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English
Recruitment and activation of Chk1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-176116)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
DNA replication
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
part of
G2/M DNA damage checkpoint
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
Activation of ATR in response to replication stress
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
exact match
https://identifiers.org/reactome:R-HSA-176116
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
has part(s)
ATP(4-)
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
Checkpoint kinase 1
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
ADP(3-)
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
p-S317,S345-CHEK1 [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
ATR:ATRIP [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
cites work
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
Identifiers
Reactome ID
R-HSA-176116
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-176116
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