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HIV reservoirs and latency models.
scientific article published on February 2011
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Europe PubMed Central
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3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
review article
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Europe PubMed Central
title
HIV reservoirs and latency models
(English)
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Europe PubMed Central
PMC publication ID
3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
author
Matthew J Pace
series ordinal
1
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Europe PubMed Central
PMC publication ID
3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
author name string
Luis Agosto
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2
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Europe PubMed Central
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3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
Erin H Graf
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3
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Europe PubMed Central
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3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
Una O'Doherty
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4
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3618966
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21 January 2020
language of work or name
English
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publication date
1 February 2011
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Europe PubMed Central
PMC publication ID
3618966
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retrieved
21 January 2020
published in
Virology
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Europe PubMed Central
PMC publication ID
3618966
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
volume
411
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Europe PubMed Central
PMC publication ID
3618966
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
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21 January 2020
issue
2
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Europe PubMed Central
PMC publication ID
3618966
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21 January 2020
page(s)
344-354
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Europe PubMed Central
PMC publication ID
3618966
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21 January 2020
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Humanized Rag2(-/-)gammac(-/-) (RAG-hu) mice can sustain long-term chronic HIV-1 infection lasting more than a year
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The CXCR4-tropic human immunodeficiency virus envelope promotes more-efficient gene delivery to resting CD4+ T cells than the vesicular stomatitis virus glycoprotein G envelope
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The level of monocyte turnover predicts disease progression in the macaque model of AIDS.
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Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation
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In vivo analysis of dendritic cell development and homeostasis
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The challenge of finding a cure for HIV infection
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Human immunodeficiency virus integrates directly into naive resting CD4+ T cells but enters naive cells less efficiently than memory cells
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Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR.
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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control
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29 September 2017
Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy
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HIV rebounds from latently infected cells, rather than from continuing low-level replication
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Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells
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Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.
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HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells
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Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
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29 September 2017
Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein
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29 September 2017
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
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HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration.
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Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells
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Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells
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29 September 2017
Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells
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R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells
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29 September 2017
Rapid expression of human immunodeficiency virus following activation of latently infected cells
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29 September 2017
Retroviral infection of non-dividing cells: old and new perspectives
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29 September 2017
HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir
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29 September 2017
Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli
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29 September 2017
Perils at mucosal front lines for HIV and SIV and their hosts
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29 September 2017
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
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29 September 2017
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29 September 2017
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29 September 2017
IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.
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29 September 2017
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29 September 2017
Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo
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29 September 2017
Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection
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29 September 2017
T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis
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29 September 2017
Peripheral blood Dendritic cells are not a major reservoir for HIV type 1 in infected individuals on virally suppressive HAART.
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29 September 2017
Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
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29 September 2017
Identification of T cell-signaling pathways that stimulate latent HIV in primary cells
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29 September 2017
CD154-CD40-induced reactivation of latent HIV-1 infection
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29 September 2017
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29 September 2017
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29 September 2017
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.
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29 September 2017
Resting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy
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29 September 2017
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype
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29 September 2017
Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus
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29 September 2017
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29 September 2017
Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy
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29 September 2017
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells
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29 September 2017
Human immunodeficiency virus type-1 and chemokines: beyond competition for common cellular receptors
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29 September 2017
Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans
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29 September 2017
Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection
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29 September 2017
Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
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29 September 2017
Exploitation of cellular signaling by HIV-1: unwelcome guests with master keys that signal their entry
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29 September 2017
Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy
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29 September 2017
Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1.
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29 September 2017
Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy
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29 September 2017
In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline
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29 September 2017
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
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29 September 2017
Immuno-activation with anti-CD3 and recombinant human IL-2 in HIV-1-infected patients on potent antiretroviral therapy
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29 September 2017
Both memory and CD45RA+/CD62L+ naive CD4(+) T cells are infected in human immunodeficiency virus type 1-infected individuals
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29 September 2017
Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
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29 September 2017
Constant mean viral copy number per infected cell in tissues regardless of high, low, or undetectable plasma HIV RNA.
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29 September 2017
Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
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29 September 2017
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
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29 September 2017
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
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29 September 2017
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
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29 September 2017
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
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29 September 2017
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team
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29 September 2017
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
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29 September 2017
Accumulation of defective viral genomes in peripheral blood mononuclear cells of human immunodeficiency virus type 1-infected individuals.
