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Tight junction modulation of the blood brain barrier: CNS delivery of small molecules
scientific article published on 8 January 2016
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scholarly article
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Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
review article
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stated in
Europe PubMed Central
title
Tight junction modulation of the blood brain barrier: CNS delivery of small molecules
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
main subject
blood–brain barrier
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based on heuristic
inferred from title
author
Chris Greene
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
author name string
Matthew Campbell
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
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3 April 2020
publication date
8 January 2016
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Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
published in
Tissue Barriers
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Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
volume
4
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
page(s)
e1138017
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Serine proteases and brain damage - is there a link?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
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29 September 2017
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Occludin: a novel integral membrane protein localizing at tight junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Transport of nutrients and hormones through the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Effect of anoxia on ion distribution in the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
High dose steroids in acute relapses of multiple sclerosis: MRI evidence for a possible mechanism of therapeutic effect
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Passage of cytokines across the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
29 September 2017
Sleep restriction impairs blood-brain barrier function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
RNAi-mediated reversible opening of the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
Blood-brain barrier disruption using mannitol: time course and electron microscopy studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
Differential permeability of cerebral capillary and choroid plexus to lanthanum ion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
27 June 2018
Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Therapies for neovascular age-related macular degeneration: current approaches and pharmacologic agents in development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
REM sleep loss and recovery regulates blood-brain barrier function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Structure and function of extracellular claudin domains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Graded reversible opening of the rat blood-brain barrier by intracarotid infusion of sodium caprate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Osmotic blood-brain barrier disruption chemotherapy for diffuse pontine gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Sleep disturbance and onset of type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Serum S-100beta as a possible marker of blood-brain barrier disruption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Effect of LPS on the permeability of the blood-brain barrier to insulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Intravenous cereport (RMP-7) modifies topographic uptake profile of carboplatin within rat glioma and brain surrounding tumor, elevates platinum levels, and enhances survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4836485
retrieved
5 September 2018
Exposure of tumor necrosis factor-α to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1080%2F21688370.2015.1138017
retrieved
21 January 2018
MicroRNA-155 negatively affects blood–brain barrier function during neuroinflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1080%2F21688370.2015.1138017
retrieved
21 January 2018
Mechanism of absorption enhancement in humans after rectal administration of ampicillin in suppositories containing sodium caprate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27141420
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A new principle for tight junction modulation based on occludin peptides
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27141420
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1080/21688370.2015.1138017
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
PMCID
4836485
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
PubMed ID
27141420
1 reference
stated in
Europe PubMed Central
PMCID
4836485
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27141420%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
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