(Q36808313)

English

The aging human orbitofrontal cortex: decreasing polyunsaturated fatty acid composition and associated increases in lipogenic gene expression and stearoyl-CoA desaturase activity

scientific article published on April 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The aging human orbitofrontal cortex: decreasing polyunsaturated fatty acid composition and associated increases in lipogenic gene expression and stearoyl-CoA desaturase activity (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

0 references

orbitofrontal cortex

0 references

author name string

Robert K McNamara

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Yanhong Liu

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ronald Jandacek

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Therese Rider

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Patrick Tso

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

publication date

1 April 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Prostaglandins, Leukotrienes and Essential Fatty Acids

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

78

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

4-5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

293-304

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Vulnerability of the orbitofrontal cortex to age-associated structural and functional brain changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Anatomical measurements of the orbitofrontal cortex in child and adolescent patients with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Role of omega-3 fatty acids in brain development and function: potential implications for the pathogenesis and prevention of psychopathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

C57BL/6J mice exhibit reduced dopamine D3 receptor-mediated locomotor-inhibitory function relative to DBA/2J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Subsyndromal depression in the elderly: underdiagnosed and undertreated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Anatomic evaluation of the orbitofrontal cortex in major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Regulation of stearoyl-CoA desaturases and role in metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Epidemiology of comorbid coronary artery disease and depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Reduced volume of orbitofrontal cortex in major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Cloning, expression, and fatty acid regulation of the human delta-5 desaturase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Regulation of the biosynthesis of 22:5n-6 and 22:6n-3: a complex intracellular process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Regulation of oleoyl-CoA synthesis in the peripheral nervous system: demonstration of a link with myelin synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Pex19p, a farnesylated protein essential for peroxisome biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Age-related changes in delta 6 and delta 5 desaturase activities in rat liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

29 September 2017

Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Neocortical neuron number in humans: effect of sex and age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Effect of dietary n-3 and n-6 fatty acids on fatty acid desaturation in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Abnormal profiles of polyunsaturated fatty acids in the brain, liver, kidney and retina of patients with peroxisomal disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Postnatal dietary fat influences mRNAS involved in myelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

27 June 2018

Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

The age-related degeneration of oligodendrocytes in the hippocampus of the senescence-accelerated mouse (SAM) P8: a quantitative immunohistochemical study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Age differences in orbitofrontal activation: an fMRI investigation of delayed match and nonmatch to sample.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Aging and prefrontal functions: dissociating orbitofrontal and dorsolateral abilities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Decrease in neuron size in docosahexaenoic acid-deficient brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

Alterations in eighteen-carbon saturated, monounsaturated and polyunsaturated fatty acid peroxisomal oxidation in mouse brain during development and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494852

5 September 2018

A Voxel-based Morphometric Study to Determine Individual Differences in Gray Matter Density Associated with Age and Cognitive Change Over Time

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of orbital frontal cortex volume in geriatric depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neocortical cell counts in normal human adult aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging influence on delta-6-desaturase activity and fatty acid composition of rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-associated changes in the content and fatty acid composition of brain glycerophospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for orbitofrontal pathology in bipolar disorder and major depression, but not in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary n-3 PUFA deprivation for 15 weeks upregulates elongase and desaturase expression in rat liver but not brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume

1 reference

https://pubmed.ncbi.nlm.nih.gov/18499418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.PLEFA.2008.04.001

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

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