(Q36791058)

16 August 2017

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title

Use of pharmacodynamic principles to optimise dosage regimens for antibacterial agents in the elderly (English)

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16 August 2017

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Ayman M Noreddin

1

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16 August 2017

Virginia Haynes

series ordinal

2

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16 August 2017

publication date

1 January 2007

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16 August 2017

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16 August 2017

volume

24

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16 August 2017

issue

4

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16 August 2017

page(s)

275-292

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Geriatric pharmacology: safer prescribing for the elderly patient

16 August 2017

cites work

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https://api.crossref.org/works/10.2165%2F00002512-200724040-00002

Therapy insight: how changes in renal function with increasing age affect cardiovascular drug prescribing

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00002512-200724040-00002

Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00002512-200724040-00002

Brief communication: severe hepatotoxicity of telithromycin: three case reports and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00002512-200724040-00002

Intrapulmonary penetration of linezolid

21 January 2018

1 reference

12 December 2020

Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection

1 reference

12 December 2020

Clarithromycin pharmacokinetics in healthy young and elderly volunteers

1 reference

12 December 2020

Linezolid penetration into osteo-articular tissues

1 reference

12 December 2020

Optimising dosing strategies of antibacterials utilising pharmacodynamic principles: impact on the development of resistance

1 reference

12 December 2020

A randomized trial comparing the cardiac rhythm safety of moxifloxacin vs levofloxacin in elderly patients hospitalized with community-acquired pneumonia

1 reference

12 December 2020

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

1 reference

12 December 2020

Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

1 reference

12 December 2020

Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity

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12 December 2020

Outpatient gatifloxacin therapy and dysglycemia in older adults

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12 December 2020

Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model

1 reference

12 December 2020

Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis

1 reference

12 December 2020

Impact of selective antimicrobial agents on staphylococcal adherence to biomedical devices.

1 reference

12 December 2020

Penetration of ertapenem into different pulmonary compartments of patients undergoing lung surgery

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12 December 2020

Symposium on geriatrics--Part I: Drug prescribing for elderly patients

1 reference

12 December 2020

Pharmacodynamic activity of telithromycin against macrolide-susceptible and macrolide-resistant Streptococcus pneumoniae simulating clinically achievable free serum and epithelial lining fluid concentrations

1 reference

12 December 2020

Infectious disease outbreaks in nursing homes: an unappreciated hazard for frail elderly persons

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12 December 2020

The inoculum effect: fact or artifact?

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12 December 2020

Risk factors for toxicity in elderly patients given aminoglycosides once daily.

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12 December 2020

Cytochrome P-450 3A: interactions with dermatologic therapies

1 reference

12 December 2020

Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of fluoroquinolones in the respiratory tract

1 reference

12 December 2020

Linezolid-induced neuropathy

1 reference

12 December 2020

Telithromycin: the first ketolide antimicrobial

1 reference

12 December 2020

Pharmacokinetics of total and unbound ertapenem in healthy elderly subjects

1 reference

12 December 2020

Evolution of a new drug formulation: the rationale for high-dose, short-course therapy with azithromycin

1 reference

12 December 2020

Pandrug-resistant Pseudomonas aeruginosa among hospitalised patients: clinical features, risk-factors and outcomes.

1 reference

12 December 2020

Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoni

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12 December 2020

Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

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12 December 2020

Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy

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12 December 2020

Urinary tract infections. How to manage nursing home patients with or without chronic catheterization

1 reference

12 December 2020

Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection

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12 December 2020

Linezolid-induced inhibition of mitochondrial protein synthesis.

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12 December 2020

Fluoroquinolone-resistant Escherichia coli in the long-term care setting.

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12 December 2020

Longitudinal studies on the rate of decline in renal function with age.

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12 December 2020

Device-associated nosocomial infections in 55 intensive care units of 8 developing countries.

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12 December 2020

Antimicrobial management of complicated skin and skin structure infections in the era of emerging resistance

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12 December 2020

Pharmacokinetics of linezolid in subjects with renal dysfunction

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12 December 2020

New developments in antibacterial choice for lower respiratory tract infections in elderly patients

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12 December 2020

Safety and tolerability of linezolid

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12 December 2020

Impaired target site penetration of vancomycin in diabetic patients following cardiac surgery.

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12 December 2020

Guide to selection of fluoroquinolones in patients with lower respiratory tract infections

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12 December 2020

Delayed administration of antibiotics and atypical presentation in community-acquired pneumonia.

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12 December 2020

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12 December 2020

Profile of moxifloxacin drug interactions

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12 December 2020

Drug interactions and anti-infective therapies

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12 December 2020

Antimicrobial safety: focus on fluoroquinolones

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12 December 2020

Relationship between increased levofloxacin use and decreased susceptibility of Streptococcus pneumoniae in the United States

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12 December 2020

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

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12 December 2020

Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae

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12 December 2020

Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction

1 reference

12 December 2020

Prospective surveillance for healthcare-associated infections in German nursing home residents

1 reference

12 December 2020

Application of fluoroquinolone pharmacodynamics

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12 December 2020

Linezolid Compared with Eperezolid, Vancomycin, and Gentamicin in an In Vitro Model of Antimicrobial Lock Therapy for Staphylococcus epidermidis Central Venous Catheter-Related Biofilm Infections

1 reference

12 December 2020

Penetration of Moxifloxacin into Healthy and Inflamed Subcutaneous Adipose Tissues in Humans

1 reference

12 December 2020

Tissue pharmacokinetics of levofloxacin in human soft tissue infections

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12 December 2020

Preventability of invasive pneumococcal disease and assessment of current polysaccharide vaccine recommendations for adults: United States, 2001-2003

