movement during embryonic development

31 March 2020

1 reference

Shaping the vertebrate body plan by polarized embryonic cell movements

31 March 2020

1 reference

Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?

31 March 2020

1 reference

The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila.

31 March 2020

1 reference

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division.

31 March 2020

1 reference

Wnt signals can function as positional cues in establishing cell polarity

31 March 2020

1 reference

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

31 March 2020

1 reference

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

31 March 2020

1 reference

Noncanonical Wnt signaling and neural polarity

31 March 2020

1 reference

Frizzled6 controls hair patterning in mice

31 March 2020

1 reference

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

31 March 2020

1 reference

Polycystic kidney disease: cell division without a c(l)ue?

31 March 2020

1 reference

The primary cilium as the cell's antenna: signaling at a sensory organelle

31 March 2020

1 reference

Mechanisms of convergence and extension by cell intercalation

31 March 2020

1 reference

Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels

31 March 2020

1 reference

Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning

31 March 2020

1 reference

Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding

31 March 2020

1 reference

Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling

31 March 2020

1 reference

Fidelity in planar cell polarity signalling.

31 March 2020

1 reference

Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing

31 March 2020

1 reference

Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins.

31 March 2020

1 reference

The cadherins fat and dachsous regulate dorsal/ventral signaling in the Drosophila eye.

31 March 2020

1 reference

Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression.

31 March 2020

1 reference

Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye.

31 March 2020

1 reference

The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification.

31 March 2020

1 reference

Multiple roles for four-jointed in planar polarity and limb patterning.

31 March 2020

1 reference

Cleavage and secretion is not required for Four-jointed function in Drosophila patterning.

31 March 2020

1 reference

The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor.

31 March 2020

1 reference

Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.

31 March 2020

1 reference

The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye.

31 March 2020

1 reference

Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.

31 March 2020

1 reference

Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing.

31 March 2020

1 reference

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling

31 March 2020

1 reference

The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye.

31 March 2020

1 reference

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

31 March 2020

1 reference

Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

31 March 2020

1 reference

Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila.

31 March 2020

1 reference

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

31 March 2020

1 reference

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

31 March 2020

1 reference

Dishevelled controls cell polarity during Xenopus gastrulation

31 March 2020

1 reference

PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements

31 March 2020

1 reference

Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

31 March 2020

1 reference

Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells

31 March 2020

1 reference

Mathematical modeling of planar cell polarity to understand domineering nonautonomy.

31 March 2020

1 reference

Cell interactions and planar polarity in the abdominal epidermis of Drosophila.

31 March 2020

1 reference

Establishment and maintenance of planar epithelial cell polarity by asymmetric cadherin bridges: a computer model.

31 March 2020

1 reference

CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila.

31 March 2020

1 reference

Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila.

31 March 2020

1 reference

The casein kinase I family: roles in morphogenesis

31 March 2020

1 reference

Trimeric G protein-dependent frizzled signaling in Drosophila.

31 March 2020

1 reference

XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation

31 March 2020

1 reference

Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development.

31 March 2020

1 reference

Egfr signalling defines a protective function for ommatidial orientation in the Drosophila eye.

31 March 2020

1 reference

Egfr signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6.

31 March 2020

1 reference

Vertebrate gastrulation: polarity genes control the matrix

31 March 2020

1 reference

Monopolar protrusive activity: a new morphogenic cell behavior in the neural plate dependent on vertical interactions with the mesoderm in Xenopus

31 March 2020

1 reference

On the convergent cell movements of gastrulation in Fundulus

31 March 2020

1 reference

Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation

31 March 2020

1 reference

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation.

31 March 2020

1 reference

Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements.

31 March 2020

1 reference

Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.

31 March 2020

1 reference

ARF proteins: roles in membrane traffic and beyond

31 March 2020

1 reference

Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk

31 March 2020

1 reference

Polarity determination in the Drosophila eye.

31 March 2020

1 reference

Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene

31 March 2020

1 reference

Scabrous controls ommatidial rotation in the Drosophila compound eye.

31 March 2020

1 reference

EGF signaling and ommatidial rotation in the Drosophila eye.

31 March 2020

1 reference

Cooperative activities of drosophila DE-cadherin and DN-cadherin regulate the cell motility process of ommatidial rotation.

31 March 2020

1 reference

Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway.

31 March 2020

1 reference

Shaping the zebrafish notochord

31 March 2020

1 reference

A new member of the frizzled family from Drosophila functions as a Wingless receptor

31 March 2020

1 reference

The Wnt signaling pathway in development and disease

31 March 2020

1 reference

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

31 March 2020

1 reference

Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations

31 March 2020

1 reference

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

31 March 2020

1 reference

Developmental compartments and planar polarity in Drosophila.

31 March 2020

1 reference

Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity

31 March 2020

1 reference

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

31 March 2020

1 reference

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

31 March 2020

1 reference

Signaling specificity by Frizzled receptors in Drosophila.

31 March 2020

1 reference

Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

31 March 2020

1 reference

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

31 March 2020

1 reference

Frizzled-3 is required for the development of major fiber tracts in the rostral CNS.

31 March 2020

1 reference

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

31 March 2020

1 reference

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal

31 March 2020

1 reference

Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.

31 March 2020

1 reference

Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish

31 March 2020

1 reference

The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs

31 March 2020

1 reference

31 March 2020

1 reference

Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

31 March 2020

1 reference

The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus

31 March 2020

1 reference

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.

31 March 2020

1 reference

The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization.

31 March 2020

1 reference

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

31 March 2020

1 reference

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

31 March 2020

1 reference

The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing

31 March 2020

1 reference

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

31 March 2020

1 reference

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.

31 March 2020

1 reference

The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension

31 March 2020

1 reference

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

31 March 2020

1 reference

Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins

31 March 2020

1 reference

The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis

31 March 2020

1 reference

Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells

31 March 2020

1 reference

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila

31 March 2020

1 reference

Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye.

31 March 2020

1 reference

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

31 March 2020

1 reference

The role of RhoA in tissue polarity and Frizzled signalling

31 March 2020

1 reference

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

31 March 2020

1 reference

Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation

31 March 2020

1 reference

The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton.

31 March 2020

1 reference

The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling.

31 March 2020

1 reference

Genetic analysis of cadherin function in animal morphogenesis

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG2042

1 reference

release_n2j3duhiw5behcixgtrz6lalmq

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/n2j3duhiw5behcixgtrz6lalmq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

17230199

1 reference

PubMed ID

17230199