(Q36752669)

16 August 2017

The antibody catalysis route to the total synthesis of epothilones (English)

1 reference

16 August 2017

Sinha SC

1

1 reference

16 August 2017

Barbas CF 3rd

series ordinal

2

1 reference

16 August 2017

Lerner RA

series ordinal

3

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 December 1998

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

95

1 reference

16 August 2017

25

1 reference

16 August 2017

14603-14608

1 reference

Epothilone A induces apoptosis in neuroblastoma cells with multiple mechanisms of drug resistance

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Epothilone B stabilizes microtubuli of macrophages like taxol without showing taxol-like endotoxin activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Synthesis of epothilones A and B in solid and solution phase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Antibody-catalyzed reversal of chemoselectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Selective chemical catalysis by an antibody

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Controlling chemical reactivity with antibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Synthesis and biological properties of C12,13-cyclopropyl-epothilone A and related epothilones

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Total Syntheses of Epothilones A and B via a Macrolactonization-Based Strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Total Synthesis of(–)-Epothilone A

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Directed evolution of an esterase for the stereoselective resolution of a key intermediate in the synthesis of epothilones

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24496

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

20 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

21 January 2018

Reactive immunization

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Chemical Biology of Epothilones

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Total Synthesis of Epothilone A: The Olefin Metathesis Approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Total Synthesis of(−)-Epothilone A

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Studies toward a Synthesis of Epothilone A: Use of Hydropyran Templates for the Management of Acyclic Stereochemical Relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Studies toward a Synthesis of Epothilone A: Stereocontrolled Assembly of the Acyl Region and Models for Macrocyclization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution of β-Hydroxyketones with Aldolase Antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14603

Asymmetric organic synthesis with catalytic antibodies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9843936

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.95.25.14603

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

9843936

1 reference