(Q36764667)

English

H-ras mutants lacking the epitope for the neutralizing monoclonal antibody Y13-259 show decreased biological activity and are deficient in GTPase-activating protein interaction

scientific article published on April 1989

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

H-ras mutants lacking the epitope for the neutralizing monoclonal antibody Y13-259 show decreased biological activity and are deficient in GTPase-activating protein interaction (English)

1 reference

Europe PubMed Central

16 August 2017

monoclonal antibody

1 reference

based on heuristic

inferred from title

author name string

Srivastava SK

1

1 reference

Europe PubMed Central

16 August 2017

Di Donato A

2

1 reference

Europe PubMed Central

16 August 2017

Lacal JC

3

1 reference

Europe PubMed Central

16 August 2017

language of work or name

0 references

publication date

1 April 1989

1 reference

Europe PubMed Central

16 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

16 August 2017

9

1 reference

Europe PubMed Central

16 August 2017

1779-1783

1 reference

Europe PubMed Central

16 August 2017

4

1 reference

Europe PubMed Central

16 August 2017

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Analysis of the transforming potential of the human H-ras gene by random mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.

1 reference

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29 September 2017

Mechanism of activation of a human oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins

1 reference

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29 September 2017

A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

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29 September 2017

Effects of two major activating lesions on the structure and conformation of human ras oncogene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 reference

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29 September 2017

Biochemical and biological properties of the human N-ras p21 protein

1 reference

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29 September 2017

Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Mutational analysis of a ras catalytic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Deletion mutants of Harvey ras p21 protein reveal the absolute requirement of at least two distant regions for GTP-binding and transforming activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Monoclonal antibody Y13-259 recognizes an epitope of the p21 ras molecule not directly involved in the GTP-binding activity of the protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

29 September 2017

Comparative biochemical properties of normal and activated human ras p21 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

The p21 ras C-terminus is required for transformation and membrane association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

Biological and biochemical properties of human rasH genes mutated at codon 61.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

Requirement for c-ras proteins during viral oncogene transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

28 June 2018

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362597

5 September 2018

32 Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2471068

12 December 2020

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inferred from PubMed ID database lookup

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10.1128/MCB.9.4.1779

1 reference

Europe PubMed Central

16 August 2017

release_g6u5br5h5vhqdjmcqvmf5mabmi

1 reference

https://api.fatcat.wiki/v0/release/g6u5br5h5vhqdjmcqvmf5mabmi

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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