(Q36823204)

16 August 2017

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title

Methylnaltrexone mechanisms of action and effects on opioid bowel dysfunction and other opioid adverse effects (English)

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16 August 2017

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Chun-Su Yuan

1

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PubMed ID

17504835

16 August 2017

language of work or name

English

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publication date

15 May 2007

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Annals of Pharmacotherapy

16 August 2017

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16 August 2017

41

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16 August 2017

6

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16 August 2017

984-993

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Naloxone infusion after prophylactic epidural morphine: effects on incidence of postoperative side-effects and quality of analgesia.

16 August 2017

1 reference

Treatment of opioid-induced constipation with oral naloxone: A pilot study

21 January 2018

1 reference

Assessment of nalmefene glucuronide as a selective gut opioid antagonist.

21 January 2018

1 reference

The use of quaternary narcotic antagonists in opiate research

21 January 2018

1 reference

Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists

21 January 2018

1 reference

Role of central versus peripheral opioid receptors in analgesia induced by repeated administration of opioid antagonists

21 January 2018

1 reference

Gastric effects of mu-, delta- and kappa-opioid receptor agonists on brainstem unitary responses in the neonatal rat.

21 January 2018

1 reference

Gastric effects of methylnaltrexone on mu, kappa, and delta opioid agonists induced brainstem unitary responses

21 January 2018

1 reference

Opioid antagonists: a review of their role in palliative care, focusing on use in opioid-related constipation

21 January 2018

1 reference

The central and peripheral influences of opioids on gastrointestinal propulsion

21 January 2018

1 reference

Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion

21 January 2018

1 reference

The importance of opioid tolerance: a therapeutic paradox

21 January 2018

1 reference

Incomplete cross tolerance and multiple mu opioid peptide receptors

21 January 2018

1 reference

Development of tolerance to the inhibitory effect of loperamide on gastrointestinal transit in mice

21 January 2018

1 reference

Opioid-induced gastrointestinal dysfunction

21 January 2018

1 reference

Pharmacokinetics of the opioid antagonist N-methylnaltrexone and evaluation of its effects on gastrointestinal tract function in horses treated or not treated with morphine

21 January 2018

1 reference

Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine

21 January 2018

1 reference

Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans

21 January 2018

1 reference

Naloxone, a specific opioid antagonist, reverses chronic idiopathic constipation

21 January 2018

1 reference

Naloxone treatment for irritable bowel syndrome--a randomized controlled trial with an oral formulation

21 January 2018

1 reference

Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects

21 January 2018

1 reference

Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbable carbohydrate

21 January 2018

1 reference

Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

21 January 2018

1 reference

Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial.

21 January 2018

1 reference

Effects of intravenous methylnaltrexone on opioid-induced gut motility and transit time changes in subjects receiving chronic methadone therapy: a pilot study

21 January 2018

1 reference

Opioid-induced emesis among hospitalized nonsurgical patients: effect on pain and quality of life.

21 January 2018

1 reference

Emetic and antiemetic effects of opioids in the dog.

21 January 2018

1 reference

The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors

21 January 2018

1 reference

21 January 2018

1 reference

Enkephalin receptors in the emetic chemoreceptor trigger zone of the dog

21 January 2018

1 reference

New Pharmacologic Approaches to the Prevention of Space/Motion Sickness

21 January 2018

1 reference

Action of opiates on gastrointestinal function

21 January 2018

1 reference

Effect of selective mu 1, mu 2 and delta 2 opioid receptor agonists on gastric functions in the rat.

21 January 2018

1 reference

Opioid-induced delay in gastric emptying: a peripheral mechanism in humans

21 January 2018

1 reference

Effects of low-dose morphine on gastric emptying in healthy volunteers.

21 January 2018

1 reference

Methylnaltrexone prevents morphine-induced kaolin intake in the rat.

21 January 2018

1 reference

21 January 2018

1 reference

Managing quality on an orthopedic service: ileus in the lumbar spinal fusion patient

21 January 2018

1 reference

Mechanisms and treatment of postoperative ileus

21 January 2018

1 reference

A clinical pathway to accelerate recovery after colonic resection

21 January 2018

1 reference

Opioid-induced bowel dysfunction: pathophysiology and potential new therapies

21 January 2018

1 reference

Operative stress response is reduced after laparoscopic compared to open cholecystectomy: the relationship with postoperative pain and ileus.

21 January 2018

1 reference

Effect of adrenergic and nitrergic blockade on experimental ileus in rats

21 January 2018

1 reference

Selective postoperative inhibition of gastrointestinal opioid receptors

21 January 2018

1 reference

Effects of codeine, morphine and a novel opioid pentapeptide BW443C, on cough, nociception and ventilation in the unanaesthetized guinea-pig

21 January 2018

1 reference

Efficacy of methylnaltrexone versus naloxone for reversal of morphine-induced depression of hypoxic ventilatory response.

21 January 2018

1 reference

Opiates, mast cells and histamine release

21 January 2018

1 reference

In vitro evaluation of the potential role of sulfite radical in morphine-associated histamine release

21 January 2018

1 reference

Efficacy of orally administered methylnaltrexone in decreasing subjective effects after intravenous morphine.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1345/APH.1K009

1 reference

16 August 2017

1 reference

PubMed ID

17504835