(Q36806673)

English

Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway.

scientific article published on 29 January 2013

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scholarly article

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24 February 2020

Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway (English)

1 reference

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24 February 2020

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inferred from title

6

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24 February 2020

author name string

Cuiting Lv

1

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24 February 2020

Wenxia Sun

2

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24 February 2020

Haofen Sun

3

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24 February 2020

Shanjian Wei

4

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24 February 2020

Ruohua Chen

5

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24 February 2020

Caiguo Huang

7

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24 February 2020

publication date

29 January 2013

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24 February 2020

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24 February 2020

11

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24 February 2020

2

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24 February 2020

316-331

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24 February 2020

copyright license

Creative Commons Attribution 4.0 International

29 January 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

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The selenium analog of the chemopreventive compound S,S'-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer

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p53 in health and disease

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Benzo[a]pyrene, but not 2,3,7,8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cells: a distinct signaling pathway

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Cyclin B1 and CDK1: nuclear localization and upstream regulators

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A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

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Evidence for dysregulation of cell cycle by human polyomavirus, JCV, late auxiliary protein

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29 September 2017

MAPK signal pathways in the regulation of cell proliferation in mammalian cells

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29 September 2017

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

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Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

1 reference

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29 September 2017

Regulation of the G2/M transition by p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640382

29 September 2017

p53: death star

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640382

29 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640382

29 September 2017

Clinical perspectives on platinum resistance

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The role of p53 in the response to mitotic spindle damage

1 reference

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The cellular response to p53: the decision between life and death

1 reference

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Mechanisms of p53-mediated apoptosis

1 reference

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C-myc overexpression and p53 loss cooperate to promote genomic instability

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

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Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

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1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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1 reference

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27 June 2018

Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48.

1 reference

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1 reference

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Increasing complexity of Ras signaling.

1 reference

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p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Lung Cancer in Elderly Patients: An Analysis of the Surveillance, Epidemiology, and End Results Database

1 reference

https://pubmed.ncbi.nlm.nih.gov/23434831

12 December 2020

based on heuristic

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The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23434831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MD11020316

1 reference

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24 February 2020

1 reference

Europe PubMed Central

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24 February 2020

1 reference

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24 February 2020

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