(Q36761184)

16 August 2017

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title

A fatty-acid synthesis mechanism specialized for parasitism (English)

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16 August 2017

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author name string

Soo Hee Lee

series ordinal

1

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16 August 2017

Jennifer L Stephens

series ordinal

2

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16 August 2017

Paul T Englund

series ordinal

3

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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Nature Reviews Microbiology

16 August 2017

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16 August 2017

5

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4

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16 August 2017

287-297

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https://scigraph.springernature.com/pub.10.1038/nrmicro1617

16 August 2017

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cites work

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Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery.

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Adaptations in the lipid metabolism of the protozoan parasite Trypanosoma brucei

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African trypanosome interactions with an in vitro model of the human blood-brain barrier

31 March 2020

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Energy generation in insect stages of Trypanosoma brucei: metabolism in flux

31 March 2020

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The lipid metabolism of blood and culture forms of Trypanosoma lewisi and Trypanosoma rhodesiense

31 March 2020

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The acquisition of lipids by African trypanosomes

31 March 2020

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Fatty acid uptake by bloodstream forms of Trypanosoma brucei and other species of the kinetoplastida

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1617

The lipid composition of blood and culture forms of Trypanosoma lewisi and Trypanosoma rhodesiense compared with that of their environment

31 March 2020

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Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite

31 March 2020

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Receptor-mediated endocytosis in the bloodstream form of Trypanosoma brucei

31 March 2020

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Evidence for a Trypanosoma brucei lipoprotein scavenger receptor

31 March 2020

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Host plasma low density lipoprotein particles as an essential source of lipids for the bloodstream forms of Trypanosoma brucei

31 March 2020

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The role of threonine in the metabolism of acetyl coenzyme a by Trypanosoma brucei brucei

31 March 2020

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Antigenic variation and the African trypanosome genome

31 March 2020

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Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

31 March 2020

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Utilization of amino acids byTrypanosoma bruceiin culture: L-threonine as a precursor for acetate

31 March 2020

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The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

31 March 2020

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Forty years of bacterial fatty acid synthesis

31 March 2020

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Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae

31 March 2020

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Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae

31 March 2020

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ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation

31 March 2020

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The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase

31 March 2020

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Fatty acid elongases in mammals: their regulation and roles in metabolism

31 March 2020

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Elongation of long-chain fatty acids

31 March 2020

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Cloning and functional characterisation of an enzyme involved in the elongation of Delta6-polyunsaturated fatty acids from the moss Physcomitrella patens

31 March 2020

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Members of the Arabidopsis FAE1-like 3-ketoacyl-CoA synthase gene family substitute for the Elop proteins of Saccharomyces cerevisiae

31 March 2020

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Cultivation of Leishmania donovani and Leishmania braziliensis in defined media: nutritional requirements

31 March 2020

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Trypanosoma brucei oleate desaturase may use a cytochrome b5-like domain in another desaturase as an electron donor

31 March 2020

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Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan

31 March 2020

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Molecular species analysis of phospholipids from Trypanosoma brucei bloodstream and procyclic forms

31 March 2020

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Lipid composition of Trypanosoma cruzi

31 March 2020

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Lipid content of the slender and stumpy forms of Trypanosoma brucei rhodesiense: A comparative study

31 March 2020

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The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols

31 March 2020

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The surface glycoconjugates of trypanosomatid parasites.

31 March 2020

1 reference

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Localization of the initial steps in alkoxyphospholipid biosynthesis in glycosomes (microbodies) of Trypanosoma brucei

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1617

In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1617

Alkyl dihydroxyacetone phosphate synthase in glycosomes of Trypanosoma brucei.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

The dihydroxyacetonephosphate pathway for biosynthesis of ether lipids in Leishmania mexicana promastigotes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1617

MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Temperature acclimation of Trypanosoma cruzi epimastigote and metacyclic trypomastigote lipids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Lipid metabolism in mucous-dwelling amitochondriate protozoa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Fatty acid and sterol metabolism of cultured Trichomonas vaginalis and Tritrichomonas foetus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

'FAS't inhibition of malaria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

The human malaria parasite Plasmodium falciparum has distinct organelle-specific lipoylation pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

What is the phylogenetic position of Cryptosporidium?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Current progress in the fatty acid metabolism in Cryptosporidium parvum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Molecular analysis of a Type I fatty acid synthase in Cryptosporidium parvum.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Mitochondrial acyl carrier protein is involved in lipoic acid synthesis in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Why do mitochondria synthesize fatty acids? Evidence for involvement in lipoic acid production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Carbon flux and fatty acid synthesis in plants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Fatty acid and lipoic acid biosynthesis in higher plant mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

The characterization of a mitochondrial acyl carrier protein isoform isolated from Arabidopsis thaliana

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

De novo fatty acid synthesis mediated by acyl-carrier protein in Neurospora crassa mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Multiple triclosan targets in Trypanosoma brucei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

The evolution and diversity of kinetoplastid flagellates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

More plastids in human parasites?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Comparative genomics of trypanosomatid parasitic protozoa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

A kingdom-level phylogeny of eukaryotes based on combined protein data

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Early catalytic steps of Euglena gracilis chloroplast type II fatty acid synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Did trypanosomatid parasites have photosynthetic ancestors?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Effects of a first exposure to ethanol on the compositions of neutral and polar lipids in Euglena gracilis Z, taken as a hepatic cell model: equilibration by citrulline-malate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Mechanism of action of the antibiotic thiolactomycin inhibition of fatty acid synthesis of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Triclosan targets lipid synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

A diazaborine derivative inhibits lipopolysaccharide biosynthesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Analogues of thiolactomycin as potential antimalarial agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Discovery of bacterial fatty acid synthase inhibitors from a Phoma species as antimicrobial agents using a new antisense-based strategy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Carnitine stimulates ATP synthesis in Trypanosoma brucei brucei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

Carnitine in Trypanosoma brucei brucei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

The trypanolytic factor of human serum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1617

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1617

1 reference

16 August 2017

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