(Q36790259)

English

Preclinical Activity of Simvastatin Induces Cell Cycle Arrest in G1 via Blockade of Cyclin D-Cdk4 Expression in Non-Small Cell Lung Cancer (NSCLC)

scientific article published on 12 March 2013

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25 February 2020

Preclinical Activity of Simvastatin Induces Cell Cycle Arrest in G1 via Blockade of Cyclin D-Cdk4 Expression in Non-Small Cell Lung Cancer (NSCLC) (English)

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25 February 2020

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25 February 2020

author name string

Yu-Wei Liang

1

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25 February 2020

Chi-Chang Chang

2

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25 February 2020

Chao-Ming Hung

3

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25 February 2020

Tzu-Yu Chen

4

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25 February 2020

Tzuu-Yuan Huang

5

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25 February 2020

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12 March 2013

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25 February 2020

International Journal of Molecular Sciences

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25 February 2020

14

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25 February 2020

3

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25 February 2020

5806-5816

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25 February 2020

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Creative Commons Attribution 4.0 International

12 March 2013

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April 2022 Public Data File from Crossref

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Potential Therapeutic Role of Z-Isochaihulactone in Lung Cancer through Induction of Apoptosis via Notch Signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Solubility enhancement of simvastatin: a review.

1 reference

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29 September 2017

Economic evaluation of bevacizumab in the treatment of non-small cell lung cancer (NSCLC).

1 reference

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29 September 2017

Systematic review: potential preventive effects of statins against oesophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Statin use is associated with a reduced incidence of colorectal cancer: a colonoscopy-controlled case-control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Combination chemoprevention: future direction of colorectal cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Apoptosis Induction in Primary Human Colorectal Cancer Cell Lines and Retarded Tumor Growth in SCID Mice by Sulforaphane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Statins and prostate cancer: molecular and clinical aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Simvastatin improves wound strength after intestinal anastomosis in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

29 September 2017

Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

27 June 2018

HMG-CoA reductase inhibition causes increased necrosis and apoptosis in an in vivo mouse glioblastoma multiforme model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634414

27 June 2018

Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB

1 reference

https://pubmed.ncbi.nlm.nih.gov/23481641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiaging effects of simvastatin on vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23481641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/IJMS14035806

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23481641%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PMC publication ID

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Europe PubMed Central

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25 February 2020

PubMed publication ID

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Europe PubMed Central

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25 February 2020

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