(Q36790546)

16 August 2017

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title

Mitochondrial Ca2+ as a key regulator of cell life and death (English)

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16 August 2017

M Giacomello

1

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16 August 2017

I Drago

series ordinal

2

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16 August 2017

P Pizzo

series ordinal

3

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16 August 2017

T Pozzan

series ordinal

4

1 reference

16 August 2017

13 April 2007

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Cell Death & Differentiation

16 August 2017

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16 August 2017

14

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16 August 2017

1267-1274

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16 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402147

16 August 2017

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cites work

Disequilibrium between steady-state Ca2+ ion accumulation ratio and membrane potential in mitochondria. Pathway and role of Ca2+ ion efflux

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

A novel regulatory mechanism of the mitochondrial Ca2+ uniporter revealed by the p38 mitogen-activated protein kinase inhibitor SB202190.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

"Allosteric regulation" of calcium-uptake in rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Biphasic regulation of mitochondrial Ca2+ uptake by cytosolic Ca2+ concentration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondria as all-round players of the calcium game

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The sodium-calcium antiport of heart mitochondria is not electroneutral

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The mitochondrial calcium uniporter is a highly selective ion channel.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Intracellular calcium homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The comeback of mitochondria to calcium signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial Ca2+ homeostasis in intact cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Organelle-specific initiation of cell death pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The mitochondrion in apoptosis: how Pandora's box opens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Inhibition of the mitochondrial calcium uniporter by antibodies against a 40-kDa glycoproteinT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Specific inhibition of mitochondrial Ca2+ transport by antibodies directed to the Ca2+-binding glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Activation energies and enthalpies during Ca2+ transport in rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial Ca(2+) uptake depends on the spatial and temporal profile of cytosolic Ca(2+) signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The machinery of local Ca2+ signalling between sarco-endoplasmic reticulum and mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Ca2+ homeostasis in the agonist-sensitive internal store: functional interactions between mitochondria and the ER measured In situ in intact cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Modulation of Ca(2+) release and Ca(2+) oscillations in HeLa cells and fibroblasts by mitochondrial Ca(2+) uniporter stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Evidence that mitochondria buffer physiological Ca2+ loads in lizard motor nerve terminals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Quantitative analysis of mitochondrial Ca2+ uptake and release pathways in sympathetic neurons. Reconstruction of the recovery after depolarization-evoked [Ca2+]i elevations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Possible role for mitochondrial calcium in angiotensin II- and potassium-stimulated steroidogenesis in bovine adrenal glomerulosa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The role of calcium in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Calcium and apoptosis: facts and hypotheses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Apoptosis driven by IP(3)-linked mitochondrial calcium signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Modulation of endoplasmic reticulum calcium pump by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Cell signalling: IP3 receptors channel calcium into cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

A century of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Molecular biology and genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402147

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402147

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Dimensions Publication ID

16 August 2017

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1 reference