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29 September 2017
Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds
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29 September 2017
Human hematolymphoid cells in SCID mice
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29 September 2017
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
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29 September 2017
In vivo estimates of division and death rates of human T lymphocytes
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29 September 2017
Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro
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29 September 2017
Infection frequency of dendritic cells and CD4+ T lymphocytes in spleens of human immunodeficiency virus-positive patients
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29 September 2017
Viral dynamics in human immunodeficiency virus type 1 infection
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29 September 2017
HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure
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29 September 2017
HIV-1 replication is controlled at the level of T cell activation and proviral integration
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29 September 2017
Analysis of human immunodeficiency virus type 1 viremia and provirus in resting CD4+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy
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28 June 2018
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28 June 2018
Novel pathway for induction of latent virus from resting CD4(+) T cells in the simian immunodeficiency virus/macaque model of human immunodeficiency virus type 1 latency.
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28 June 2018
Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors.
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28 June 2018
High-resolution structure of an HIV-1 quasispecies: identification of novel coding sequences
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28 June 2018
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28 June 2018
R5 HIV env and vesicular stomatitis virus G protein cooperate to mediate fusion to naive CD4+ T Cells.
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5 September 2018
Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy
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5 September 2018
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5 September 2018
An in vitro system to model the establishment and reactivation of HIV-1 latency.
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5 September 2018
Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro
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5 September 2018
Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells
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5 September 2018
CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency.
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5 September 2018
CD16+ monocyte subset preferentially harbors HIV-1 and is expanded in pregnant Malawian women with Plasmodium falciparum malaria and HIV-1 infection
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5 September 2018
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5 September 2018
A novel in vitro system to generate and study latently HIV-infected long-lived normal CD4+ T-lymphocytes.
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5 September 2018
The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells
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5 September 2018
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5 September 2018
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5 September 2018
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5 September 2018
HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
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5 September 2018
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5 September 2018
Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infection.
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IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes
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5 September 2018
HIV-1 actively replicates in naive CD4(+) T cells residing within human lymphoid tissues
1 reference
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PubMed Central
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5 September 2018
Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load
1 reference
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PubMed Central
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5 September 2018
OKT3 and IL-2 treatment for purging of the latent HIV-1 reservoir in vivo results in selective long-lasting CD4+ T cell depletion.
1 reference
stated in
PubMed Central
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5 September 2018
Generation of HIV latency during thymopoiesis
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PubMed Central
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5 September 2018
Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy.
1 reference
stated in
PubMed Central
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5 September 2018
Human immunodeficiency virus type 1 quasi species that rebound after discontinuation of highly active antiretroviral therapy are similar to the viral quasi species present before initiation of therapy
1 reference
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PubMed Central
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5 September 2018
Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy.
1 reference
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5 September 2018
Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy.
1 reference
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5 September 2018
Rapid accumulation of human immunodeficiency virus (HIV) in lymphatic tissue reservoirs during acute and early HIV infection: implications for timing of antiretroviral therapy
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5 September 2018
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
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PubMed Central
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5 September 2018
Binding of HIV-1 virions or gp120-anti-gp120 immune complexes to HIV-1-infected quiescent peripheral blood mononuclear cells reveals latent infection
1 reference
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PubMed Central
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5 September 2018
In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency.
1 reference
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5 September 2018
Immune control of HIV-1 after early treatment of acute infection
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PubMed Central
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4 December 2018
Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs
1 reference
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https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
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7 January 2021
The CD16+ Monocyte Subset Is More Permissive to Infection and Preferentially Harbors HIV-1 In Vivo
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
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7 January 2021
Correction: Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
retrieved
7 January 2021
Productive HIV Infection of Resting CD4+T Cells: Role of Lymphoid Tissue Microenvironment and Effect of Immunomodulating Agents
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
retrieved
7 January 2021
Host factors regulating post-integration latency of HIV
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
retrieved
7 January 2021
A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
retrieved
7 January 2021
Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.12.041
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7 January 2021
Observations on human monocyte kinetics after pulse labeling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21284992
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.VIROL.2010.12.041
1 reference
stated in
Europe PubMed Central
PMC publication ID
3618966
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PMC publication ID
3618966
1 reference
stated in
Europe PubMed Central
PMC publication ID
3618966
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PubMed publication ID
21284992
1 reference
stated in
Europe PubMed Central
PMC publication ID
3618966
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284992%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
ResearchGate publication ID
49801914
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