(Q36747874)

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Catalytic mechanism of cytochrome P450 for N-methylhydroxylation of nicotine: reaction pathways and regioselectivity of the enzymatic nicotine oxidation

scientific article published on 9 January 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Catalytic mechanism of cytochrome P450 for N-methylhydroxylation of nicotine: reaction pathways and regioselectivity of the enzymatic nicotine oxidation (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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Dongmei Li

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Xiaoqin Huang

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Jianping Lin

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Chang-Guo Zhan

4

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Europe PubMed Central

PMC publication ID

16 August 2017

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publication date

9 January 2013

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Europe PubMed Central

PMC publication ID

16 August 2017

Dalton Transactions

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Europe PubMed Central

PMC publication ID

16 August 2017

42

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Europe PubMed Central

PMC publication ID

16 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

3812-3820

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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1 reference

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Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity

1 reference

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Aspects of the oxidative metabolism of nicotine

1 reference

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Metabolism of nicotine

1 reference

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The enzyme “aldehyde oxidase” is an iminium oxidase. Reaction with nicotine Δ1′(5′) iminium ion

1 reference

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Reaction pathway and free energy profiles for butyrylcholinesterase-catalyzed hydrolysis of acetylthiocholine.

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Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity.

1 reference

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Reaction mechanism for cocaine esterase-catalyzed hydrolyses of (+)- and (-)-cocaine: unexpected common rate-determining step

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Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine.

1 reference

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Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems

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Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide

1 reference

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Reaction pathway and free energy profile for butyrylcholinesterase-catalyzed hydrolysis of acetylcholine

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1 reference

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1 reference

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1 reference

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1 reference

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Improved pseudobonds for combined ab initio quantum mechanical/molecular mechanical methods

1 reference

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Stereoselectivity and isotope effects associated with cytochrome P450-catalyzed oxidation of (S)-nicotine. The possibility of initial hydrogen atom abstraction in the formation of the delta 1', 5-nicotinium ion

1 reference

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Identifiers

10.1039/C2DT32106H

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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