(Q36809751)

16 August 2017

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title

Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease (English)

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16 August 2017

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Vincent KA

1

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16 August 2017

Jiang C

series ordinal

2

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16 August 2017

Boltje I

series ordinal

3

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16 August 2017

Kelly RA

series ordinal

4

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16 August 2017

publication date

1 May 2007

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16 August 2017

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16 August 2017

volume

14

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16 August 2017

issue

10

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16 August 2017

page(s)

781-789

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Update on drug-eluting coronary stents

16 August 2017

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VEGF coordinates interaction of pericytes and endothelial cells during vasculogenesis and experimental angiogenesis

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An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature

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21 January 2018

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Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices

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Angiogenesis as a therapeutic target

21 January 2018

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21 January 2018

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21 January 2018

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Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial

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Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle.

21 January 2018

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Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease

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Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 January 2018

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Oxygen sensing by HIF hydroxylases

21 January 2018

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Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis.

21 January 2018

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

21 January 2018

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Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue

21 January 2018

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Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia

21 January 2018

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A constitutively active hypoxia-inducible factor-1alpha/VP16 hybrid factor activates expression of the human B-type natriuretic peptide gene

21 January 2018

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Potential therapeutic gene for the treatment of ischemic disease: Ad2/hypoxia-inducible factor-1alpha (HIF-1)/VP16 enhances B-type natriuretic peptide gene expression via a HIF-1-responsive element

21 January 2018

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Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse

21 January 2018

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Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

21 January 2018

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

21 January 2018

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Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

21 January 2018

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21 January 2018

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Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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HIF-dependent induction of apical CD55 coordinates epithelial clearance of neutrophils

21 January 2018

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Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.

21 January 2018

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21 January 2018

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START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease

21 January 2018

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21 January 2018

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RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells

21 January 2018

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Hypoxia requires notch signaling to maintain the undifferentiated cell state

21 January 2018

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Hypoxia-regulated differentiation: let's step it up a Notch

21 January 2018

1 reference

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Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Cross-regulation of JAK and Src kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Early growth response-1 in cardiovascular pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Hepatocyte growth factor/scatter factor differentially regulates expression of proangiogenic factors through Egr-1 in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Arteriogenic growth factors, chemokines and proteases as a prerequisite for arteriogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Homozygous deletion of early growth response 1 gene and critical limb ischemia after vascular ligation in mice: evidence for a central role in vascular homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Parallels between tissue repair and embryo morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Comparative Evaluation of FGF-2–, VEGF-A–, and VEGF-C–Induced Angiogenesis, Lymphangiogenesis, Vascular Fenestrations, and Permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

Improving outcomes of cardiac surgery through cooperative efforts: the northern new England experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Matrix metalloproteinases and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Increased endogenous angiogenic response and hypoxia-inducible factor-1alpha in human critical limb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Growth factor-induced therapeutic neovascularization for ischaemic vascular disease: time for a re-evaluation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Angiogenesis in the human heart: gene and cell therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Chimeric VEGF-E(NZ7)/PlGF promotes angiogenesis via VEGFR-2 without significant enhancement of vascular permeability and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Oxygen sensing in the body

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Regulation of angiogenesis by hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Targeting hypoxia and angiogenesis through HIF-1alpha inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

The range of adaptation by collateral vessels after femoral artery occlusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Protection against myocardial ischemia-reperfusion injury by the angiogenic Masterswitch protein PR 39 gene therapy: the roles of HIF1alpha stabilization and FGFR1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

STAT3-mediated activation of myocardial capillary growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Molecular mechanisms controlling the coupled development of myocardium and coronary vasculature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Engineering zinc finger protein transcription factors: the therapeutic relevance of switching endogenous gene expression on or off at command

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302953

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302953

1 reference

16 August 2017

1 reference