1 reference

12 December 2020

Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials

1 reference

12 December 2020

Penetration of piperacillin and tazobactam into inflamed soft tissue of patients with diabetic foot infection

1 reference

12 December 2020

Steady-state plasma and intrapulmonary concentrations of piperacillin/tazobactam 4 g/0.5 g administered to critically ill patients with severe nosocomial pneumonia

1 reference

12 December 2020

Intrapulmonary concentrations of telithromycin: clinical implications for respiratory tract infections due to Streptococcus pneumoniae

1 reference

12 December 2020

Steady-state serum and intrapulmonary pharmacokinetics and pharmacodynamics of tigecycline

1 reference

12 December 2020

Pharmacodynamic modeling of clarithromycin against macrolide-resistant [PCR-positive mef(A) or erm(B)] Streptococcus pneumoniae simulating clinically achievable serum and epithelial lining fluid free-drug concentrations

1 reference

12 December 2020

Penetration of meropenem into pneumonic human lung tissue as measured by in vivo microdialysis

1 reference

12 December 2020

Fluoroquinolones in the elderly: safety considerations

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12 December 2020

Liver function and phase I drug metabolism in the elderly: a paradox

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12 December 2020

Fluoroquinolone-associated tendinopathy: a critical review of the literature

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12 December 2020

Penetration of gentamicin into the alveolar lining fluid of critically ill patients with ventilator-associated pneumonia.

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12 December 2020

Quinolone efflux pumps play a central role in emergence of fluoroquinolone resistance in Streptococcus pneumoniae

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12 December 2020

Bacteriological and antimicrobial susceptibility profile of soft tissue infections from Northern India

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12 December 2020

Three-day vs longer duration of antibiotic treatment for cystitis in women: systematic review and meta-analysis

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12 December 2020

Decreasing invasive pneumococcal disease in the elderly: a state-level analysis

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12 December 2020

Antibiotic dosing in critically ill adult patients receiving continuous renal replacement therapy

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12 December 2020

Population pharmacokinetics of gentamicin in hospitalized patients receiving once-daily dosing

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12 December 2020

Fatal interaction between clarithromycin and colchicine in patients with renal insufficiency: a retrospective study

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12 December 2020

Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration

1 reference

12 December 2020

Carbapenems and monobactams: imipenem, meropenem, and aztreonam

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12 December 2020

Effects of three fluoroquinolones on QT analysis after standard treatment courses.

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12 December 2020

Pharmacokinetic/pharmacodynamic profile for tigecycline-a new glycylcycline antimicrobial agent

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12 December 2020

Drug dosage in the elderly: dermatological drugs

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12 December 2020

Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study

1 reference

12 December 2020

Tissue penetration by ertapenem, a parenteral carbapenem administered once daily, in suction-induced skin blister fluid in healthy young volunteers

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12 December 2020

Tissue distribution of imipenem in critically ill patients

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12 December 2020

Tobramycin penetration into epithelial lining fluid of patients with pneumonia

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12 December 2020

Antibiotic agents in the elderly

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12 December 2020

Penicillin dosing for pneumococcal pneumonia

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12 December 2020

Drug treatment of pneumococcal pneumonia in the elderly

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12 December 2020

Penetration of piperacillin and tazobactam into pneumonic human lung tissue measured by in vivo microdialysis

1 reference

12 December 2020

Ertapenem: review of a new carbapenem

1 reference

12 December 2020

Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000 mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP).

1 reference

12 December 2020

Comparison of the abilities of grepafloxacin and clarithromycin to eradicate potential bacterial pathogens from the sputa of patients with chronic bronchitis: influence of pharmacokinetic and pharmacodynamic variables.

1 reference

12 December 2020

Continuous versus intermittent intravenous administration of antibacterials with time-dependent action: a systematic review of pharmacokinetic and pharmacodynamic parameters

1 reference

12 December 2020

Linezolid reduces length of stay and duration of intravenous treatment compared with vancomycin for complicated skin and soft tissue infections due to suspected or proven methicillin-resistant Staphylococcus aureus (MRSA).

1 reference

12 December 2020

Activity of moxifloxacin, administered once a day, against Streptococcus pneumoniae in an in vitro pharmacodynamic model of infection

1 reference

12 December 2020

Comparative pharmacokinetics of azithromycin in serum and white blood cells of healthy subjects receiving a single-dose extended-release regimen versus a 3-day immediate-release regimen

1 reference

12 December 2020

Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of levofloxacin in intensive care patients.

1 reference

12 December 2020

Principles of appropriate antibiotic use.

1 reference

12 December 2020

Pharmacokinetics of ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose

1 reference

12 December 2020

Effect of moderate or severe hepatic impairment on clarithromycin pharmacokinetics

1 reference

12 December 2020

Individualized drug and dose: the clinical pharmacologist's calling or curse?

1 reference

12 December 2020

Optimizing aminoglycoside therapy for nosocomial pneumonia caused by gram-negative bacteria

1 reference

12 December 2020

Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa

1 reference

12 December 2020

Risk of serotonin syndrome with concomitant administration of linezolid and serotonin agonists

1 reference

12 December 2020

Tigecycline (Tygacil): the first in the glycylcycline class of antibiotics

1 reference

12 December 2020

Aminoglycoside dosage regimens after therapeutic drug monitoring

1 reference

12 December 2020

Comparison of bronchopulmonary pharmacokinetics of clarithromycin and azithromycin

1 reference

12 December 2020

In vivo measurement of levofloxacin penetration into lung tissue after cardiac surgery.

1 reference

12 December 2020

10.2165/00002512-200724040-00002

Identifiers

DOI

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Dimensions Publication ID

16 August 2017

1012044285

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