(Q36746333)

16 August 2017

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title

The regulatory role of TGF-beta in airway remodeling in asthma (English)

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16 August 2017

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Toluwalope Makinde

1

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16 August 2017

Richard F Murphy

series ordinal

2

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16 August 2017

Devendra K Agrawal

series ordinal

3

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16 August 2017

publication date

27 February 2007

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Immunology & Cell Biology

16 August 2017

published in

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16 August 2017

volume

85

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16 August 2017

issue

5

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16 August 2017

page(s)

348-356

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Provocation with adenosine 5'-monophosphate increases sputum eosinophils

16 August 2017

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Angiogenesis and remodeling of airway vasculature in chronic inflammation

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Airway smooth muscle: immunomodulatory cells that modulate airway remodeling?

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Human bronchial fibroblasts express the 5-lipoxygenase pathway

21 January 2018

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Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

21 January 2018

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Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis.

21 January 2018

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A role for eosinophils in airway remodelling in asthma

21 January 2018

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Following the TRAIL to apoptosis

21 January 2018

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Transforming growth factor-beta and its role in asthma

21 January 2018

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Regional fibroblast heterogeneity in the lung: implications for remodeling

21 January 2018

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Connective tissue growth factor and vascular endothelial growth factor from airway smooth muscle interact with the extracellular matrix

21 January 2018

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Lung mucus: a clinician's view

21 January 2018

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Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma

21 January 2018

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Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways

21 January 2018

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Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids.

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Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma.

21 January 2018

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Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma?

21 January 2018

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Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling

21 January 2018

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The role of the mast cell in asthma: a reassessment

21 January 2018

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Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma

21 January 2018

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Cytoskeletal remodeling of the airway smooth muscle cell: a mechanism for adaptation to mechanical forces in the lung.

21 January 2018

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Molecular mechanisms of blood vessel formation

21 January 2018

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Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway

21 January 2018

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Regulation of biglycan gene expression by transforming growth factor-beta requires MKK6-p38 mitogen-activated protein Kinase signaling downstream of Smad signaling

21 January 2018

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Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma.

21 January 2018

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Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads

21 January 2018

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TGF-beta: from latent to active

21 January 2018

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Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK.

21 January 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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Structural and functional characterization of the transforming growth factor-beta -induced Smad3/c-Jun transcriptional cooperativity.

21 January 2018

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Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts

21 January 2018

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

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Smad and p38-MAPK signaling mediates apoptotic effects of transforming growth factor-beta1 in human airway epithelial cells

21 January 2018

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Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

21 January 2018

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C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts

21 January 2018

1 reference

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Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta

21 January 2018

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Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase

21 January 2018

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Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells

21 January 2018

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Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Human umbilical vein endothelial cells generate leukotriene C4 via microsomal glutathione S-transferase type 2 and express the CysLT(1) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Differential proliferation of fibroblasts cultured from normal and fibrotic human lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Epithelial expression of profibrotic mediators in a model of allergen-induced airway remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

TGF-beta1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

In vitro wounding of airway smooth muscle cell monolayers increases expression of TGF-beta receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Release of biologically active TGF-beta from airway smooth muscle cells induces autocrine synthesis of collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Airway smooth muscle—its relationship to the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Vascular endothelial growth factor modulates matrix metalloproteinase-9 expression in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Smad3 mediates TGF-beta1 induction of VEGF production in lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Integrins in pulmonary inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

beta1-Integrins mediate enhancement of airway smooth muscle proliferation by collagen and fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Transforming growth factor-beta1 stimulates vascular endothelial growth factor 164 via mitogen-activated protein kinase kinase 3-p38alpha and p38delta mitogen-activated protein kinase-dependent pathway in murine mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Transforming growth factor-beta stimulates vascular endothelial growth factor production by folliculostellate pituitary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

The expression of transforming growth factor-beta1 is significantly correlated with the expression of vascular endothelial growth factor and poor prognosis of patients with advanced gastric carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

TH2 Cytokine-enhanced and TGF-beta-enhanced vascular endothelial growth factor production by cultured human airway smooth muscle cells is attenuated by IFN-gamma and corticosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Differential regulation of VEGF by TGF-beta and hypoxia in rat proximal tubular cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Anti-fibrotic effects of theophylline on lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

Airway remodeling in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Human airway narrowing measured using high resolution computed tomography

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7 January 2021

[Airway remodeling in asthma: mechanisms and therapeutic perspectives]

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7 January 2021

The mechanics of airway narrowing in asthma

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Enhanced proteoglycan deposition in the airway wall of atopic asthmatics

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Myofibroblasts and subepithelial fibrosis in bronchial asthma

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7 January 2021

Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis

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7 January 2021

Inhaled corticosteroids decrease subepithelial collagen deposition by modulation of the balance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 expression in asthma

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7 January 2021

Bronchial elastic fibers in normal subjects and asthmatic patients

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7 January 2021

The airway longitudinal elastic fiber network and mucosal folding in patients with asthma

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Elastosis and fragmentation of fibers of the elastic system in fatal asthma

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7 January 2021

Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100044

7 January 2021

GM-CSF increases airway smooth muscle cell connective tissue expression by inducing TGF-beta receptors

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7 January 2021

Manipulation of allergen-induced airway remodeling by treatment with anti-TGF-beta antibody: effect on the Smad signaling pathway

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7 January 2021

Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts

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7 January 2021

Smad7 inhibits the survival nuclear factor kappaB and potentiates apoptosis in epithelial cells

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7 January 2021

Transforming growth Factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinase-dependent pathway

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7 January 2021

Regulation of TGF-β1-induced connective tissue growth factor expression in airway smooth muscle cells

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7 January 2021

Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)

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7 January 2021

TGF-beta1 stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells

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7 January 2021

Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle

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7 January 2021

Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells

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7 January 2021

Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase

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7 January 2021

Hypoxia augments cytokine (transforming growth factor-beta (TGF-beta) and IL-1)-induced vascular endothelial growth factor secretion by human synovial fibroblasts

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7 January 2021

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

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7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100044

1 reference

Dimensions Publication ID

16 August 2017

1018118290

0 references

1 reference