(Q36712703)

15 August 2017

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title

Mitochondrial reactive oxygen species-mediated signaling in endothelial cells (English)

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15 August 2017

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reactive oxygen species

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David X Zhang

1

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PubMed ID

17237240

15 August 2017

David D Gutterman

series ordinal

2

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15 August 2017

19 January 2007

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American Journal of Physiology Heart and Circulatory Physiology

15 August 2017

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15 August 2017

292

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15 August 2017

5

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15 August 2017

H2023-31

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Hypoxic modulation of Ca2+ signaling in human venous endothelial cells. Multiple roles for reactive oxygen species

15 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Stretch-induced phosphorylation of focal adhesion kinase in endothelial cells: role of mitochondrial oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against cytochrome P450 2E1-dependent toxicity in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial dysfunction in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial integrity and function in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Focal adhesion kinase regulation by oxidative stress in different cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Rotenone inhibition of spindle microtubule assembly in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

The pathobiology of diabetic complications: a unifying mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Hyperoxia-induced reactive oxygen species formation in pulmonary capillary endothelial cells in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial free radical generation, oxidative stress, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial reactive oxygen species and Ca2+ signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Cellular oxygen sensing by mitochondria: old questions, new insight

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Effects of mechanical forces on signal transduction and gene expression in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Persistent S-nitrosation of complex I and other mitochondrial membrane proteins by S-nitrosothiols but not nitric oxide or peroxynitrite: implications for the interaction of nitric oxide with mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Vascular protection: superoxide dismutase isoforms in the vessel wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Respiratory uncoupling by UCP1 and UCP2 and superoxide generation in endothelial cell mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Radical medicine: treating ageing to cure disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mechanotransduction through the endothelial cytoskeleton: mediation of flow- but not agonist-induced EDRF release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Intrinsic and extrinsic uncoupling of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Effects of recombinant adenovirus-mediated uncoupling protein 2 overexpression on endothelial function and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial Complex I: structural and functional aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

The discovery of nitric oxide and its role in vascular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

ATVB in focus: redox mechanisms in blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

The role of reactive oxygen species in TNFalpha-dependent expression of the receptor for advanced glycation end products in human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Complex III releases superoxide to both sides of the inner mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Architecture of the Qo site of the cytochrome bc1 complex probed by superoxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Role for mitochondrial oxidants as regulators of cellular metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

An NADPH oxidase superoxide-generating system in the rabbit aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondria as signaling organelles in the vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondria, oxygen free radicals, disease and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Selective vulnerability of dopaminergic neurons to microtubule depolymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Reactive oxygen species production by mitochondria in endothelial cells exposed to reoxygenation after hypoxia and glucose depletion is mediated by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Hypoxic pulmonary vasoconstriction: redox events in oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Acute oxygen-sensing mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

Effect of cytochrome c on the generation and elimination of O2*- and H2O2 in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01283.2006

10.1152/AJPHEART.01283.2006

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17237240