(Q36769062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Therapeutic potential of targeting the renin angiotensin system in portal hypertension (English)

1 reference

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28 February 2020

1

1 reference

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28 February 2020

author name string

Josephine A Grace

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Peter W Angus

series ordinal

3

1 reference

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28 February 2020

publication date

1 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

World journal of gastrointestinal pathophysiology

28 February 2020

published in

1 reference

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28 February 2020

volume

4

1 reference

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

1-11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney

28 February 2020

cites work

1 reference

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29 September 2017

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29 September 2017

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29 September 2017

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Vascular hyporesponsiveness to angiotensin II in rats with CCl(4)-induced liver cirrhosis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Impact of inhibitors of the Renin-Angiotensin-aldosterone system on liver fibrosis and portal hypertension

29 September 2017

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Role of endothelin in systemic and portal resistance in cirrhosis

29 September 2017

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Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-beta with a combination of imatinib mesylate and ACE inhibitor in rats.

29 September 2017

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Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis.

29 September 2017

1 reference

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Nitric oxide and portal hypertension: interface of vasoreactivity and angiogenesis

29 September 2017

1 reference

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Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.

29 September 2017

1 reference

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Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function

29 September 2017

1 reference

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Increased hepatic resistance: a new target in the pharmacologic therapy of portal hypertension.

29 September 2017

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29 September 2017

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Angiotensin-converting enzyme-2: a molecular and cellular perspective

29 September 2017

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Octreotide in hepatorenal syndrome: a randomized, double-blind, placebo-controlled, crossover study

29 September 2017

1 reference

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Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

29 September 2017

1 reference

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Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor

29 September 2017

1 reference

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Inflammation and angiotensin II.

29 September 2017

1 reference

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Terlipressin for acute esophageal variceal hemorrhage

29 September 2017

1 reference

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A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis.

29 September 2017

1 reference

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Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan

29 September 2017

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Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis.

29 September 2017

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The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough

29 September 2017

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Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase

29 September 2017

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Angiotensin II and renal fibrosis.

29 September 2017

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Cellular and molecular basis of portal hypertension

29 September 2017

1 reference

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Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleeding

29 September 2017

1 reference

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Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

29 September 2017

1 reference

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Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats

29 September 2017

1 reference

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Current management of the complications of cirrhosis and portal hypertension: variceal hemorrhage, ascites, and spontaneous bacterial peritonitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Nitric oxide and portal hypertension: its role in the regulation of intrahepatic and splanchnic vascular resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis

29 September 2017

1 reference

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Release of angiotensin-(1-7) from the rat hindlimb: influence of angiotensin-converting enzyme inhibition

29 September 2017

1 reference

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Hepatic and splanchnic nitric oxide activity in patients with cirrhosis

29 September 2017

1 reference

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Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells

29 September 2017

1 reference

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Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells

29 September 2017

1 reference

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Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

29 September 2017

1 reference

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The treatment of portal hypertension: A meta-analytic review

29 September 2017

1 reference

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Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis.

29 September 2017

1 reference

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Enhanced vascular responses to noradrenaline in isolated omental arteries from patients with advanced cirrhosis: evidence against intrinsic vascular hyporeactivity in cirrhosis.

29 September 2017

1 reference

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Hepatic tissue endothelin-1 levels in chronic liver disease correlate with disease severity and ascites

27 June 2018

1 reference

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Angiotensin 1-7 induces bradykinin-mediated relaxation in porcine coronary artery

27 June 2018

1 reference

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Second study shows that octreotide may prevent early rebleeding in cirrhosis

27 June 2018

1 reference

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Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor

27 June 2018

1 reference

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Reduced vascular sensitivity to norepinephrine in portal-hypertensive rats.

27 June 2018

1 reference

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Prevention of first bleeding in cirrhosis. A meta-analysis of randomized trials of nonsurgical treatment

27 June 2018

1 reference

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In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats

27 June 2018

1 reference

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Production of angiotensin-(1-7) by human vascular endothelium

27 June 2018

1 reference

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Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Aliskiren combined with losartan in type 2 diabetes and nephropathy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Vasoconstrictor responses are normal but prostanoid-mediated vasodilatation is enhanced in human cirrhotic mesenteric arteries

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Fate of bradykinin on the rat liver when administered by the venous or arterial route.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Impaired agonist-dependent myosin phosphorylation and decreased RhoA in rat portal hypertensive mesenteric vasculature.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Vascular hyporesponsiveness in the mesenteric artery of anaesthetized rats with cirrhosis and portal hypertension: an in-vivo study

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Anti-VEGF receptor-2 monoclonal antibody prevents portal-systemic collateral vessel formation in portal hypertensive mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Pregnancy enhances the angiotensin (Ang)-(1-7) vasodilator response in mesenteric arteries and increases the renal concentration and urinary excretion of Ang-(1-7).

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Portal hypertension is associated with increased mRNA levels of vasopressor G-protein-coupled receptors in human hepatic arteries

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Altered adrenergic responsiveness of endothelium-denuded hepatic arteries and portal veins in patients with cirrhosis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Peripheral vascular tone in patients with cirrhosis: role of the renin-angiotensin and sympathetic nervous systems

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Counterregulatory actions of angiotensin-(1-7).

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627462

Plasma noradrenaline in cirrhosis: a study of kinetics and temporal relationship to ascites formation

5 September 2018

1 reference

12 December 2020

Enhanced vasoconstrictor prostanoid production by sinusoidal endothelial cells increases portal perfusion pressure in cirrhotic rat livers

1 reference

12 December 2020

Vasoactive agents in intrahepatic portal hypertension and fibrogenesis: implications for therapy

1 reference

12 December 2020

Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats

1 reference

12 December 2020

Long-term outcome of patients treated with terlipressin for types 1 and 2 hepatorenal syndrome

1 reference

12 December 2020

Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis

1 reference

12 December 2020

Vascular dysfunction in human and rat cirrhosis: role of receptor-desensitizing and calcium-sensitizing proteins

1 reference

12 December 2020

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver

1 reference

12 December 2020

Portal vascular responsiveness to sympathetic stimulation and nitric oxide in cirrhotic rats

1 reference

12 December 2020

Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding

1 reference

12 December 2020

NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats

1 reference

12 December 2020

Nitric oxide synthase activity in the splanchnic vasculature of patients with cirrhosis: relationship with hemodynamic disturbances

1 reference

12 December 2020

Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis

1 reference

12 December 2020

Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver

1 reference

12 December 2020

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

1 reference

12 December 2020

New insights into the pathobiology of portal hypertension

1 reference

12 December 2020

Contractile hyporesponsiveness of hepatic arteries in humans with cirrhosis: evidence for a receptor-specific mechanism

1 reference

12 December 2020

Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats

1 reference

12 December 2020

Evidence for a new angiotensin-(1–7) receptor subtype in the aorta of Sprague–Dawley rats

1 reference

12 December 2020

Nitric oxide mediates the reduced vasoconstrictor response to angiotensin II in patients with preascitic cirrhosis

1 reference

12 December 2020

In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade

1 reference

12 December 2020

Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME

1 reference

12 December 2020

Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide

1 reference

12 December 2020

Vascular hyporesponsiveness to endothelin 1 in rats with cirrhosis

1 reference

12 December 2020

Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat

1 reference

12 December 2020

Identifiers

DOI

10.4291/WJGP.V4.I1.1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

23596549

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23596549%20AND%20SRC:MED&resulttype=core&format=json