(Q36777361)

16 August 2017

Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? (English)

1 reference

16 August 2017

Y Li

1

1 reference

16 August 2017

C Prives

series ordinal

2

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 April 2007

1 reference

16 August 2017

1 reference

16 August 2017

26

1 reference

16 August 2017

15

1 reference

16 August 2017

2220-2225

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210311

16 August 2017

0 references

cites work

Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

ASPP1 and ASPP2: common activators of p53 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

P63 gene mutations and human developmental syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Dissecting p53-dependent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

AIS is an oncogene amplified in squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Transcriptional regulation by p53: one protein, many possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p53 and p73 display common and distinct requirements for sequence specific binding to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Transcriptional regulation by p53 and p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p73 can suppress the proliferation of cells that express mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Strategies for therapeutic targeting of the p53 pathway in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

SSRP1 functions as a co-activator of the transcriptional activator p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Chemosensitivity linked to p73 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210311

1 reference

release_uqfbdippgja6rfelsswikpslny

16 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uqfbdippgja6rfelsswikpslny

24 November 2022

mapped directly with Wikidata item

1 reference