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28 February 2020

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21 February 2023

Genetics of obesity and type 2 diabetes in African Americans (English)

1 reference

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28 February 2020

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PubMed publication ID

2

1 reference

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28 February 2020

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Shana McCormack

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28 February 2020

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19 March 2013

9 references

13 March 2019

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28 February 2020

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21 February 2023

9 references

13 March 2019

14 March 2019

19 March 2019

24 March 2019

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2013

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28 February 2020

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396416

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases

30 September 2017

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Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium

30 September 2017

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The use of race, ethnicity and ancestry in human genetic research

30 September 2017

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Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans

30 September 2017

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30 September 2017

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A genome-wide association search for type 2 diabetes genes in African Americans

30 September 2017

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30 September 2017

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A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations

30 September 2017

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30 September 2017

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Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study

30 September 2017

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30 September 2017

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30 September 2017

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Body fat is differentially related to body mass index in U.S.-born African-American and East African immigrant girls

30 September 2017

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Does genetic ancestry explain higher values of glycated hemoglobin in African Americans?

30 September 2017

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Implication of European-derived adiposity loci in African Americans

30 September 2017

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30 September 2017

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An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference

30 September 2017

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30 September 2017

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Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort

30 September 2017

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Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant

30 September 2017

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Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups

30 September 2017

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Association of trypanolytic ApoL1 variants with kidney disease in African Americans

30 September 2017

1 reference

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Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study

30 September 2017

1 reference

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Fine mapping of the association with obesity at the FTO locus in African-derived populations

30 September 2017

1 reference

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Genome-wide association of anthropometric traits in African- and African-derived populations

30 September 2017

1 reference

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Genome-wide association studies in diverse populations

30 September 2017

1 reference

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FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

FTO genetic variation and association with obesity in West Africans and African Americans

30 September 2017

1 reference

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Population description and its role in the interpretation of genetic association

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Methodological challenges of genome-wide association analysis in Africa

30 September 2017

1 reference

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Common variants near melanocortin 4 receptor are associated with general and visceral adiposity in European- and African-American youth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Large, rare chromosomal deletions associated with severe early-onset obesity

30 September 2017

1 reference

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Life course variations in the associations between FTO and MC4R gene variants and body size

30 September 2017

1 reference

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30 September 2017

1 reference

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Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

The genetic structure and history of Africans and African Americans

30 September 2017

1 reference

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Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Population admixture associated with disease prevalence in the Boston Puerto Rican health study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

An obesity-associated FTO gene variant and increased energy intake in children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Genome-wide association studies: implications for multiethnic samples

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Common variants near MC4R are associated with fat mass, weight and risk of obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Principal components analysis corrects for stratification in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

The use of racial, ethnic, and ancestral categories in human genetics research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Beyond race: towards a whole-genome perspective on human populations and genetic variation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Implications of biogeography of human populations for 'race' and medicine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

The effects of human population structure on large genetic association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Bcl11a is essential for normal lymphoid development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

30 September 2017

Beyond body mass index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Race and health: basic questions, emerging directions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Positional cloning of the mouse obese gene and its human homologue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Comment on: Maruthur et al. Does genetic ancestry explain higher values of glycated hemoglobin in African Americans? Diabetes 2011;60:2434-2438.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Transethnic meta-analysis of genomewide association studies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Pitfalls in the use of HbA1c as a diagnostic test: the ethnic conundrum

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614120

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2013%2F396416

Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2013%2F396416

Health policy: endocrine health for all-finding and eliminating health disparities in endocrine disorders

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23577239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Body mass index and percent body fat: a meta analysis among different ethnic groups

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23577239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Association ofFTOGene Variants With Adiposity in African-American Adolescents

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23577239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2013/396416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577239%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577239%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

23577239

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577239%20AND%20SRC:MED&resulttype=core&format=json