(Q36764007)

16 August 2017

1 reference

title

N-cadherin as a therapeutic target in cancer (English)

1 reference

16 August 2017

Agnese Mariotti

1

1 reference

16 August 2017

Antonella Perotti

series ordinal

2

1 reference

16 August 2017

Cristiana Sessa

series ordinal

3

1 reference

16 August 2017

Curzio Rüegg

series ordinal

4

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 April 2007

1 reference

Expert Opinion on Investigational Drugs

16 August 2017

published in

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16 August 2017

volume

16

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16 August 2017

issue

4

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16 August 2017

page(s)

451-465

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Regulation of cadherin-mediated adhesion in morphogenesis

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

A monoclonal antibody disrupting calcium-dependent cell-cell adhesion of brain tissues: possible role of its target antigen in animal pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Enzymatic dissection of embryonic cell adhesive mechanisms. II. Developmental regulation of an endogenous adhesive system in the chick neural retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Functional cis-heterodimers of N- and R-cadherins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Structural basis of cell-cell adhesion by cadherins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Structure-function analysis of cell adhesion by neural (N-) cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

In the first extracellular domain of E-cadherin, heterophilic interactions, but not the conserved His-Ala-Val motif, are required for adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

INP, a novel N-cadherin antagonist targeted to the amino acids that flank the HAV motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Multiple cadherin extracellular repeats mediate homophilic binding and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Developmental defects in mouse embryos lacking N-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Molecular modification of N-cadherin in response to synaptic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cadherins: molecular codes for axon guidance and synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Role of N-cadherin in bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin promotes the commitment and differentiation of skeletal muscle precursor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin-catenin interaction: necessary component of cardiac cell compartmentalization during early vertebrate heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Trabecular myocytes of the embryonic heart require N-cadherin for migratory unit identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-Cadherin, a cell adhesion molecule involved in establishment of embryonic left-right asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin is required for neural crest remodeling of the cardiac outflow tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Integrins: regulators of tissue function and cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cadherin switch in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin expression in adrenal tumors: upregulation in malignant pheochromocytoma and downregulation in adrenocortical carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin-mediated cell contact regulates ovarian surface epithelial cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cortactin associates with N-cadherin adhesions and mediates intercellular adhesion strengthening in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Cross talk between adhesion molecules: control of N-cadherin activity by intracellular signals elicited by beta1 and beta3 integrins in migrating neural crest cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

The nonreceptor tyrosine kinase fer mediates cross-talk between N-cadherin and beta1-integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

PTP1B modulates the association of beta-catenin with N-cadherin through binding to an adjacent and partially overlapping target site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Rho-family GTPases in cadherin-mediated cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Coordinate regulation of cadherin and integrin function by the chondroitin sulfate proteoglycan neurocan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Induction of apoptosis in cultured endothelial cells by a cadherin antagonist peptide: involvement of fibroblast growth factor receptor-mediated signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Structural basis for FGF receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Two regions of cadherin cytoplasmic domains are involved in suppressing motility of a mammary carcinoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Purification and characterization of NCAD90, a soluble endogenous form of N-cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Structure and function of sphingolipid- and cholesterol-rich membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Lipid rafts and membrane dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Migration of nerve growth cones requires detergent-resistant membranes in a spatially defined and substrate-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin association with lipid rafts regulates its dynamic assembly at cell-cell junctions in C2C12 myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Endothelial cadherins and tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin expression in endothelial cells during early angiogenesis in the eye and brain of the chicken: relation to blood-retina and blood-brain barrier development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin mediates pericytic-endothelial interaction during brain angiogenesis in the chicken

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Soluble N-cadherin fragment promotes angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

N-cadherin mediates endocytosis of Candida albicans by endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Single-molecule analysis of cadherin-mediated cell-cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Vascular integrins in tumor angiogenesis: mediators and therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

Expression of cadherins and catenins correlates with distinct histologic types of ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.4.451

10.1517/13543784.16.4.451

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference