(Q36732296)

English

Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis

scientific article published on July 2004

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scholarly article

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29 December 2019

Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis (English)

1 reference

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29 December 2019

1

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29 December 2019

author name string

Alex Vassilev

2

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29 December 2019

Melvin L DePamphilis

3

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29 December 2019

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publication date

1 July 2004

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29 December 2019

Molecular and Cellular Biology

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29 December 2019

24

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29 December 2019

5875-5886

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29 December 2019

13

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Europe PubMed Central

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29 December 2019

Localization of proteins bound to a replication origin of human DNA along the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Xenopus origin recognition complex (ORC) initiates DNA replication preferentially at sequences targeted by Schizosaccharomyces pombe ORC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

A p53-dependent checkpoint pathway prevents rereplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Active cyclin B1-Cdk1 first appears on centrosomes in prophase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Pharmacological inhibitors of cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Distinct roles for cyclins E and A during DNA replication complex assembly and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

DNA replication in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The origin recognition complex: from simple origins to complex functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Nuclear organization of DNA replication initiation proteins in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Control of DNA rereplication via Cdc2 phosphorylation sites in the origin recognition complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Architecture of the human origin recognition complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Assembly of the human origin recognition complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The human origin recognition complex protein 1 dissociates from chromatin during S phase in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Subsets of human origin recognition complex (ORC) subunits are expressed in non-proliferating cells and associate with non-ORC proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

A detailed analysis of cyclin A accumulation at the G(1)/S border in normal and transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Initiation of eukaryotic DNA replication: conservative or liberal?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Start sites of bidirectional DNA synthesis at the human lamin B2 origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Association of human origin recognition complex 1 with chromatin DNA and nuclease-resistant nuclear structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Temporal and spatial control of cyclin B1 destruction in metaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Simian virus 40 large T antigen associates with cyclin A and p33cdk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Eukaryotic DNA replication: anatomy of an origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Site-specific initiation of DNA replication in Xenopus egg extract requires nuclear structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Cyclin A is required at two points in the human cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

30 September 2017

Identification of a novel 81-kDa component of the Xenopus origin recognition complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

28 June 2018

Cell cycle modulation of protein-DNA interactions at a human replication origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

28 June 2018

The localization of p34cdc2 in the cells of normal, hyperplastic, and malignant epithelial and lymphoid tissues of the oral cavity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

28 June 2018

Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

5 September 2018

The binding of ORC2 to chromatin from terminally differentiated cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

5 September 2018

Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

5 September 2018

Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

5 September 2018

Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480893

5 September 2018

Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of re-replication control by overexpression of human ORC1 in fission yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A distinct G1 step required to specify the Chinese hamster DHFR replication origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of mammalian origin specification in ORC-depleted Xenopus egg extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein Kinase A is required for chromosomal DNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.24.13.5875-5886.2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15199143%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15199143%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15199143%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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