(Q36804429)

English

MDM2 forms homo- or heterodimers

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6804741)

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8 July 2022

1 reference

8 July 2022

Regulation of TP53 Degradation

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-6804741

1 reference

8 July 2022

p-S166,S188-MDM2 [nucleoplasm]

quantity

2

object of statement has role

1 reference

8 July 2022

p-S166,S188-MDM2,MDM4 [nucleoplasm]

quantity

1

object of statement has role

1 reference

8 July 2022

p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]

quantity

1

object of statement has role

1 reference

8 July 2022

p-S1981,Ac-K3016-ATM [nucleoplasm]

quantity

1

object of statement has role

1 reference

8 July 2022

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

1 reference

8 July 2022

Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage

1 reference

8 July 2022

The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo

1 reference

8 July 2022

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q36804429)

MDM2 forms homo- or heterodimers

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