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Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer
scientific article published on 24 January 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
main subject
Hepatitis C virus
1 reference
based on heuristic
inferred from title
virus
0 references
liver cancer
1 reference
based on heuristic
inferred from title
carcinogenesis
1 reference
based on heuristic
inferred from title
hepatitis C
1 reference
based on heuristic
inferred from title
author
David R. McGivern
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
author name string
S M Lemon
series ordinal
2
1 reference
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Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
language of work or name
English
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publication date
24 January 2011
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Europe PubMed Central
PMCID
3642622
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
volume
30
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
page(s)
1969-1983
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Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
issue
17
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Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/onc.2010.594
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DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor
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Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis
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NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner
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Hepatitis C virus core protein promotes proliferation of human hepatoma cells through enhancement of transforming growth factor expression via activation of nuclear factor- B
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29 September 2017
Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells
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29 September 2017
Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3.
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29 September 2017
E2 of hepatitis C virus inhibits apoptosis
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29 September 2017
Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase
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29 September 2017
DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control
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29 September 2017
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
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29 September 2017
Silencing of microRNAs in vivo with 'antagomirs'
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29 September 2017
Quantitative Analysis of the Hepatitis C Virus Replication Complex
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29 September 2017
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
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29 September 2017
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
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29 September 2017
Adaptive immune responses in acute and chronic hepatitis C virus infection
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29 September 2017
Unravelling hepatitis C virus replication from genome to function
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29 September 2017
Hepatitis C virus core variants isolated from liver tumor but not from adjacent non-tumor tissue interact with Smad3 and inhibit the TGF-beta pathway
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29 September 2017
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
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29 September 2017
Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription
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29 September 2017
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
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29 September 2017
Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
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29 September 2017
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor
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29 September 2017
Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication
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29 September 2017
Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees
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29 September 2017
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation
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29 September 2017
The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities
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29 September 2017
Hepatitis C viral proteins interact with Smad3 and differentially regulate TGF-beta/Smad3-mediated transcriptional activation
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PubMed Central
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29 September 2017
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.
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29 September 2017
Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication
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29 September 2017
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
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29 September 2017
Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein
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29 September 2017
The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade
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29 September 2017
Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase
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29 September 2017
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease
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29 September 2017
Current therapy for hepatitis C: pegylated interferon and ribavirin
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29 September 2017
The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis
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29 September 2017
The retinoblastoma tumour suppressor in development and cancer
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29 September 2017
A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades
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29 September 2017
Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3.
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29 September 2017
Hepatitis C virus NS5A protein binds TBP and p53, inhibiting their DNA binding and p53 interactions with TBP and ERCC3
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29 September 2017
Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block
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29 September 2017
HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis
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29 September 2017
Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells
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29 September 2017
Hepatocellular carcinoma associated with hepatitis C virus infection in Japan: projection to other countries in the foreseeable future
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29 September 2017
Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis
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29 September 2017
Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
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29 September 2017
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
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29 September 2017
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
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29 September 2017
Hepatitis C virus replication in mice with chimeric human livers
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29 September 2017
Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner
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29 September 2017
Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
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29 September 2017
Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death.
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29 September 2017
Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells
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29 September 2017
Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression
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29 September 2017
Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase
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29 September 2017
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
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29 September 2017
Hepatitis C virus core protein binds to a DEAD box RNA helicase
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29 September 2017
Hepatitis C virus core protein interacts with a human DEAD box protein DDX3
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29 September 2017
NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling
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29 September 2017
Hepatitis C virus core protein interacts with cellular putative RNA helicase
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29 September 2017
Complex formation of the nonstructural protein 3 of hepatitis C virus with the p53 tumor suppressor
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29 September 2017
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy
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29 September 2017
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
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29 September 2017
Immune pathogenesis of hepatocellular carcinoma.
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29 September 2017
Infection of a chimpanzee with hepatitis C virus grown in cell culture
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29 September 2017
Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase
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29 September 2017
Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis
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29 September 2017
Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity
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29 September 2017
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
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29 September 2017
Hepatocyte proliferative activity in chronic liver damage as assessed by the monoclonal antibody MIB1 Ki67 in archival material: the role of etiology, disease activity, iron, and lipid peroxidation
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29 September 2017
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase
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29 September 2017
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
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29 September 2017
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
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29 September 2017
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
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29 September 2017
Abnormal structure and expression of p53 gene in human hepatocellular carcinoma
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29 September 2017
The E2F transcription factor is a cellular target for the RB protein
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29 September 2017
Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells.
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27 June 2018
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27 June 2018
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27 June 2018
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
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27 June 2018
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An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma.
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5 September 2018
Hepatitis C virus NS5A protein interacts with beta-catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion
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5 September 2018
Visualizing hepatitis C virus infections in human liver by two-photon microscopy
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5 September 2018
Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening.
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5 September 2018
Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein
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5 September 2018
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5 September 2018
The coming wave of HCV-related liver disease: dilemmas and challenges
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5 September 2018
Hepatic expression of the proliferative marker Ki-67 and p53 protein in HBV or HCV cirrhosis in relation to dysplastic liver cell changes and hepatocellular carcinoma
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5 September 2018
Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
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5 September 2018
Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2.
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5 September 2018
Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis
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5 September 2018
Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.
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5 September 2018
Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells
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5 September 2018
Expression of hepatitis C virus non-structural 5A protein in the liver of transgenic mice
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5 September 2018
Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice
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5 September 2018
Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis
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5 September 2018
Disruption of the p16/cyclin D1/retinoblastoma protein pathway in the majority of human hepatocellular carcinomas.
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5 September 2018
Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis
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5 September 2018
Hepatitis C virus structural proteins induce liver cell injury in transgenic mice
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5 September 2018
Hepatic stellate cell activation and liver fibrosis are associated with necroinflammatory injury and Th1-like response in chronic hepatitis C.
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5 September 2018
Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth
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5 September 2018
Hepatocellular proliferation and development of hepatocellular carcinoma: a case-control study in chronic hepatitis C.
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5 September 2018
Transgenic expression of hepatitis C virus structural proteins in the mouse
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5 September 2018
Expression of hepatitis C virus envelope proteins in transgenic mice
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5 September 2018
Hepatocellular carcinoma occurring in nonfibrotic liver: Epidemiologic and histopathologic analysis of 80 French cases
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Identifiers
DOI
10.1038/ONC.2010.594
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PMCID
3642622
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed ID
21258404
1 reference
stated in
Europe PubMed Central
PMCID
3642622
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
ResearchGate publication ID
49777599
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