(Q36821512)

16 August 2017

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title

Autoimmunity in systemic sclerosis: current concepts (English)

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16 August 2017

Francesco Boin

1

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PubMed ID

17502048

16 August 2017

Antony Rosen

series ordinal

2

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16 August 2017

1 May 2007

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Current Rheumatology Reports

16 August 2017

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16 August 2017

9

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16 August 2017

2

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16 August 2017

165-172

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https://scigraph.springernature.com/pub.10.1007/s11926-007-0012-3

16 August 2017

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cites work

Autoantibodies to fibrillin-1 activate normal human fibroblasts in culture through the TGF-beta pathway to recapitulate the "scleroderma phenotype".

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11926-007-0012-3

Novel fibrogenic pathways are activated in response to endothelial apoptosis: implications in the pathophysiology of systemic sclerosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11926-007-0012-3

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11926-007-0012-3

Mechanism of serum-mediated endothelial injury in scleroderma: identification of a granular enzyme in scleroderma skin and sera

21 January 2018

1 reference

12 December 2020

Mutations in the human gene for fibrillin-1 (FBN1) in the Marfan syndrome and related disorders

1 reference

12 December 2020

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

1 reference

12 December 2020

Skewing of the CD8+ T-cell repertoire in the lungs of patients with systemic sclerosis

1 reference

12 December 2020

Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

1 reference

12 December 2020

T cell proliferative response induced by DNA topoisomerase I in patients with systemic sclerosis and healthy donors

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12 December 2020

Scleroderma: from cell and molecular mechanisms to disease models

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12 December 2020

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12 December 2020

Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis

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12 December 2020

Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis

1 reference

12 December 2020

Peripheral T lymphocytes from patients with early systemic sclerosis co-cultured with autologous fibroblasts undergo an oligoclonal expansion similar to that occurring in the skin

1 reference

12 December 2020

The presence of dominant T-cell clones in peripheral blood of patients with collagen vascular disorders: a prospective study of 97 cases

1 reference

12 December 2020

Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

1 reference

12 December 2020

Autoimmunity in scleroderma: the origin, pathogenetic role, and clinical significance of autoantibodies

1 reference

12 December 2020

The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system

1 reference

12 December 2020

Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice

1 reference

12 December 2020

Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases

1 reference

12 December 2020

B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis

1 reference

12 December 2020

Expression of allograft inflammatory factor 1 in tissues from patients with systemic sclerosis and in vitro differential expression of its isoforms in response to transforming growth factor beta.

1 reference

12 December 2020

Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis

1 reference

12 December 2020

Correlation of serum anti‐DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis

1 reference

12 December 2020

Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma

1 reference

12 December 2020

Sequential dermal microvascular and perivascular changes in the development of scleroderma

1 reference

12 December 2020

Longitudinal Study of Anticentromere and Antitopoisomerase-I Isotypes

1 reference

12 December 2020

Occurrence of an activated, profibrotic pattern of gene expression in lung CD8+ T cells from scleroderma patients

1 reference

12 December 2020

Mapping of the immunodominant T cell epitopes of the protein topoisomerase I.

1 reference

12 December 2020

Structural features of interstitial lung disease in systemic sclerosis

1 reference

12 December 2020

DNA topoisomerase I binding to fibroblasts induces monocyte adhesion and activation in the presence of anti-topoisomerase I autoantibodies from systemic sclerosis patients

1 reference

12 December 2020

Alveolar macrophages from systemic sclerosis patients: evidence for IL-4-mediated phenotype changes

1 reference

12 December 2020

Fibrillin controls TGF-beta activation

1 reference

12 December 2020

In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorionallantoic membrane assay

1 reference

12 December 2020

HLA and autoimmunity in scleroderma (systemic sclerosis).

1 reference

12 December 2020

Altered blood B lymphocyte homeostasis in systemic sclerosis: expanded naive B cells and diminished but activated memory B cells

1 reference

12 December 2020

Immunohistologic demonstration of platelet-derived growth factor (PDGF) and sis-oncogene expression in scleroderma

1 reference

12 December 2020

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts

1 reference

12 December 2020

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.

1 reference

12 December 2020

T cell lines from systemic sclerosis patients and healthy controls recognize multiple epitopes on DNA topoisomerase I

1 reference

12 December 2020

Absence of autoantibodies against correctly folded recombinant fibrillin-1 protein in systemic sclerosis patients

1 reference

12 December 2020

Elevated serum BAFF levels in patients with systemic sclerosis: enhanced BAFF signaling in systemic sclerosis B lymphocytes

1 reference

12 December 2020

Type 2 helper T-cell predominance and high CD30 expression in systemic sclerosis.

1 reference

12 December 2020

Reversal of experimental pulmonary hypertension by PDGF inhibition

1 reference

12 December 2020

Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis

1 reference

12 December 2020

Inhibition of AIF-1 expression by constitutive siRNA expression reduces macrophage migration, proliferation, and signal transduction initiated by atherogenic stimuli

1 reference

12 December 2020

Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease

1 reference

12 December 2020

The role of allograft inflammatory factor 1 in systemic sclerosis

1 reference

12 December 2020

Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis

1 reference

12 December 2020

Neuromuscular junction autoimmune disease: muscle specific kinase antibodies and treatments for myasthenia gravis

1 reference

12 December 2020

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

1 reference

12 December 2020

Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients

1 reference

12 December 2020

Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection

1 reference

12 December 2020

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

1 reference

12 December 2020

Increased frequency of interleukin 4 producing CD4+ and CD8+ cells in peripheral blood from patients with systemic sclerosis.

1 reference

12 December 2020

MHC class II associations with autoantibody and T cell immune responses to the scleroderma autoantigen topoisomerase I

1 reference

12 December 2020

Transforming growth factor-betas and vascular disorders

1 reference

12 December 2020

Oligoclonal T cell expansion in the skin of patients with systemic sclerosis

1 reference

12 December 2020

Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis

1 reference

12 December 2020

10.1007/S11926-007-0012-3

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17502048